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Items: 1 to 20 of 122

1.

Caspase inhibitors reduce severity of cartilage lesions in experimental osteoarthritis.

D'Lima D, Hermida J, Hashimoto S, Colwell C, Lotz M.

Arthritis Rheum. 2006 Jun;54(6):1814-21.

2.

Selective inhibition of inducible nitric oxide synthase reduces progression of experimental osteoarthritis in vivo: possible link with the reduction in chondrocyte apoptosis and caspase 3 level.

Pelletier JP, Jovanovic DV, Lascau-Coman V, Fernandes JC, Manning PT, Connor JR, Currie MG, Martel-Pelletier J.

Arthritis Rheum. 2000 Jun;43(6):1290-9.

3.

Chondrocyte apoptosis and nitric oxide production during experimentally induced osteoarthritis.

Hashimoto S, Takahashi K, Amiel D, Coutts RD, Lotz M.

Arthritis Rheum. 1998 Jul;41(7):1266-74.

PMID:
9663485
4.

Licofelone (ML-3000), a dual inhibitor of 5-lipoxygenase and cyclooxygenase, reduces the level of cartilage chondrocyte death in vivo in experimental dog osteoarthritis: inhibition of pro-apoptotic factors.

Boileau C, Martel-Pelletier J, Jouzeau JY, Netter P, Moldovan F, Laufer S, Tries S, Pelletier JP.

J Rheumatol. 2002 Jul;29(7):1446-53.

PMID:
12136904
5.
6.

Carboxymethylated chitin reduces MMP-1 expression in rabbit ACLT osteoarthritic cartilage.

Hongbin W, Jingyuan D, Linyun C, Yuming D.

Ann Rheum Dis. 2004 Apr;63(4):369-72.

7.

Effects of calcitonin on subchondral trabecular bone changes and on osteoarthritic cartilage lesions after acute anterior cruciate ligament deficiency.

Behets C, Williams JM, Chappard D, Devogelaer JP, Manicourt DH.

J Bone Miner Res. 2004 Nov;19(11):1821-6.

9.

Intraarticular injections with methylprednisolone acetate reduce osteoarthritic lesions in parallel with chondrocyte stromelysin synthesis in experimental osteoarthritis.

Pelletier JP, Mineau F, Raynauld JP, Woessner JF Jr, Gunja-Smith Z, Martel-Pelletier J.

Arthritis Rheum. 1994 Mar;37(3):414-23.

PMID:
8129797
10.

Treatment with calcitonin suppresses the responses of bone, cartilage, and synovium in the early stages of canine experimental osteoarthritis and significantly reduces the severity of the cartilage lesions.

Manicourt DH, Altman RD, Williams JM, Devogelaer JP, Druetz-Van Egeren A, Lenz ME, Pietryla D, Thonar EJ.

Arthritis Rheum. 1999 Jun;42(6):1159-67.

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Intra-articular injections of bone morphogenetic protein-7 retard progression of existing cartilage degeneration.

Hayashi M, Muneta T, Takahashi T, Ju YJ, Tsuji K, Sekiya I.

J Orthop Res. 2010 Nov;28(11):1502-6. doi: 10.1002/jor.21165.

14.

Increased apoptosis in human osteoarthritic cartilage corresponds to reduced cell density and expression of caspase-3.

Sharif M, Whitehouse A, Sharman P, Perry M, Adams M.

Arthritis Rheum. 2004 Feb;50(2):507-15.

15.

Expression of caspase-3 and -9 relevant to cartilage destruction and chondrocyte apoptosis in human osteoarthritic cartilage.

Matsuo M, Nishida K, Yoshida A, Murakami T, Inoue H.

Acta Med Okayama. 2001 Dec;55(6):333-40.

16.

Variation patterns of two degradation enzyme systems in articular cartilage in different stages of osteoarthritis: regulation by dehydroepiandrosterone.

Bao JP, Chen WP, Feng J, Zhao J, Shi ZL, Huang K, Wu LD.

Clin Chim Acta. 2009 Oct;408(1-2):1-7. doi: 10.1016/j.cca.2009.06.040.

PMID:
19589338
17.

The apoptotic effects of oxidative stress and antiapoptotic effects of caspase inhibitors on rat notochordal cells.

Kim KW, Ha KY, Lee JS, Rhyu KW, An HS, Woo YK.

Spine (Phila Pa 1976). 2007 Oct 15;32(22):2443-8.

PMID:
18090083
18.

The effect of therapeutic ultrasound to apoptosis of chondrocyte and caspase-3 and caspase-8 expression in rabbit surgery-induced model of knee osteoarthritis.

Zeng D, Luo Q, Lin H, Zhang J, He C.

Rheumatol Int. 2012 Dec;32(12):3771-7. doi: 10.1007/s00296-011-2196-0.

PMID:
22167163
19.

Caspase-3/7 inhibition alters cell morphology in mitomycin-C treated chondrocytes.

Clements KM, Burton-Wurster N, Nuttall ME, Lust G.

J Cell Physiol. 2005 Oct;205(1):133-40.

PMID:
15828017
20.

Caspase-3 activation and induction of PARP cleavage by cyclic dipeptide cyclo(Phe-Pro) in HT-29 cells.

Brauns SC, Dealtry G, Milne P, Naudé R, Van de Venter M.

Anticancer Res. 2005 Nov-Dec;25(6B):4197-202.

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