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Activator protein-2 overexpression accounts for increased insulin receptor expression in human breast cancer.

Paonessa F, Foti D, Costa V, Chiefari E, Brunetti G, Leone F, Luciano F, Wu F, Lee AS, Gulletta E, Fusco A, Brunetti A.

Cancer Res. 2006 May 15;66(10):5085-93.


The insulin receptor: a new anticancer target for peroxisome proliferator-activated receptor-gamma (PPARgamma) and thiazolidinedione-PPARgamma agonists.

Costa V, Foti D, Paonessa F, Chiefari E, Palaia L, Brunetti G, Gulletta E, Fusco A, Brunetti A.

Endocr Relat Cancer. 2008 Mar;15(1):325-35. doi: 10.1677/ERC-07-0226.


Regulation of KiSS-1 metastasis suppressor gene expression in breast cancer cells by direct interaction of transcription factors activator protein-2alpha and specificity protein-1.

Mitchell DC, Abdelrahim M, Weng J, Stafford LJ, Safe S, Bar-Eli M, Liu M.

J Biol Chem. 2006 Jan 6;281(1):51-8. Epub 2005 Oct 27.


Estrogen receptor regulates insulin-like growth factor-I receptor gene expression in breast tumor cells: involvement of transcription factor Sp1.

Maor S, Mayer D, Yarden RI, Lee AV, Sarfstein R, Werner H, Papa MZ.

J Endocrinol. 2006 Dec;191(3):605-12.


Human KIT ligand promoter is positively regulated by HMGA1 in breast and ovarian cancer cells.

Treff NR, Dement GA, Adair JE, Britt RL, Nie R, Shima JE, Taylor WE, Reeves R.

Oncogene. 2004 Nov 4;23(52):8557-62.


HMGA1 protein is a positive regulator of the insulin-like growth factor-I receptor gene.

Aiello A, Pandini G, Sarfstein R, Werner H, Manfioletti G, Vigneri R, Belfiore A.

Eur J Cancer. 2010 Jul;46(10):1919-26. doi: 10.1016/j.ejca.2010.02.050. Epub 2010 Mar 23.


Insulin-like growth factor-I receptor (IGF-IR) translocates to nucleus and autoregulates IGF-IR gene expression in breast cancer cells.

Sarfstein R, Pasmanik-Chor M, Yeheskel A, Edry L, Shomron N, Warman N, Wertheimer E, Maor S, Shochat L, Werner H.

J Biol Chem. 2012 Jan 20;287(4):2766-76. doi: 10.1074/jbc.M111.281782. Epub 2011 Nov 29.


Ku proteins interact with activator protein-2 transcription factors and contribute to ERBB2 overexpression in breast cancer cell lines.

Nolens G, Pignon JC, Koopmansch B, Elmoualij B, Zorzi W, De Pauw E, Winkler R.

Breast Cancer Res. 2009;11(6):R83. doi: 10.1186/bcr2450. Epub 2009 Nov 11.


Transcriptional control of the human high mobility group A1 gene: basal and oncogenic Ras-regulated expression.

Cleynen I, Huysmans C, Sasazuki T, Shirasawa S, Van de Ven W, Peeters K.

Cancer Res. 2007 May 15;67(10):4620-9.


The combined immunodetection of AP-2alpha and YY1 transcription factors is associated with ERBB2 gene overexpression in primary breast tumors.

Allouche A, Nolens G, Tancredi A, Delacroix L, Mardaga J, Fridman V, Winkler R, Boniver J, Delvenne P, Begon DY.

Breast Cancer Res. 2008;10(1):R9. doi: 10.1186/bcr1851. Epub 2008 Jan 24.


Synergistic activation of the human adrenomedullin gene promoter by Sp1 and AP-2alpha.

Zhang Y, Li Y, Shibahara S, Takahashi K.

Peptides. 2008 Mar;29(3):465-72. Epub 2007 Jul 19.


Identification of target genes of transcription factor activator protein 2 gamma in breast cancer cells.

Ailan H, Xiangwen X, Daolong R, Lu G, Xiaofeng D, Xi Q, Xingwang H, Rushi L, Jian Z, Shuanglin X.

BMC Cancer. 2009 Aug 11;9:279. doi: 10.1186/1471-2407-9-279.


Repression of integrin-linked kinase by antidiabetes drugs through cross-talk of PPARγ- and AMPKα-dependent signaling: role of AP-2α and Sp1.

Hahn SS, Tang Q, Zheng F, Zhao S, Wu J, Chen J.

Cell Signal. 2014 Mar;26(3):639-47. doi: 10.1016/j.cellsig.2013.12.004. Epub 2013 Dec 20.


HMGA1 controls transcription of insulin receptor to regulate cyclin D1 translation in pancreatic cancer cells.

Kolb S, Fritsch R, Saur D, Reichert M, Schmid RM, Schneider G.

Cancer Res. 2007 May 15;67(10):4679-86.


BRCA1-Sp1 interactions in transcriptional regulation of the IGF-IR gene.

Abramovitch S, Glaser T, Ouchi T, Werner H.

FEBS Lett. 2003 Apr 24;541(1-3):149-54.


Distal ERBB2 promoter fragment displays specific transcriptional and nuclear binding activities in ERBB2 overexpressing breast cancer cells.

Delacroix L, Begon D, Chatel G, Jackers P, Winkler R.

DNA Cell Biol. 2005 Sep;24(9):582-94.


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