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Items: 1 to 20 of 607

1.

Exaggerated behavioral phenotypes in Fmr1/Fxr2 double knockout mice reveal a functional genetic interaction between Fragile X-related proteins.

Spencer CM, Serysheva E, Yuva-Paylor LA, Oostra BA, Nelson DL, Paylor R.

Hum Mol Genet. 2006 Jun 15;15(12):1984-94. Epub 2006 May 4.

PMID:
16675531
2.

Knockout mouse model for Fxr2: a model for mental retardation.

Bontekoe CJ, McIlwain KL, Nieuwenhuizen IM, Yuva-Paylor LA, Nellis A, Willemsen R, Fang Z, Kirkpatrick L, Bakker CE, McAninch R, Cheng NC, Merriweather M, Hoogeveen AT, Nelson D, Paylor R, Oostra BA.

Hum Mol Genet. 2002 Mar 1;11(5):487-98.

PMID:
11875043
3.

Male and female Fmr1 knockout mice on C57 albino background exhibit spatial learning and memory impairments.

Baker KB, Wray SP, Ritter R, Mason S, Lanthorn TH, Savelieva KV.

Genes Brain Behav. 2010 Aug;9(6):562-74. doi: 10.1111/j.1601-183X.2010.00585.x. Epub 2010 Apr 6.

4.

Altered anxiety-related and social behaviors in the Fmr1 knockout mouse model of fragile X syndrome.

Spencer CM, Alekseyenko O, Serysheva E, Yuva-Paylor LA, Paylor R.

Genes Brain Behav. 2005 Oct;4(7):420-30.

5.

Alterations in the auditory startle response in Fmr1 targeted mutant mouse models of fragile X syndrome.

Nielsen DM, Derber WJ, McClellan DA, Crnic LS.

Brain Res. 2002 Feb 8;927(1):8-17.

PMID:
11814427
6.

Reduction of BDNF expression in Fmr1 knockout mice worsens cognitive deficits but improves hyperactivity and sensorimotor deficits.

Uutela M, Lindholm J, Louhivuori V, Wei H, Louhivuori LM, Pertovaara A, Akerman K, Castrén E, Castrén ML.

Genes Brain Behav. 2012 Jul;11(5):513-23. doi: 10.1111/j.1601-183X.2012.00784.x. Epub 2012 Apr 11.

7.

Fmr1 knockout mice are impaired in a leverpress escape/avoidance task.

Brennan FX, Albeck DS, Paylor R.

Genes Brain Behav. 2006 Aug;5(6):467-71.

8.

Social behavior in Fmr1 knockout mice carrying a human FMR1 transgene.

Spencer CM, Graham DF, Yuva-Paylor LA, Nelson DL, Paylor R.

Behav Neurosci. 2008 Jun;122(3):710-5. doi: 10.1037/0735-7044.122.3.710.

PMID:
18513141
9.

Altered hippocampal synaptic plasticity in the FMR1 gene family knockout mouse models.

Zhang J, Hou L, Klann E, Nelson DL.

J Neurophysiol. 2009 May;101(5):2572-80. doi: 10.1152/jn.90558.2008. Epub 2009 Feb 25.

10.

Reversal of sensorimotor gating abnormalities in Fmr1 knockout mice carrying a human Fmr1 transgene.

Paylor R, Yuva-Paylor LA, Nelson DL, Spencer CM.

Behav Neurosci. 2008 Dec;122(6):1371-7. doi: 10.1037/a0013047.

PMID:
19045956
11.

Immunocytochemical and biochemical characterization of FMRP, FXR1P, and FXR2P in the mouse.

Bakker CE, de Diego Otero Y, Bontekoe C, Raghoe P, Luteijn T, Hoogeveen AT, Oostra BA, Willemsen R.

Exp Cell Res. 2000 Jul 10;258(1):162-70.

PMID:
10912798
12.

Oligomerization properties of fragile-X mental-retardation protein (FMRP) and the fragile-X-related proteins FXR1P and FXR2P.

Tamanini F, Van Unen L, Bakker C, Sacchi N, Galjaard H, Oostra BA, Hoogeveen AT.

Biochem J. 1999 Nov 1;343 Pt 3:517-23.

13.

Expression of three zebrafish orthologs of human FMR1-related genes and their phylogenetic relationships.

Tucker B, Richards R, Lardelli M.

Dev Genes Evol. 2004 Nov;214(11):567-74. Epub 2004 Sep 17.

PMID:
15378363
14.

Sensorimotor gating abnormalities in young males with fragile X syndrome and Fmr1-knockout mice.

Frankland PW, Wang Y, Rosner B, Shimizu T, Balleine BW, Dykens EM, Ornitz EM, Silva AJ.

Mol Psychiatry. 2004 Apr;9(4):417-25.

PMID:
14981523
15.

(Over)correction of FMR1 deficiency with YAC transgenics: behavioral and physical features.

Peier AM, McIlwain KL, Kenneson A, Warren ST, Paylor R, Nelson DL.

Hum Mol Genet. 2000 May 1;9(8):1145-59.

PMID:
10767339
16.

Fxr1 knockout mice show a striated muscle phenotype: implications for Fxr1p function in vivo.

Mientjes EJ, Willemsen R, Kirkpatrick LL, Nieuwenhuizen IM, Hoogeveen-Westerveld M, Verweij M, Reis S, Bardoni B, Hoogeveen AT, Oostra BA, Nelson DL.

Hum Mol Genet. 2004 Jul 1;13(13):1291-302. Epub 2004 May 5.

PMID:
15128702
17.

Fragile X-related proteins regulate mammalian circadian behavioral rhythms.

Zhang J, Fang Z, Jud C, Vansteensel MJ, Kaasik K, Lee CC, Albrecht U, Tamanini F, Meijer JH, Oostra BA, Nelson DL.

Am J Hum Genet. 2008 Jul;83(1):43-52. doi: 10.1016/j.ajhg.2008.06.003. Epub 2008 Jun 26.

18.

Two members of the Fxr gene family, Fmr1 and Fxr1, are differentially expressed in Xenopus tropicalis.

Blonden L, van 't Padje S, Severijnen LA, Destree O, Oostra BA, Willemsen R.

Int J Dev Biol. 2005;49(4):437-41.

19.

Alternative splicing in the murine and human FXR1 genes.

Kirkpatrick LL, McIlwain KA, Nelson DL.

Genomics. 1999 Jul 15;59(2):193-202.

PMID:
10409431
20.

Expression of FMR1, FXR1, and FXR2 genes in human prenatal tissues.

Agulhon C, Blanchet P, Kobetz A, Marchant D, Faucon N, Sarda P, Moraine C, Sittler A, Biancalana V, Malafosse A, Abitbol M.

J Neuropathol Exp Neurol. 1999 Aug;58(8):867-80.

PMID:
10446811

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