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Items: 1 to 20 of 172

1.

Broad therapeutic treatment window of [Nle(4), D-Phe(7)]alpha-melanocyte-stimulating hormone for long-lasting protection against ischemic stroke, in Mongolian gerbils.

Giuliani D, Leone S, Mioni C, Bazzani C, Zaffe D, Botticelli AR, Altavilla D, Galantucci M, Minutoli L, Bitto A, Squadrito F, Guarini S.

Eur J Pharmacol. 2006 May 24;538(1-3):48-56. Epub 2006 Mar 24.

PMID:
16647700
2.

Functional recovery after delayed treatment of ischemic stroke with melanocortins is associated with overexpression of the activity-dependent gene Zif268.

Giuliani D, Ottani A, Minutoli L, Stefano VD, Galantucci M, Bitto A, Zaffe D, Altavilla D, Botticelli AR, Squadrito F, Guarini S.

Brain Behav Immun. 2009 Aug;23(6):844-50. doi: 10.1016/j.bbi.2009.03.009. Epub 2009 Apr 5.

PMID:
19345727
3.

Neuroprotection in focal cerebral ischemia owing to delayed treatment with melanocortins.

Giuliani D, Ottani A, Mioni C, Bazzani C, Galantucci M, Minutoli L, Bitto A, Zaffe D, Botticelli AR, Squadrito F, Guarini S.

Eur J Pharmacol. 2007 Sep 10;570(1-3):57-65. Epub 2007 Jun 5.

PMID:
17588564
4.

Treatment of cerebral ischemia with melanocortins acting at MC4 receptors induces marked neurogenesis and long-lasting functional recovery.

Giuliani D, Zaffe D, Ottani A, Spaccapelo L, Galantucci M, Minutoli L, Bitto A, Irrera N, Contri M, Altavilla D, Botticelli AR, Squadrito F, Guarini S.

Acta Neuropathol. 2011 Oct;122(4):443-53. doi: 10.1007/s00401-011-0873-4. Epub 2011 Sep 17.

PMID:
21927944
5.

Melanocortin MC₄ receptor agonists counteract late inflammatory and apoptotic responses and improve neuronal functionality after cerebral ischemia.

Spaccapelo L, Bitto A, Galantucci M, Ottani A, Irrera N, Minutoli L, Altavilla D, Novellino E, Grieco P, Zaffe D, Squadrito F, Giuliani D, Guarini S.

Eur J Pharmacol. 2011 Nov 30;670(2-3):479-86. doi: 10.1016/j.ejphar.2011.09.015. Epub 2011 Sep 21.

PMID:
21946115
6.

Up-regulation of the canonical Wnt-3A and Sonic hedgehog signaling underlies melanocortin-induced neurogenesis after cerebral ischemia.

Spaccapelo L, Galantucci M, Neri L, Contri M, Pizzala R, D'Amico R, Ottani A, Sandrini M, Zaffe D, Giuliani D, Guarini S.

Eur J Pharmacol. 2013 May 5;707(1-3):78-86. doi: 10.1016/j.ejphar.2013.03.030. Epub 2013 Mar 25.

PMID:
23535605
7.

Both early and delayed treatment with melanocortin 4 receptor-stimulating melanocortins produces neuroprotection in cerebral ischemia.

Giuliani D, Mioni C, Altavilla D, Leone S, Bazzani C, Minutoli L, Bitto A, Cainazzo MM, Marini H, Zaffe D, Botticelli AR, Pizzala R, Savio M, Necchi D, Schiöth HB, Bertolini A, Squadrito F, Guarini S.

Endocrinology. 2006 Mar;147(3):1126-35. Epub 2005 Oct 27.

PMID:
16254026
8.

Vagus nerve mediates the protective effects of melanocortins against cerebral and systemic damage after ischemic stroke.

Ottani A, Giuliani D, Mioni C, Galantucci M, Minutoli L, Bitto A, Altavilla D, Zaffe D, Botticelli AR, Squadrito F, Guarini S.

J Cereb Blood Flow Metab. 2009 Mar;29(3):512-23. doi: 10.1038/jcbfm.2008.140. Epub 2008 Nov 19.

PMID:
19018269
9.

Further evidence that melanocortins prevent myocardial reperfusion injury by activating melanocortin MC3 receptors.

