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Items: 1 to 20 of 266

1.

Critical assessment of pharmaceutical processes--A rationale for changing the synthetic route.

Butters M, Catterick D, Craig A, Curzons A, Dale D, Gillmore A, Green SP, Marziano I, Sherlock JP, White W.

Chem Rev. 2006 Jul;106(7):3002-27. Review. No abstract available.

PMID:
16836307
2.

Europe's sweeping chemical law puts medicines in peril.

Keim B.

Nat Med. 2007 Jan;13(1):4. No abstract available.

PMID:
17297677
3.

Generic substitution: the use of medicinal products containing different salts and implications for safety and efficacy.

Verbeeck RK, Kanfer I, Walker RB.

Eur J Pharm Sci. 2006 May;28(1-2):1-6. Epub 2006 Jan 18. Review.

PMID:
16413762
4.

Asymmetric synthesis of active pharmaceutical ingredients.

Farina V, Reeves JT, Senanayake CH, Song JJ.

Chem Rev. 2006 Jul;106(7):2734-93. Review. No abstract available.

PMID:
16836298
5.

Aseptic processing of protein pharmaceuticals.

Townsend M.

Pharm Biotechnol. 2002;14:129-89. Review. No abstract available.

PMID:
12189724
6.

Ozonolysis applications in drug synthesis.

Van Ornum SG, Champeau RM, Pariza R.

Chem Rev. 2006 Jul;106(7):2990-3001. Review. No abstract available.

PMID:
16836306
7.

March of the synthesis machines.

Sanderson K.

Nat Rev Drug Discov. 2015 May;14(5):299-300. doi: 10.1038/nrd4613. No abstract available.

PMID:
25924572
8.

Organolithium reagents in pharmaceutical asymmetric processes.

Wu G, Huang M.

Chem Rev. 2006 Jul;106(7):2596-616. Review. No abstract available.

PMID:
16836294
9.

Enabling continuous-flow chemistry in microstructured devices for pharmaceutical and fine-chemical production.

Kockmann N, Gottsponer M, Zimmermann B, Roberge DM.

Chemistry. 2008;14(25):7470-7. doi: 10.1002/chem.200800707.

PMID:
18613163
10.

FIP/AAPS joint workshop report: dissolution/in vitro release testing of novel/special dosage forms.

Brown CK, Friedel HD, Barker AR, Buhse LF, Keitel S, Cecil TL, Kraemer J, Morris JM, Reppas C, Stickelmeyer MP, Yomota C, Shah VP.

AAPS PharmSciTech. 2011 Jun;12(2):782-94. doi: 10.1208/s12249-011-9634-x. Epub 2011 Jun 18. No abstract available.

11.

New opportunities for biocatalysis: making pharmaceutical processes greener.

Woodley JM.

Trends Biotechnol. 2008 Jun;26(6):321-7. doi: 10.1016/j.tibtech.2008.03.004. Epub 2008 Apr 22. Review.

PMID:
18436317
12.

[Synthetic enantiomers of drugs].

Knabe J.

Pharm Unserer Zeit. 1995 Nov;24(6):324-30. Review. German. No abstract available.

PMID:
8592713
13.

Expanding the scope of crystal form evaluation in pharmaceutical science.

Peterson ML, Hickey MB, Zaworotko MJ, Almarsson O.

J Pharm Pharm Sci. 2006;9(3):317-26. Review.

14.

[An advancement in drug research: rational drug design with combinatorial chemistry].

Pindur U.

Pharm Unserer Zeit. 1997 Jan;26(1):24-30. Review. German. No abstract available. Erratum in: Pharm Unserer Zeit 1997 Mar;26(2):112.

PMID:
9157462
15.

On the development of new biocatalytic processes for practical pharmaceutical synthesis.

Huisman GW, Collier SJ.

Curr Opin Chem Biol. 2013 Apr;17(2):284-92. doi: 10.1016/j.cbpa.2013.01.017. Epub 2013 Feb 22. Review.

PMID:
23462589
16.

Supercritical carbon dioxide processing of active pharmaceutical ingredients for polymorphic control and for complex formation.

Moribe K, Tozuka Y, Yamamoto K.

Adv Drug Deliv Rev. 2008 Feb 14;60(3):328-38. Epub 2007 Oct 5. Review.

PMID:
18006109
17.

Synthesis of chiral building blocks for use in drug discovery.

Marino ST, Stachurska-Buczek D, Huggins DA, Krywult BM, Sheehan CS, Nguyen T, Choi N, Parsons JG, Griffiths PG, James IW, Bray AM, White JM, Boyce RS.

Molecules. 2004 May 31;9(6):405-26.

18.

Making medicinal chemistry more effective--application of Lean Sigma to improve processes, speed and quality.

Andersson S, Armstrong A, Björe A, Bowker S, Chapman S, Davies R, Donald C, Egner B, Elebring T, Holmqvist S, Inghardt T, Johannesson P, Johansson M, Johnstone C, Kemmitt P, Kihlberg J, Korsgren P, Lemurell M, Moore J, Pettersson JA, Pointon H, Pontén F, Schofield P, Selmi N, Whittamore P.

Drug Discov Today. 2009 Jun;14(11-12):598-604. doi: 10.1016/j.drudis.2009.03.005. Epub 2009 Mar 11. Review.

PMID:
19508922
19.

Biocatalysis for pharmaceutical intermediates: the future is now.

Pollard DJ, Woodley JM.

Trends Biotechnol. 2007 Feb;25(2):66-73. Epub 2006 Dec 20. Review.

PMID:
17184862
20.

Enzymes in the synthesis of chiral drugs.

Margolin AL.

Enzyme Microb Technol. 1993 Apr;15(4):266-80. Review.

PMID:
7763611

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