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Items: 1 to 20 of 402

1.

ABIN-1 binds to NEMO/IKKgamma and co-operates with A20 in inhibiting NF-kappaB.

Mauro C, Pacifico F, Lavorgna A, Mellone S, Iannetti A, Acquaviva R, Formisano S, Vito P, Leonardi A.

J Biol Chem. 2006 Jul 7;281(27):18482-8. Epub 2006 May 9.

2.

A20-binding inhibitor of nuclear factor-kappaB (NF-kappaB)-2 (ABIN-2) is an activator of inhibitor of NF-kappaB (IkappaB) kinase alpha (IKKalpha)-mediated NF-kappaB transcriptional activity.

Leotoing L, Chereau F, Baron S, Hube F, Valencia HJ, Bordereaux D, Demmers JA, Strouboulis J, Baud V.

J Biol Chem. 2011 Sep 16;286(37):32277-88. doi: 10.1074/jbc.M111.236448. Epub 2011 Jul 22.

3.

ABINs: A20 binding inhibitors of NF-kappa B and apoptosis signaling.

Verstrepen L, Carpentier I, Verhelst K, Beyaert R.

Biochem Pharmacol. 2009 Jul 15;78(2):105-14. doi: 10.1016/j.bcp.2009.02.009. Epub 2009 Feb 27. Review.

PMID:
19464428
4.

Identification of a novel A20-binding inhibitor of nuclear factor-kappa B activation termed ABIN-2.

Van Huffel S, Delaei F, Heyninck K, De Valck D, Beyaert R.

J Biol Chem. 2001 Aug 10;276(32):30216-23. Epub 2001 Jun 4.

5.
7.

A20-mediated negative regulation of canonical NF-κB signaling pathway.

Pujari R, Hunte R, Khan WN, Shembade N.

Immunol Res. 2013 Dec;57(1-3):166-71. doi: 10.1007/s12026-013-8463-2. Review.

PMID:
24242761
8.

Structure-function analysis of the A20-binding inhibitor of NF-kappa B activation, ABIN-1.

Heyninck K, Kreike MM, Beyaert R.

FEBS Lett. 2003 Feb 11;536(1-3):135-40.

9.

A bacterial E3 ubiquitin ligase IpaH9.8 targets NEMO/IKKgamma to dampen the host NF-kappaB-mediated inflammatory response.

Ashida H, Kim M, Schmidt-Supprian M, Ma A, Ogawa M, Sasakawa C.

Nat Cell Biol. 2010 Jan;12(1):66-73; sup pp 1-9. doi: 10.1038/ncb2006. Epub 2009 Dec 13.

10.

Recruitment of A20 by the C-terminal domain of NEMO suppresses NF-κB activation and autoinflammatory disease.

Zilberman-Rudenko J, Shawver LM, Wessel AW, Luo Y, Pelletier M, Tsai WL, Lee Y, Vonortas S, Cheng L, Ashwell JD, Orange JS, Siegel RM, Hanson EP.

Proc Natl Acad Sci U S A. 2016 Feb 9;113(6):1612-7. doi: 10.1073/pnas.1518163113. Epub 2016 Jan 22.

11.

Ubiquitin binding mediates the NF-kappaB inhibitory potential of ABIN proteins.

Wagner S, Carpentier I, Rogov V, Kreike M, Ikeda F, Löhr F, Wu CJ, Ashwell JD, Dötsch V, Dikic I, Beyaert R.

Oncogene. 2008 Jun 12;27(26):3739-45. doi: 10.1038/sj.onc.1211042. Epub 2008 Jan 21.

PMID:
18212736
12.

NEMO-binding domains of both IKKalpha and IKKbeta regulate IkappaB kinase complex assembly and classical NF-kappaB activation.

Solt LA, Madge LA, May MJ.

J Biol Chem. 2009 Oct 2;284(40):27596-608. doi: 10.1074/jbc.M109.047563. Epub 2009 Aug 7.

14.

The biology of A20-binding inhibitors of NF-kappaB activation (ABINs).

Verstrepen L, Carpentier I, Beyaert R.

Adv Exp Med Biol. 2014;809:13-31. Review.

PMID:
25302363
15.

ATM- and NEMO-dependent ELKS ubiquitination coordinates TAK1-mediated IKK activation in response to genotoxic stress.

Wu ZH, Wong ET, Shi Y, Niu J, Chen Z, Miyamoto S, Tergaonkar V.

Mol Cell. 2010 Oct 8;40(1):75-86. doi: 10.1016/j.molcel.2010.09.010.

16.

Novel non-peptide small molecules preventing IKKβ/NEMO association inhibit NF-κB activation in LPS-stimulated J774 macrophages.

De Falco F, Di Giovanni C, Cerchia C, De Stefano D, Capuozzo A, Irace C, Iuvone T, Santamaria R, Carnuccio R, Lavecchia A.

Biochem Pharmacol. 2016 Mar 15;104:83-94. doi: 10.1016/j.bcp.2016.01.008. Epub 2016 Jan 14.

PMID:
26776306
17.

Direct, noncatalytic mechanism of IKK inhibition by A20.

Skaug B, Chen J, Du F, He J, Ma A, Chen ZJ.

Mol Cell. 2011 Nov 18;44(4):559-71. doi: 10.1016/j.molcel.2011.09.015.

18.

Functional redundancy of the zinc fingers of A20 for inhibition of NF-kappaB activation and protein-protein interactions.

Klinkenberg M, Van Huffel S, Heyninck K, Beyaert R.

FEBS Lett. 2001 Jun 1;498(1):93-7.

19.

Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected].

Wu CJ, Conze DB, Li T, Srinivasula SM, Ashwell JD.

Nat Cell Biol. 2006 Apr;8(4):398-406. Epub 2006 Mar 19. Erratum in: Nat Cell Biol. 2006 Apr;8(4):424.

PMID:
16547522
20.

Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-κB regulation.

Tokunaga F, Nishimasu H, Ishitani R, Goto E, Noguchi T, Mio K, Kamei K, Ma A, Iwai K, Nureki O.

EMBO J. 2012 Oct 3;31(19):3856-70. doi: 10.1038/emboj.2012.241. Epub 2012 Aug 28.

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