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Items: 1 to 20 of 159

1.

Loss of cell polarity drives tumor growth and invasion through JNK activation in Drosophila.

Igaki T, Pagliarini RA, Xu T.

Curr Biol. 2006 Jun 6;16(11):1139-46.

2.

Scribble mutants promote aPKC and JNK-dependent epithelial neoplasia independently of Crumbs.

Leong GR, Goulding KR, Amin N, Richardson HE, Brumby AM.

BMC Biol. 2009 Sep 24;7:62. doi: 10.1186/1741-7007-7-62.

3.

A genetic screen in Drosophila for metastatic behavior.

Pagliarini RA, Xu T.

Science. 2003 Nov 14;302(5648):1227-31. Epub 2003 Oct 9.

4.

Activation of JNK signaling links lgl mutations to disruption of the cell polarity and epithelial organization in Drosophila imaginal discs.

Zhu M, Xin T, Weng S, Gao Y, Zhang Y, Li Q, Li M.

Cell Res. 2010 Feb;20(2):242-5. doi: 10.1038/cr.2010.2. Epub 2010 Jan 12. No abstract available.

PMID:
20066009
5.

Ras promotes cell survival by antagonizing both JNK and Hid signals in the Drosophila eye.

Wu Y, Zhuang Y, Han M, Xu T, Deng K.

BMC Dev Biol. 2009 Oct 20;9:53. doi: 10.1186/1471-213X-9-53.

6.

Rho1-Wnd signaling regulates loss-of-cell polarity-induced cell invasion in Drosophila.

Ma X, Chen Y, Zhang S, Xu W, Shao Y, Yang Y, Li W, Li M, Xue L.

Oncogene. 2016 Feb 18;35(7):846-55. doi: 10.1038/onc.2015.137. Epub 2015 May 11.

PMID:
25961917
7.

A dual function of Drosophila capping protein on DE-cadherin maintains epithelial integrity and prevents JNK-mediated apoptosis.

Jezowska B, Fernández BG, Amândio AR, Duarte P, Mendes C, Brás-Pereira C, Janody F.

Dev Biol. 2011 Dec 1;360(1):143-59. doi: 10.1016/j.ydbio.2011.09.016. Epub 2011 Sep 22.

8.

Tumor suppressor CYLD regulates JNK-induced cell death in Drosophila.

Xue L, Igaki T, Kuranaga E, Kanda H, Miura M, Xu T.

Dev Cell. 2007 Sep;13(3):446-54.

9.

Correcting developmental errors by apoptosis: lessons from Drosophila JNK signaling.

Igaki T.

Apoptosis. 2009 Aug;14(8):1021-8. doi: 10.1007/s10495-009-0361-7. Review.

PMID:
19466550
10.

Mutations in rugose promote cell type-specific apoptosis in the Drosophila eye.

Wech I, Nagel AC.

Cell Death Differ. 2005 Feb;12(2):145-52.

11.

Modeling transformation and metastasis in Drosophila.

Tapon N.

Cancer Cell. 2003 Nov;4(5):333-5. Review.

12.

Beta 4 integrin amplifies ErbB2 signaling to promote mammary tumorigenesis.

Guo W, Pylayeva Y, Pepe A, Yoshioka T, Muller WJ, Inghirami G, Giancotti FG.

Cell. 2006 Aug 11;126(3):489-502.

13.

Loss of human Scribble cooperates with H-Ras to promote cell invasion through deregulation of MAPK signalling.

Dow LE, Elsum IA, King CL, Kinross KM, Richardson HE, Humbert PO.

Oncogene. 2008 Oct 9;27(46):5988-6001. doi: 10.1038/onc.2008.219. Epub 2008 Jul 21.

PMID:
18641685
14.
15.

CYLD: a multifunctional deubiquitinase.

Glittenberg M, Ligoxygakis P.

Fly (Austin). 2007 Nov-Dec;1(6):330-2. Epub 2007 Nov 10. Review.

PMID:
18820455
16.

dXNP, a Drosophila homolog of XNP/ATRX, induces apoptosis via Jun-N-terminal kinase activation.

Lee NG, Hong YK, Yu SY, Han SY, Geum D, Cho KS.

FEBS Lett. 2007 Jun 12;581(14):2625-32. Epub 2007 May 11.

17.

JNK- and Fos-regulated Mmp1 expression cooperates with Ras to induce invasive tumors in Drosophila.

Uhlirova M, Bohmann D.

EMBO J. 2006 Nov 15;25(22):5294-304. Epub 2006 Nov 2.

18.

Role of JNK in tumor development.

Kennedy NJ, Davis RJ.

Cell Cycle. 2003 May-Jun;2(3):199-201. Review.

PMID:
12734425
19.

Site-specific phosphorylation of raf in cells containing oncogenic ras-p21 is likely mediated by jun-N-terminal kinase.

Adler V, Bowne W, Michl J, Sookraj KA, Ikram K, Pestka S, Izotova L, Zenilman M, Friedman FK, Qu Y, Pincus MR.

Ann Clin Lab Sci. 2008 Winter;38(1):47-56.

PMID:
18316782
20.

Interplay among Drosophila transcription factors Ets21c, Fos and Ftz-F1 drives JNK-mediated tumor malignancy.

Külshammer E, Mundorf J, Kilinc M, Frommolt P, Wagle P, Uhlirova M.

Dis Model Mech. 2015 Oct 1;8(10):1279-93. doi: 10.1242/dmm.020719. Epub 2015 Aug 6.

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