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IRP1-independent alterations of cardiac iron metabolism in doxorubicin-treated mice.

Corna G, Galy B, Hentze MW, Cairo G.

J Mol Med (Berl). 2006 Jul;84(7):551-60. Epub 2006 Jun 13.


Excess capacity of the iron regulatory protein system.

Wang W, Di X, D'Agostino RB Jr, Torti SV, Torti FM.

J Biol Chem. 2007 Aug 24;282(34):24650-9. Epub 2007 Jun 28.


Iron regulatory protein 1 outcompetes iron regulatory protein 2 in regulating cellular iron homeostasis in response to nitric oxide.

Styś A, Galy B, Starzyński RR, Smuda E, Drapier JC, Lipiński P, Bouton C.

J Biol Chem. 2011 Jul 1;286(26):22846-54. doi: 10.1074/jbc.M111.231902. Epub 2011 May 12.


Complete loss of iron regulatory proteins 1 and 2 prevents viability of murine zygotes beyond the blastocyst stage of embryonic development.

Smith SR, Ghosh MC, Ollivierre-Wilson H, Hang Tong W, Rouault TA.

Blood Cells Mol Dis. 2006 Mar-Apr;36(2):283-7. Epub 2006 Feb 15.


Mammalian iron metabolism and its control by iron regulatory proteins.

Anderson CP, Shen M, Eisenstein RS, Leibold EA.

Biochim Biophys Acta. 2012 Sep;1823(9):1468-83. doi: 10.1016/j.bbamcr.2012.05.010. Epub 2012 May 17. Review.


Iron regulatory protein-2 knockout increases perihematomal ferritin expression and cell viability after intracerebral hemorrhage.

Chen M, Awe OO, Chen-Roetling J, Regan RF.

Brain Res. 2010 Jun 14;1337:95-103. doi: 10.1016/j.brainres.2010.04.018. Epub 2010 Apr 24.


Genetic ablations of iron regulatory proteins 1 and 2 reveal why iron regulatory protein 2 dominates iron homeostasis.

Meyron-Holtz EG, Ghosh MC, Iwai K, LaVaute T, Brazzolotto X, Berger UV, Land W, Ollivierre-Wilson H, Grinberg A, Love P, Rouault TA.

EMBO J. 2004 Jan 28;23(2):386-95. Epub 2004 Jan 15.


Mammalian tissue oxygen levels modulate iron-regulatory protein activities in vivo.

Meyron-Holtz EG, Ghosh MC, Rouault TA.

Science. 2004 Dec 17;306(5704):2087-90.


Tempol-mediated activation of latent iron regulatory protein activity prevents symptoms of neurodegenerative disease in IRP2 knockout mice.

Ghosh MC, Tong WH, Zhang D, Ollivierre-Wilson H, Singh A, Krishna MC, Mitchell JB, Rouault TA.

Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):12028-33. doi: 10.1073/pnas.0805361105. Epub 2008 Aug 6.


Alteration of iron regulatory proteins (IRP1 and IRP2) and ferritin in the brains of scrapie-infected mice.

Kim BH, Jun YC, Jin JK, Kim JI, Kim NH, Leibold EA, Connor JR, Choi EK, Carp RI, Kim YS.

Neurosci Lett. 2007 Jul 18;422(3):158-63. Epub 2007 Jun 14.


Changed iron regulation in scrapie-infected neuroblastoma cells.

Fernaeus S, Hälldin J, Bedecs K, Land T.

Brain Res Mol Brain Res. 2005 Feb 18;133(2):266-73.


The role of iron regulatory proteins in mammalian iron homeostasis and disease.

Rouault TA.

Nat Chem Biol. 2006 Aug;2(8):406-14. Review.


Iron metabolism and the IRE/IRP regulatory system: an update.

Pantopoulos K.

Ann N Y Acad Sci. 2004 Mar;1012:1-13. Review.


The IRP/IRE system in vivo: insights from mouse models.

Wilkinson N, Pantopoulos K.

Front Pharmacol. 2014 Jul 28;5:176. doi: 10.3389/fphar.2014.00176. eCollection 2014. Review.


Doxorubicin paradoxically protects cardiomyocytes against iron-mediated toxicity: role of reactive oxygen species and ferritin.

Corna G, Santambrogio P, Minotti G, Cairo G.

J Biol Chem. 2004 Apr 2;279(14):13738-45. Epub 2004 Jan 22.


Iron regulatory protein 1 is not required for the modulation of ferritin and transferrin receptor expression by iron in a murine pro-B lymphocyte cell line.

Schalinske KL, Blemings KP, Steffen DW, Chen OS, Eisenstein RS.

Proc Natl Acad Sci U S A. 1997 Sep 30;94(20):10681-6.


A synergistic role of IRP1 and FBXL5 proteins in coordinating iron metabolism during cell proliferation.

Johnson NB, Deck KM, Nizzi CP, Eisenstein RS.

J Biol Chem. 2017 Sep 22;292(38):15976-15989. doi: 10.1074/jbc.M117.785741. Epub 2017 Aug 2.

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