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Items: 1 to 20 of 114

1.

BLOC-1 interacts with BLOC-2 and the AP-3 complex to facilitate protein trafficking on endosomes.

Di Pietro SM, Falcón-Pérez JM, Tenza D, Setty SR, Marks MS, Raposo G, Dell'Angelica EC.

Mol Biol Cell. 2006 Sep;17(9):4027-38. Epub 2006 Jul 12.

2.

BLOC-1 is required for cargo-specific sorting from vacuolar early endosomes toward lysosome-related organelles.

Setty SR, Tenza D, Truschel ST, Chou E, Sviderskaya EV, Theos AC, Lamoreux ML, Di Pietro SM, Starcevic M, Bennett DC, Dell'Angelica EC, Raposo G, Marks MS.

Mol Biol Cell. 2007 Mar;18(3):768-80. Epub 2006 Dec 20. Erratum in: Mol Biol Cell. 2017 Feb 1;28(3):500.

3.

BLOC-2, AP-3, and AP-1 proteins function in concert with Rab38 and Rab32 proteins to mediate protein trafficking to lysosome-related organelles.

Bultema JJ, Ambrosio AL, Burek CL, Di Pietro SM.

J Biol Chem. 2012 Jun 1;287(23):19550-63. doi: 10.1074/jbc.M112.351908. Epub 2012 Apr 16.

4.

ESCRT-I function is required for Tyrp1 transport from early endosomes to the melanosome limiting membrane.

Truschel ST, Simoes S, Setty SR, Harper DC, Tenza D, Thomas PC, Herman KE, Sackett SD, Cowan DC, Theos AC, Raposo G, Marks MS.

Traffic. 2009 Sep;10(9):1318-36. doi: 10.1111/j.1600-0854.2009.00955.x. Epub 2009 Jun 9.

5.
6.

BLOC-1 complex deficiency alters the targeting of adaptor protein complex-3 cargoes.

Salazar G, Craige B, Styers ML, Newell-Litwa KA, Doucette MM, Wainer BH, Falcon-Perez JM, Dell'Angelica EC, Peden AA, Werner E, Faundez V.

Mol Biol Cell. 2006 Sep;17(9):4014-26. Epub 2006 Jun 7.

7.

BLOC-2 targets recycling endosomal tubules to melanosomes for cargo delivery.

Dennis MK, Mantegazza AR, Snir OL, Tenza D, Acosta-Ruiz A, Delevoye C, Zorger R, Sitaram A, de Jesus-Rojas W, Ravichandran K, Rux J, Sviderskaya EV, Bennett DC, Raposo G, Marks MS, Setty SR.

J Cell Biol. 2015 May 25;209(4):563-77. doi: 10.1083/jcb.201410026.

8.

Reduced pigmentation (rp), a mouse model of Hermansky-Pudlak syndrome, encodes a novel component of the BLOC-1 complex.

Gwynn B, Martina JA, Bonifacino JS, Sviderskaya EV, Lamoreux ML, Bennett DC, Moriyama K, Huizing M, Helip-Wooley A, Gahl WA, Webb LS, Lambert AJ, Peters LL.

Blood. 2004 Nov 15;104(10):3181-9. Epub 2004 Jul 20.

9.

Biogenesis of lysosome-related organelles complex 3 (BLOC-3): a complex containing the Hermansky-Pudlak syndrome (HPS) proteins HPS1 and HPS4.

Nazarian R, Falcón-Pérez JM, Dell'Angelica EC.

Proc Natl Acad Sci U S A. 2003 Jul 22;100(15):8770-5. Epub 2003 Jul 7.

10.

AP-3 mediates tyrosinase but not TRP-1 trafficking in human melanocytes.

Huizing M, Sarangarajan R, Strovel E, Zhao Y, Gahl WA, Boissy RE.

Mol Biol Cell. 2001 Jul;12(7):2075-85.

11.

Differential recognition of a dileucine-based sorting signal by AP-1 and AP-3 reveals a requirement for both BLOC-1 and AP-3 in delivery of OCA2 to melanosomes.

Sitaram A, Dennis MK, Chaudhuri R, De Jesus-Rojas W, Tenza D, Setty SR, Wood CS, Sviderskaya EV, Bennett DC, Raposo G, Bonifacino JS, Marks MS.

Mol Biol Cell. 2012 Aug;23(16):3178-92. Epub 2012 Jun 20.

12.

Hermansky-Pudlak syndrome protein complexes associate with phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells.

Salazar G, Zlatic S, Craige B, Peden AA, Pohl J, Faundez V.

J Biol Chem. 2009 Jan 16;284(3):1790-802. doi: 10.1074/jbc.M805991200. Epub 2008 Nov 14.

13.

Melanocytes derived from patients with Hermansky-Pudlak Syndrome types 1, 2, and 3 have distinct defects in cargo trafficking.

Richmond B, Huizing M, Knapp J, Koshoffer A, Zhao Y, Gahl WA, Boissy RE.

J Invest Dermatol. 2005 Feb;124(2):420-7.

14.

Rab9A is required for delivery of cargo from recycling endosomes to melanosomes.

Mahanty S, Ravichandran K, Chitirala P, Prabha J, Jani RA, Setty SR.

Pigment Cell Melanoma Res. 2016 Jan;29(1):43-59. doi: 10.1111/pcmr.12434.

15.

Roles of BLOC-1 and adaptor protein-3 complexes in cargo sorting to synaptic vesicles.

Newell-Litwa K, Salazar G, Smith Y, Faundez V.

Mol Biol Cell. 2009 Mar;20(5):1441-53. doi: 10.1091/mbc.E08-05-0456. Epub 2009 Jan 14.

17.

Improper trafficking of melanocyte-specific proteins in Hermansky-Pudlak syndrome type-5.

Helip-Wooley A, Westbroek W, Dorward HM, Koshoffer A, Huizing M, Boissy RE, Gahl WA.

J Invest Dermatol. 2007 Jun;127(6):1471-8. Epub 2007 Feb 15.

18.

Cappuccino, a mouse model of Hermansky-Pudlak syndrome, encodes a novel protein that is part of the pallidin-muted complex (BLOC-1).

Ciciotte SL, Gwynn B, Moriyama K, Huizing M, Gahl WA, Bonifacino JS, Peters LL.

Blood. 2003 Jun 1;101(11):4402-7. Epub 2003 Feb 6.

19.

Role of adaptor complex AP-3 in targeting wild-type and mutated CD63 to lysosomes.

Rous BA, Reaves BJ, Ihrke G, Briggs JA, Gray SR, Stephens DJ, Banting G, Luzio JP.

Mol Biol Cell. 2002 Mar;13(3):1071-82.

20.

BLOC-1 Brings Together the Actin and Microtubule Cytoskeletons to Generate Recycling Endosomes.

Delevoye C, Heiligenstein X, Ripoll L, Gilles-Marsens F, Dennis MK, Linares RA, Derman L, Gokhale A, Morel E, Faundez V, Marks MS, Raposo G.

Curr Biol. 2016 Jan 11;26(1):1-13. doi: 10.1016/j.cub.2015.11.020. Epub 2015 Dec 24.

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