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Items: 1 to 20 of 99

1.

Structure of a signaling-competent reelin fragment revealed by X-ray crystallography and electron tomography.

Nogi T, Yasui N, Hattori M, Iwasaki K, Takagi J.

EMBO J. 2006 Aug 9;25(15):3675-83.

2.

Structure of a receptor-binding fragment of reelin and mutational analysis reveal a recognition mechanism similar to endocytic receptors.

Yasui N, Nogi T, Kitao T, Nakano Y, Hattori M, Takagi J.

Proc Natl Acad Sci U S A. 2007 Jun 12;104(24):9988-93.

3.

Structural basis for specific recognition of reelin by its receptors.

Yasui N, Nogi T, Takagi J.

Structure. 2010 Mar 10;18(3):320-31. doi: 10.1016/j.str.2010.01.010.

4.

Functional importance of covalent homodimer of reelin protein linked via its central region.

Yasui N, Kitago Y, Beppu A, Kohno T, Morishita S, Gomi H, Nagae M, Hattori M, Takagi J.

J Biol Chem. 2011 Oct 7;286(40):35247-56. doi: 10.1074/jbc.M111.242719.

5.

C-terminal region-dependent change of antibody-binding to the Eighth Reelin repeat reflects the signaling activity of Reelin.

Kohno T, Nakano Y, Kitoh N, Yagi H, Kato K, Baba A, Hattori M.

J Neurosci Res. 2009 Nov 1;87(14):3043-53. doi: 10.1002/jnr.22143.

PMID:
19530167
6.

A 3D model of Reelin subrepeat regions predicts Reelin binding to carbohydrates.

Panteri R, Paiardini A, Keller F.

Brain Res. 2006 Oct 20;1116(1):222-30.

PMID:
16979599
7.

Reelin induces Erk1/2 signaling in cortical neurons through a non-canonical pathway.

Lee GH, Chhangawala Z, von Daake S, Savas JN, Yates JR 3rd, Comoletti D, D'Arcangelo G.

J Biol Chem. 2014 Jul 18;289(29):20307-17. doi: 10.1074/jbc.M114.576249.

8.

The crystal structure of the heparin-binding reelin-N domain of f-spondin.

Tan K, Duquette M, Liu JH, Lawler J, Wang JH.

J Mol Biol. 2008 Sep 19;381(5):1213-23. doi: 10.1016/j.jmb.2008.06.045.

9.

Structure of the F-spondin reeler domain reveals a unique beta-sandwich fold with a deformable disulfide-bonded loop.

Nagae M, Nishikawa K, Yasui N, Yamasaki M, Nogi T, Takagi J.

Acta Crystallogr D Biol Crystallogr. 2008 Nov;64(Pt 11):1138-45. doi: 10.1107/S0907444908028308.

PMID:
19020352
10.

Three novel repetitive units of reelin.

Ichihara H, Jingami H, Toh H.

Brain Res Mol Brain Res. 2001 Dec 30;97(2):190-3.

PMID:
11750076
11.

Cleavage within Reelin repeat 3 regulates the duration and range of the signaling activity of Reelin protein.

Koie M, Okumura K, Hisanaga A, Kamei T, Sasaki K, Deng M, Baba A, Kohno T, Hattori M.

J Biol Chem. 2014 May 2;289(18):12922-30. doi: 10.1074/jbc.M113.536326.

12.

Heterozygous reelin mutations cause autosomal-dominant lateral temporal epilepsy.

Dazzo E, Fanciulli M, Serioli E, Minervini G, Pulitano P, Binelli S, Di Bonaventura C, Luisi C, Pasini E, Striano S, Striano P, Coppola G, Chiavegato A, Radovic S, Spadotto A, Uzzau S, La Neve A, Giallonardo AT, Mecarelli O, Tosatto SC, Ottman R, Michelucci R, Nobile C.

Am J Hum Genet. 2015 Jun 4;96(6):992-1000. doi: 10.1016/j.ajhg.2015.04.020.

13.

The extremely conserved C-terminal region of Reelin is not necessary for secretion but is required for efficient activation of downstream signaling.

Nakano Y, Kohno T, Hibi T, Kohno S, Baba A, Mikoshiba K, Nakajima K, Hattori M.

J Biol Chem. 2007 Jul 13;282(28):20544-52.

14.

[Molecular mechanism and physiological significance of proteolytic cleavage of Reelin].

Kohno T, Hattori M.

Seikagaku. 2010 Oct;82(10):963-71. Review. Japanese. No abstract available.

PMID:
21077330
15.

Ephrin Bs are essential components of the Reelin pathway to regulate neuronal migration.

Sentürk A, Pfennig S, Weiss A, Burk K, Acker-Palmer A.

Nature. 2011 Apr 21;472(7343):356-60. doi: 10.1038/nature09874. Erratum in: Nature. 2011 Oct 13;478(7368):274.

PMID:
21460838
16.

Phosphatidylinositol 3-kinase interacts with the adaptor protein Dab1 in response to Reelin signaling and is required for normal cortical lamination.

Bock HH, Jossin Y, Liu P, Förster E, May P, Goffinet AM, Herz J.

J Biol Chem. 2003 Oct 3;278(40):38772-9.

17.

A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS-4) cleaves Reelin in an isoform-dependent manner.

Hisanaga A, Morishita S, Suzuki K, Sasaki K, Koie M, Kohno T, Hattori M.

FEBS Lett. 2012 Sep 21;586(19):3349-53. doi: 10.1016/j.febslet.2012.07.017.

18.

Interaction between Reelin and Notch signaling regulates neuronal migration in the cerebral cortex.

Hashimoto-Torii K, Torii M, Sarkisian MR, Bartley CM, Shen J, Radtke F, Gridley T, Sestan N, Rakic P.

Neuron. 2008 Oct 23;60(2):273-84. doi: 10.1016/j.neuron.2008.09.026.

19.

Splicing variations in the ligand-binding domain of ApoER2 results in functional differences in the binding properties to Reelin.

Hibi T, Mizutani M, Baba A, Hattori M.

Neurosci Res. 2009 Apr;63(4):251-8. doi: 10.1016/j.neures.2008.12.009.

PMID:
19167437
20.

Beta-amyloid impairs reelin signaling.

Cuchillo-Ibáñez I, Balmaceda V, Botella-López A, Rabano A, Avila J, Sáez-Valero J.

PLoS One. 2013 Aug 12;8(8):e72297. doi: 10.1371/journal.pone.0072297.

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