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Items: 1 to 20 of 86

1.

Notch 1 activation in the molecular pathogenesis of T-cell acute lymphoblastic leukaemia.

Grabher C, von Boehmer H, Look AT.

Nat Rev Cancer. 2006 May;6(5):347-59. Review.

PMID:
16612405
2.
3.

Kick it up a Notch: NOTCH1 activation in T-ALL.

Gridley T.

Cancer Cell. 2004 Nov;6(5):431-2.

4.
5.

Differential regulation of Notch signal transduction in leukaemia and lymphoma cells in culture.

Chiaramonte R, Calzavara E, Balordi F, Sabbadini M, Capello D, Gaidano G, Serra A, Comi P, Sherbet GV.

J Cell Biochem. 2003 Feb 15;88(3):569-77.

PMID:
12532332
6.

CUTLL1, a novel human T-cell lymphoma cell line with t(7;9) rearrangement, aberrant NOTCH1 activation and high sensitivity to gamma-secretase inhibitors.

Palomero T, Barnes KC, Real PJ, Glade Bender JL, Sulis ML, Murty VV, Colovai AI, Balbin M, Ferrando AA.

Leukemia. 2006 Jul;20(7):1279-87. Epub 2006 May 11.

PMID:
16688224
7.

NOTCH1 mutations in T-cell acute lymphoblastic leukemia: prognostic significance and implication in multifactorial leukemogenesis.

Zhu YM, Zhao WL, Fu JF, Shi JY, Pan Q, Hu J, Gao XD, Chen B, Li JM, Xiong SM, Gu LJ, Tang JY, Liang H, Jiang H, Xue YQ, Shen ZX, Chen Z, Chen SJ.

Clin Cancer Res. 2006 May 15;12(10):3043-9. Erratum in: Clin Cancer Res. 2009 Feb 15;15(4):1506.

8.

Notch signaling induces SKP2 expression and promotes reduction of p27Kip1 in T-cell acute lymphoblastic leukemia cell lines.

Dohda T, Maljukova A, Liu L, Heyman M, Grandér D, Brodin D, Sangfelt O, Lendahl U.

Exp Cell Res. 2007 Aug 15;313(14):3141-52. Epub 2007 May 5.

PMID:
17560996
9.

Development of Notch-dependent T-cell leukemia by deregulated Rap1 signaling.

Wang SF, Aoki M, Nakashima Y, Shinozuka Y, Tanaka H, Taniwaki M, Hattori M, Minato N.

Blood. 2008 Mar 1;111(5):2878-86. doi: 10.1182/blood-2007-07-103119. Epub 2008 Jan 7.

10.

Distinct gene expression profiles of acute myeloid/T-lymphoid leukemia with silenced CEBPA and mutations in NOTCH1.

Wouters BJ, Jordà MA, Keeshan K, Louwers I, Erpelinck-Verschueren CA, Tielemans D, Langerak AW, He Y, Yashiro-Ohtani Y, Zhang P, Hetherington CJ, Verhaak RG, Valk PJ, Löwenberg B, Tenen DG, Pear WS, Delwel R.

Blood. 2007 Nov 15;110(10):3706-14. Epub 2007 Aug 1.

11.

Notch in T-ALL: new players in a complex disease.

Koch U, Radtke F.

Trends Immunol. 2011 Sep;32(9):434-42. doi: 10.1016/j.it.2011.06.005. Epub 2011 Jul 19. Review.

PMID:
21775206
12.

NOTCH and PI3K-AKT pathways intertwined.

Gutierrez A, Look AT.

Cancer Cell. 2007 Nov;12(5):411-3.

13.

NOTCH is a key regulator of human T-cell acute leukemia initiating cell activity.

Armstrong F, Brunet de la Grange P, Gerby B, Rouyez MC, Calvo J, Fontenay M, Boissel N, Dombret H, Baruchel A, Landman-Parker J, Roméo PH, Ballerini P, Pflumio F.

Blood. 2009 Feb 19;113(8):1730-40. doi: 10.1182/blood-2008-02-138172. Epub 2008 Nov 4.

14.

Bone marrow stromal cells and the upregulation of interleukin-8 production in human T-cell acute lymphoblastic leukemia through the CXCL12/CXCR4 axis and the NF-kappaB and JNK/AP-1 pathways.

Scupoli MT, Donadelli M, Cioffi F, Rossi M, Perbellini O, Malpeli G, Corbioli S, Vinante F, Krampera M, Palmieri M, Scarpa A, Ariola C, Foà R, Pizzolo G.

Haematologica. 2008 Apr;93(4):524-32. doi: 10.3324/haematol.12098. Epub 2008 Mar 5.

15.

Targeting promiscuous signaling pathways in cancer: another Notch in the bedpost.

Beverly LJ, Capobianco AJ.

Trends Mol Med. 2004 Dec;10(12):591-8. Review.

PMID:
15567329
16.

NOTCH1-induced T-cell leukemia in transgenic zebrafish.

Chen J, Jette C, Kanki JP, Aster JC, Look AT, Griffin JD.

Leukemia. 2007 Mar;21(3):462-71. Epub 2007 Jan 25.

PMID:
17252014
17.

Survival signaling by Notch1: mammalian target of rapamycin (mTOR)-dependent inhibition of p53.

Mungamuri SK, Yang X, Thor AD, Somasundaram K.

Cancer Res. 2006 May 1;66(9):4715-24.

18.

Mutations in the HD and PEST domain of Notch-1 receptor in T-cell acute lymphoblastic leukemia: report of novel mutations from Indian population.

Bhanushali AA, Babu S, Thangapandi VR, Pillai R, Chheda P, Das BR.

Oncol Res. 2010;19(2):99-104.

PMID:
21302811
19.

NOTCH1 mutation can be an early, prenatal genetic event in T-ALL.

Eguchi-Ishimae M, Eguchi M, Kempski H, Greaves M.

Blood. 2008 Jan 1;111(1):376-8. Epub 2007 Sep 27.

20.

[Functional analysis of notch in the pathophysiology of leukemia].

Tohda S.

Rinsho Byori. 2009 Apr;57(4):351-6. Review. Japanese.

PMID:
19489437

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