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Items: 1 to 20 of 130

1.

A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span.

Lehtinen MK, Yuan Z, Boag PR, Yang Y, Villén J, Becker EB, DiBacco S, de la Iglesia N, Gygi S, Blackwell TK, Bonni A.

Cell. 2006 Jun 2;125(5):987-1001.

2.

The c-Abl-MST1 signaling pathway mediates oxidative stress-induced neuronal cell death.

Xiao L, Chen D, Hu P, Wu J, Liu W, Zhao Y, Cao M, Fang Y, Bi W, Zheng Z, Ren J, Ji G, Wang Y, Yuan Z.

J Neurosci. 2011 Jun 29;31(26):9611-9. doi: 10.1523/JNEUROSCI.0035-11.2011.

3.

Effects of Caenorhabditis elegans sgk-1 mutations on lifespan, stress resistance, and DAF-16/FoxO regulation.

Chen AT, Guo C, Dumas KJ, Ashrafi K, Hu PJ.

Aging Cell. 2013 Oct;12(5):932-40. doi: 10.1111/acel.12120. Epub 2013 Jul 19.

4.

EAK proteins: novel conserved regulators of C. elegans lifespan.

Williams TW, Dumas KJ, Hu PJ.

Aging (Albany NY). 2010 Oct;2(10):742-7.

5.

Regulation of neuronal cell death by c-Abl-Hippo/MST2 signaling pathway.

Liu W, Wu J, Xiao L, Bai Y, Qu A, Zheng Z, Yuan Z.

PLoS One. 2012;7(5):e36562. doi: 10.1371/journal.pone.0036562. Epub 2012 May 9.

6.

Increased life span from overexpression of superoxide dismutase in Caenorhabditis elegans is not caused by decreased oxidative damage.

Cabreiro F, Ackerman D, Doonan R, Araiz C, Back P, Papp D, Braeckman BP, Gems D.

Free Radic Biol Med. 2011 Oct 15;51(8):1575-82. doi: 10.1016/j.freeradbiomed.2011.07.020. Epub 2011 Jul 31.

7.

Functional interaction between beta-catenin and FOXO in oxidative stress signaling.

Essers MA, de Vries-Smits LM, Barker N, Polderman PE, Burgering BM, Korswagen HC.

Science. 2005 May 20;308(5725):1181-4.

8.

The evolutionarily conserved longevity determinants HCF-1 and SIR-2.1/SIRT1 collaborate to regulate DAF-16/FOXO.

Rizki G, Iwata TN, Li J, Riedel CG, Picard CL, Jan M, Murphy CT, Lee SS.

PLoS Genet. 2011 Sep;7(9):e1002235. doi: 10.1371/journal.pgen.1002235. Epub 2011 Sep 1.

9.

EAK-7 controls development and life span by regulating nuclear DAF-16/FoxO activity.

Alam H, Williams TW, Dumas KJ, Guo C, Yoshina S, Mitani S, Hu PJ.

Cell Metab. 2010 Jul 7;12(1):30-41. doi: 10.1016/j.cmet.2010.05.004.

10.

Regulation of neuronal cell death by MST1-FOXO1 signaling.

Yuan Z, Lehtinen MK, Merlo P, Villén J, Gygi S, Bonni A.

J Biol Chem. 2009 Apr 24;284(17):11285-92. doi: 10.1074/jbc.M900461200. Epub 2009 Feb 16.

11.

An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C. elegans.

Greer EL, Dowlatshahi D, Banko MR, Villen J, Hoang K, Blanchard D, Gygi SP, Brunet A.

Curr Biol. 2007 Oct 9;17(19):1646-56. Epub 2007 Sep 27.

12.

E2F transcription factor 1 regulates cellular and organismal senescence by inhibiting Forkhead box O transcription factors.

Xie Q, Peng S, Tao L, Ruan H, Yang Y, Li TM, Adams U, Meng S, Bi X, Dong MQ, Yuan Z.

J Biol Chem. 2014 Dec 5;289(49):34205-13. doi: 10.1074/jbc.M114.587170. Epub 2014 Oct 24.

13.

Epigallocatechin gallate-induced modulation of FoxO signaling in mammalian cells and C. elegans: FoxO stimulation is masked via PI3K/Akt activation by hydrogen peroxide formed in cell culture.

Bartholome A, Kampkötter A, Tanner S, Sies H, Klotz LO.

Arch Biochem Biophys. 2010 Sep 1;501(1):58-64. doi: 10.1016/j.abb.2010.05.024. Epub 2010 May 27.

PMID:
20513639
14.
15.

C. elegans 14-3-3 proteins regulate life span and interact with SIR-2.1 and DAF-16/FOXO.

Wang Y, Oh SW, Deplancke B, Luo J, Walhout AJ, Tissenbaum HA.

Mech Ageing Dev. 2006 Sep;127(9):741-7. Epub 2006 Jul 24.

PMID:
16860373
16.

Tetrahydrocurcumin extends life span and inhibits the oxidative stress response by regulating the FOXO forkhead transcription factor.

Xiang L, Nakamura Y, Lim YM, Yamasaki Y, Kurokawa-Nose Y, Maruyama W, Osawa T, Matsuura A, Motoyama N, Tsuda L.

Aging (Albany NY). 2011 Nov;3(11):1098-109.

17.

JNK/FOXO-mediated neuronal expression of fly homologue of peroxiredoxin II reduces oxidative stress and extends life span.

Lee KS, Iijima-Ando K, Iijima K, Lee WJ, Lee JH, Yu K, Lee DS.

J Biol Chem. 2009 Oct 23;284(43):29454-61. doi: 10.1074/jbc.M109.028027. Epub 2009 Aug 31.

18.

Caenorhabditis elegans HCF-1 functions in longevity maintenance as a DAF-16 regulator.

Li J, Ebata A, Dong Y, Rizki G, Iwata T, Lee SS.

PLoS Biol. 2008 Sep 30;6(9):e233. doi: 10.1371/journal.pbio.0060233.

19.

JNK regulates lifespan in Caenorhabditis elegans by modulating nuclear translocation of forkhead transcription factor/DAF-16.

Oh SW, Mukhopadhyay A, Svrzikapa N, Jiang F, Davis RJ, Tissenbaum HA.

Proc Natl Acad Sci U S A. 2005 Mar 22;102(12):4494-9. Epub 2005 Mar 14.

20.

Expression of Drosophila FOXO regulates growth and can phenocopy starvation.

Kramer JM, Davidge JT, Lockyer JM, Staveley BE.

BMC Dev Biol. 2003 Jul 5;3:5. Epub 2003 Jul 5.

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