Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 189

1.

Laulimalide and synthetic laulimalide analogues are synergistic with paclitaxel and 2-methoxyestradiol.

Clark EA, Hills PM, Davidson BS, Wender PA, Mooberry SL.

Mol Pharm. 2006 Jul-Aug;3(4):457-67.

PMID:
16889440
2.
3.

The microtubule stabilizing agent laulimalide does not bind in the taxoid site, kills cells resistant to paclitaxel and epothilones, and may not require its epoxide moiety for activity.

Pryor DE, O'Brate A, Bilcer G, Díaz JF, Wang Y, Wang Y, Kabaki M, Jung MK, Andreu JM, Ghosh AK, Giannakakou P, Hamel E.

Biochemistry. 2002 Jul 23;41(29):9109-15.

PMID:
12119025
4.

In vitro and in vivo anticancer activities of synthetic (-)-laulimalide, a marine natural product microtubule stabilizing agent.

Liu J, Towle MJ, Cheng H, Saxton P, Reardon C, Wu J, Murphy EA, Kuznetsov G, Johannes CW, Tremblay MR, Zhao H, Pesant M, Fang FG, Vermeulen MW, Gallagher BM Jr, Littlefield BA.

Anticancer Res. 2007 May-Jun;27(3B):1509-18.

5.

Antiproliferative effects of 2-methoxyestradiol alone and in combination with chemotherapeutic agents on human endometrial cancer cells.

Chen CH, Lee WJ, Chang TC, Chen RJ, Chien CH, Chow SN.

Eur J Gynaecol Oncol. 2009;30(3):275-80.

PMID:
19697620
6.

Laulimalide and isolaulimalide, new paclitaxel-like microtubule-stabilizing agents.

Mooberry SL, Tien G, Hernandez AH, Plubrukarn A, Davidson BS.

Cancer Res. 1999 Feb 1;59(3):653-60.

7.

Synergistic suppression of microtubule dynamics by discodermolide and paclitaxel in non-small cell lung carcinoma cells.

Honore S, Kamath K, Braguer D, Horwitz SB, Wilson L, Briand C, Jordan MA.

Cancer Res. 2004 Jul 15;64(14):4957-64.

8.

Microtubule-stabilizing agents based on designed laulimalide analogues.

Mooberry SL, Randall-Hlubek DA, Leal RM, Hegde SG, Hubbard RD, Zhang L, Wender PA.

Proc Natl Acad Sci U S A. 2004 Jun 8;101(23):8803-8. Epub 2004 May 25.

9.

Novel 2-methoxyestradiol analogues with antitumor activity.

Tinley TL, Leal RM, Randall-Hlubek DA, Cessac JW, Wilkens LR, Rao PN, Mooberry SL.

Cancer Res. 2003 Apr 1;63(7):1538-49.

10.

Significant antitumor activity in vivo following treatment with the microtubule agent ENMD-1198.

LaVallee TM, Burke PA, Swartz GM, Hamel E, Agoston GE, Shah J, Suwandi L, Hanson AD, Fogler WE, Sidor CF, Treston AM.

Mol Cancer Ther. 2008 Jun;7(6):1472-82. doi: 10.1158/1535-7163.MCT-08-0107.

11.

Preclinical pharmacologic evaluation of MST-997, an orally active taxane with superior in vitro and in vivo efficacy in paclitaxel- and docetaxel-resistant tumor models.

Sampath D, Greenberger LM, Beyer C, Hari M, Liu H, Baxter M, Yang S, Rios C, Discafani C.

Clin Cancer Res. 2006 Jun 1;12(11 Pt 1):3459-69.

12.

Synergistic effects of peloruside A and laulimalide with taxoid site drugs, but not with each other, on tubulin assembly.

Hamel E, Day BW, Miller JH, Jung MK, Northcote PT, Ghosh AK, Curran DP, Cushman M, Nicolaou KC, Paterson I, Sorensen EJ.

Mol Pharmacol. 2006 Nov;70(5):1555-64. Epub 2006 Aug 3.

13.

In vitro synergy of paclitaxel (Taxol) and vinorelbine (navelbine) against human melanoma cell lines.

Photiou A, Shah P, Leong LK, Moss J, Retsas S.

Eur J Cancer. 1997 Mar;33(3):463-70.

PMID:
9155533
14.

STX140 is efficacious in vitro and in vivo in taxane-resistant breast carcinoma cells.

Newman SP, Foster PA, Stengel C, Day JM, Ho YT, Judde JG, Lassalle M, Prevost G, Leese MP, Potter BV, Reed MJ, Purohit A.

Clin Cancer Res. 2008 Jan 15;14(2):597-606. doi: 10.1158/1078-0432.CCR-07-1717.

15.

A steroid derivative with paclitaxel-like effects on tubulin polymerization.

Verdier-Pinard P, Wang Z, Mohanakrishnan AK, Cushman M, Hamel E.

Mol Pharmacol. 2000 Mar;57(3):568-75.

16.

beta-Tubulin mutations are associated with resistance to 2-methoxyestradiol in MDA-MB-435 cancer cells.

Gökmen-Polar Y, Escuin D, Walls CD, Soule SE, Wang Y, Sanders KL, Lavallee TM, Wang M, Guenther BD, Giannakakou P, Sledge GW Jr.

Cancer Res. 2005 Oct 15;65(20):9406-14.

17.

Synthesis of B-ring homologated estradiol analogues that modulate tubulin polymerization and microtubule stability.

Wang Z, Yang D, Mohanakrishnan AK, Fanwick PE, Nampoothiri P, Hamel E, Cushman M.

J Med Chem. 2000 Jun 15;43(12):2419-29.

PMID:
10882369
18.

Synergistic interactions between peloruside A and other microtubule-stabilizing and destabilizing agents in cultured human ovarian carcinoma cells and murine T cells.

Wilmes A, O'Sullivan D, Chan A, Chandrahasen C, Paterson I, Northcote PT, La Flamme AC, Miller JH.

Cancer Chemother Pharmacol. 2011 Jul;68(1):117-26. doi: 10.1007/s00280-010-1461-3. Epub 2010 Sep 17.

PMID:
20848285
19.

Estrogen effects on tubulin expression and taxane mediated cytotoxicity in prostate cancer cells.

Montgomery RB, Bonham M, Nelson PS, Grim J, Makary E, Vessella R, Stahl WL.

Prostate. 2005 Oct 1;65(2):141-50.

PMID:
15924336
20.

Combination of albendazole and 2-methoxyestradiol significantly improves the survival of HCT-116 tumor-bearing nude mice.

Ehteda A, Galettis P, Pillai K, Morris DL.

BMC Cancer. 2013 Feb 23;13:86. doi: 10.1186/1471-2407-13-86.

Supplemental Content

Support Center