Mioni C, Giuliani D, Cainazzo MM, Leone S, Bazzani C, Grieco P, Novellino E, Tomasi A, Bertolini A, Guarini S.

Eur J Pharmacol. 2003 Sep 23;477(3):227-34. Erratum in: Eur J Pharmacol. 2004 Feb 20;486(2):237. Iannone C [corrected to Iannone A].

PMID:
14522361
10.

Melanocortins protect against brain damage and counteract cognitive decline in a transgenic mouse model of moderate Alzheimer׳s disease.

Giuliani D, Galantucci M, Neri L, Canalini F, Calevro A, Bitto A, Ottani A, Vandini E, Sena P, Sandrini M, Squadrito F, Zaffe D, Guarini S.

Eur J Pharmacol. 2014 Oct 5;740:144-50. doi: 10.1016/j.ejphar.2014.06.063. Epub 2014 Jul 15.

PMID:
25034807
11.

Protective effect of melanocortin peptides in rat myocardial ischemia.

Bazzani C, Guarini S, Botticelli AR, Zaffe D, Tomasi A, Bini A, Cainazzo MM, Ferrazza G, Mioni C, Bertolini A.

J Pharmacol Exp Ther. 2001 Jun;297(3):1082-7.

12.

Melanocortin 4 receptor activation protects against testicular ischemia-reperfusion injury by triggering the cholinergic antiinflammatory pathway.

Minutoli L, Bitto A, Squadrito F, Irrera N, Rinaldi M, Nicotina PA, Arena S, Magno C, Marini H, Spaccapelo L, Ottani A, Giuliani D, Romeo C, Guarini S, Antonuccio P, Altavilla D.

Endocrinology. 2011 Oct;152(10):3852-61. doi: 10.1210/en.2011-1016. Epub 2011 Aug 9.

13.

alpha-Melanocyte-stimulating hormone is neuroprotective in rat global cerebral ischemia.

Forslin Aronsson S, Spulber S, Popescu LM, Winblad B, Post C, Oprica M, Schultzberg M.

Neuropeptides. 2006 Feb;40(1):65-75. Epub 2006 Jan 18.

PMID:
16414116
14.

NDP-α-MSH induces intense neurogenesis and cognitive recovery in Alzheimer transgenic mice through activation of melanocortin MC4 receptors.

Giuliani D, Neri L, Canalini F, Calevro A, Ottani A, Vandini E, Sena P, Zaffe D, Guarini S.

Mol Cell Neurosci. 2015 Jul;67:13-21. doi: 10.1016/j.mcn.2015.05.004. Epub 2015 May 21.

PMID:
26003413
15.

α-Melanocyte-stimulating hormone (α-MSH) reverses impairment of memory reconsolidation induced by interleukin-1 beta (IL-1 beta) hippocampal infusions.

Machado I, González P, Schiöth HB, Lasaga M, Scimonelli TN.

Peptides. 2010 Nov;31(11):2141-4. doi: 10.1016/j.peptides.2010.07.018. Epub 2010 Aug 3.

PMID:
20688120
16.

Protective effects of melanocortins on short-term changes in a rat model of traumatic brain injury*.

Bitto A, Polito F, Irrera N, Calò M, Spaccapelo L, Marini HR, Giuliani D, Ottani A, Rinaldi M, Minutoli L, Guarini S, Squadrito F, Altavilla D.

Crit Care Med. 2012 Mar;40(3):945-51. doi: 10.1097/CCM.0b013e318236efde.

PMID:
22036855
17.

[The protective effects of melatonin on global cerebral ischemia-reperfusion injury in gerbils].

Zhang J, Guo JD, Xing SH, Gu SL, Dai TJ.

Yao Xue Xue Bao. 2002 May;37(5):329-33. Chinese.

PMID:
12579834
18.

Participation of alpha-melanocyte stimulating hormone in ethanol-induced anxiolysis and withdrawal anxiety in rats.

Kokare DM, Chopde CT, Subhedar NK.

Neuropharmacology. 2006 Sep;51(3):536-45. Epub 2006 Jun 8.

PMID:
16762375
19.

Hemodynamic actions and mechanisms of systemically administered α-MSH analogs in mice.

Rinne P, Tikka S, Mäkelä S, Streng T, Savontaus E.

Peptides. 2012 Nov;38(1):150-8. doi: 10.1016/j.peptides.2012.09.004. Epub 2012 Sep 11.

PMID:
22982611
20.

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