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Items: 1 to 20 of 147

1.

Intracellular domains of amyloid precursor-like protein 2 interact with CP2 transcription factor in the nucleus and induce glycogen synthase kinase-3beta expression.

Xu Y, Kim HS, Joo Y, Choi Y, Chang KA, Park CH, Shin KY, Kim S, Cheon YH, Baik TK, Kim JH, Suh YH.

Cell Death Differ. 2007 Jan;14(1):79-91. Epub 2006 Apr 28.

2.

C-terminal fragments of amyloid precursor protein exert neurotoxicity by inducing glycogen synthase kinase-3beta expression.

Kim HS, Kim EM, Lee JP, Park CH, Kim S, Seo JH, Chang KA, Yu E, Jeong SJ, Chong YH, Suh YH.

FASEB J. 2003 Oct;17(13):1951-3. Epub 2003 Aug 15.

PMID:
12923068
3.

Phosphorylation of amyloid precursor protein (APP) at Thr668 regulates the nuclear translocation of the APP intracellular domain and induces neurodegeneration.

Chang KA, Kim HS, Ha TY, Ha JW, Shin KY, Jeong YH, Lee JP, Park CH, Kim S, Baik TK, Suh YH.

Mol Cell Biol. 2006 Jun;26(11):4327-38.

4.

Interaction of Tau with Fe65 links tau to APP.

Barbato C, Canu N, Zambrano N, Serafino A, Minopoli G, Ciotti MT, Amadoro G, Russo T, Calissano P.

Neurobiol Dis. 2005 Mar;18(2):399-408.

PMID:
15686969
5.

Turnover of amyloid precursor protein family members determines their nuclear signaling capability.

Gersbacher MT, Goodger ZV, Trutzel A, Bundschuh D, Nitsch RM, Konietzko U.

PLoS One. 2013 Jul 18;8(7):e69363. doi: 10.1371/journal.pone.0069363. Print 2013.

6.

gamma-Secretase cleavage and binding to FE65 regulate the nuclear translocation of the intracellular C-terminal domain (ICD) of the APP family of proteins.

Walsh DM, Fadeeva JV, LaVoie MJ, Paliga K, Eggert S, Kimberly WT, Wasco W, Selkoe DJ.

Biochemistry. 2003 Jun 10;42(22):6664-73.

PMID:
12779321
7.

Processing of beta-amyloid precursor-like protein-1 and -2 by gamma-secretase regulates transcription.

Scheinfeld MH, Ghersi E, Laky K, Fowlkes BJ, D'Adamio L.

J Biol Chem. 2002 Nov 15;277(46):44195-201. Epub 2002 Sep 12.

8.

Valproic Acid Modifies Synaptic Structure and Accelerates Neurite Outgrowth Via the Glycogen Synthase Kinase-3β Signaling Pathway in an Alzheimer's Disease Model.

Long ZM, Zhao L, Jiang R, Wang KJ, Luo SF, Zheng M, Li XF, He GQ.

CNS Neurosci Ther. 2015 Nov;21(11):887-97. doi: 10.1111/cns.12445. Epub 2015 Sep 19.

PMID:
26385876
10.

Dishevelled regulates the metabolism of amyloid precursor protein via protein kinase C/mitogen-activated protein kinase and c-Jun terminal kinase.

Mudher A, Chapman S, Richardson J, Asuni A, Gibb G, Pollard C, Killick R, Iqbal T, Raymond L, Varndell I, Sheppard P, Makoff A, Gower E, Soden PE, Lewis P, Murphy M, Golde TE, Rupniak HT, Anderton BH, Lovestone S.

J Neurosci. 2001 Jul 15;21(14):4987-95.

11.
12.

Roles of glycogen synthase kinase 3 in Alzheimer's disease.

Cai Z, Zhao Y, Zhao B.

Curr Alzheimer Res. 2012 Sep;9(7):864-79. Review.

PMID:
22272620
13.

Down-regulation of WW domain-containing oxidoreductase induces Tau phosphorylation in vitro. A potential role in Alzheimer's disease.

Sze CI, Su M, Pugazhenthi S, Jambal P, Hsu LJ, Heath J, Schultz L, Chang NS.

J Biol Chem. 2004 Jul 16;279(29):30498-506. Epub 2004 May 4.

14.
15.

Alterations of cyclin dependent kinase 5 expression and phosphorylation in amyloid precursor protein (APP)-transfected PC12 cells.

Czapski GA, Gąssowska M, Songin M, Radecka UD, Strosznajder JB.

FEBS Lett. 2011 Apr 20;585(8):1243-8. doi: 10.1016/j.febslet.2011.03.058. Epub 2011 Mar 30.

16.

Alleviating the suppression of glycogen synthase kinase-3beta by Akt leads to the phosphorylation of cAMP-response element-binding protein and its transactivation in intact cell nuclei.

Salas TR, Reddy SA, Clifford JL, Davis RJ, Kikuchi A, Lippman SM, Menter DG.

J Biol Chem. 2003 Oct 17;278(42):41338-46. Epub 2003 Aug 4.

17.

Disabled-1 binds to the cytoplasmic domain of amyloid precursor-like protein 1.

Homayouni R, Rice DS, Sheldon M, Curran T.

J Neurosci. 1999 Sep 1;19(17):7507-15.

19.

The Fe65 adaptor protein interacts through its PID1 domain with the transcription factor CP2/LSF/LBP1.

Zambrano N, Minopoli G, de Candia P, Russo T.

J Biol Chem. 1998 Aug 7;273(32):20128-33.

20.

Cleavage of amyloid-beta precursor protein and amyloid-beta precursor-like protein by BACE 1.

Li Q, Südhof TC.

J Biol Chem. 2004 Mar 12;279(11):10542-50. Epub 2003 Dec 29.

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