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Items: 1 to 20 of 76

1.

Predictive testing for complex diseases using multiple genes: fact or fiction?

Janssens AC, Aulchenko YS, Elefante S, Borsboom GJ, Steyerberg EW, van Duijn CM.

Genet Med. 2006 Jul;8(7):395-400.

PMID:
16845271
2.

The impact of genotype frequencies on the clinical validity of genomic profiling for predicting common chronic diseases.

Janssens AC, Moonesinghe R, Yang Q, Steyerberg EW, van Duijn CM, Khoury MJ.

Genet Med. 2007 Aug;9(8):528-35.

PMID:
17700391
3.

Value of genetic profiling for the prediction of coronary heart disease.

van der Net JB, Janssens AC, Sijbrands EJ, Steyerberg EW.

Am Heart J. 2009 Jul;158(1):105-10. doi: 10.1016/j.ahj.2009.04.022.

PMID:
19540399
4.

Analytical and simulation methods for estimating the potential predictive ability of genetic profiling: a comparison of methods and results.

Kundu S, Karssen LC, Janssens AC.

Eur J Hum Genet. 2012 Dec;20(12):1270-4. doi: 10.1038/ejhg.2012.89. Epub 2012 May 30.

5.

Discriminative accuracy of genomic profiling comparing multiplicative and additive risk models.

Moonesinghe R, Khoury MJ, Liu T, Janssens AC.

Eur J Hum Genet. 2011 Feb;19(2):180-5. doi: 10.1038/ejhg.2010.165. Epub 2010 Nov 17.

6.

How many genes underlie the occurrence of common complex diseases in the population?

Yang Q, Khoury MJ, Friedman J, Little J, Flanders WD.

Int J Epidemiol. 2005 Oct;34(5):1129-37. Epub 2005 Jul 25.

PMID:
16043441
7.

An epidemiologic assessment of genomic profiling for measuring susceptibility to common diseases and targeting interventions.

Khoury MJ, Yang Q, Gwinn M, Little J, Dana Flanders W.

Genet Med. 2004 Jan-Feb;6(1):38-47.

PMID:
14726808
8.

Evaluation of the discriminative accuracy of genomic profiling in the prediction of common complex diseases.

Moonesinghe R, Liu T, Khoury MJ.

Eur J Hum Genet. 2010 Apr;18(4):485-9. doi: 10.1038/ejhg.2009.209. Epub 2009 Nov 25.

9.

Improving the prediction of complex diseases by testing for multiple disease-susceptibility genes.

Yang Q, Khoury MJ, Botto L, Friedman JM, Flanders WD.

Am J Hum Genet. 2003 Mar;72(3):636-49. Epub 2003 Feb 14. Erratum in: Am J Hum Genet. 2004 Feb;74(2):372.

10.

The relationship between the sibling recurrence-risk ratio and genotype relative risk.

Rybicki BA, Elston RC.

Am J Hum Genet. 2000 Feb;66(2):593-604. Erratum in: Am J Hum Genet 2000 Aug;67(2):541.

11.

Clinical implications of old and new genes for open-angle glaucoma.

Ramdas WD, van Koolwijk LM, Cree AJ, Janssens AC, Amin N, de Jong PT, Wolfs RC, Gibson J, Kirwan JF, Hofman A, Rivadeneira F, Oostra BA, Uitterlinden AG, Ennis S, Lotery AJ, Lemij HG, Klaver CC, Vingerling JR, Jansonius NM, van Duijn CM.

Ophthalmology. 2011 Dec;118(12):2389-97. doi: 10.1016/j.ophtha.2011.05.040. Epub 2011 Aug 27.

PMID:
21872936
12.

Polymorphic deletions of the GSTT1 and GSTM1 genes and susceptibility to bladder cancer.

Salinas-Sánchez AS, Sánchez-Sánchez F, Donate-Moreno MJ, Rubio-del-Campo A, Gimenez-Bachs JM, Lorenzo-Romero JG, Serrano-Oviedo L, Escribano J.

BJU Int. 2011 Jun;107(11):1825-32. doi: 10.1111/j.1464-410X.2010.09683.x. Epub 2010 Oct 13.

13.

AUC-RF: a new strategy for genomic profiling with random forest.

Calle ML, Urrea V, Boulesteix AL, Malats N.

Hum Hered. 2011;72(2):121-32. doi: 10.1159/000330778. Epub 2011 Oct 11.

PMID:
21996641
14.
15.

Prevalence and inheritance of hip osteoarthritis in Iceland.

Ingvarsson T.

Acta Orthop Scand Suppl. 2000 Dec;298:1-46. Review.

PMID:
11338422
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18.

Does the addition of information on genotype improve prediction of the risk of melanoma and nonmelanoma skin cancer beyond that obtained from skin phenotype?

Dwyer T, Stankovich JM, Blizzard L, FitzGerald LM, Dickinson JL, Reilly A, Williamson J, Ashbolt R, Berwick M, Sale MM.

Am J Epidemiol. 2004 May 1;159(9):826-33.

PMID:
15105175
19.

Health-related disparities: influence of environmental factors.

Olden K, White SL.

Med Clin North Am. 2005 Jul;89(4):721-38. Review.

PMID:
15925646
20.

A unifying framework for evaluating the predictive power of genetic variants based on the level of heritability explained.

So HC, Sham PC.

PLoS Genet. 2010 Dec 2;6(12):e1001230. doi: 10.1371/journal.pgen.1001230.

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