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Items: 1 to 20 of 366

1.

Pharmacogenetics of thiopurine therapy in paediatric IBD patients.

De Ridder L, Van Dieren JM, Van Deventer HJ, Stokkers PC, Van der Woude JC, Van Vuuren AJ, Benninga MA, Escher JC, Hommes DW.

Aliment Pharmacol Ther. 2006 Apr 15;23(8):1137-41.

2.

Thiopurine S-methyltransferase genotype and the use of thiopurines in paediatric inflammatory bowel disease Greek patients.

Gazouli M, Pachoula I, Panayotou I, Mantzaris G, Syriopoulou VP, Goutas N, Vlachodimitropoulos D, Anagnou NP, Roma-Giannikou E.

J Clin Pharm Ther. 2010 Feb;35(1):93-7. doi: 10.1111/j.1365-2710.2009.01041.x.

PMID:
20175817
3.

Pharmacogenetic association with adverse drug reactions to azathioprine immunosuppressive therapy following liver transplantation.

Breen DP, Marinaki AM, Arenas M, Hayes PC.

Liver Transpl. 2005 Jul;11(7):826-33. Erratum in: Liver Transpl. 2005 Sep;11(9):1150.

4.

Adverse drug reactions to azathioprine therapy are associated with polymorphism in the gene encoding inosine triphosphate pyrophosphatase (ITPase).

Marinaki AM, Ansari A, Duley JA, Arenas M, Sumi S, Lewis CM, Shobowale-Bakre el-M, Escuredo E, Fairbanks LD, Sanderson JD.

Pharmacogenetics. 2004 Mar;14(3):181-7.

PMID:
15167706
5.

Inosine triphosphate pyrophosphatase and thiopurine s-methyltransferase genotypes relationship to azathioprine-induced myelosuppression.

Zelinkova Z, Derijks LJ, Stokkers PC, Vogels EW, van Kampen AH, Curvers WL, Cohn D, van Deventer SJ, Hommes DW.

Clin Gastroenterol Hepatol. 2006 Jan;4(1):44-9.

PMID:
16431304
6.

Association of inosine triphosphatase 94C>A and thiopurine S-methyltransferase deficiency with adverse events and study drop-outs under azathioprine therapy in a prospective Crohn disease study.

von Ahsen N, Armstrong VW, Behrens C, von Tirpitz C, Stallmach A, Herfarth H, Stein J, Bias P, Adler G, Shipkova M, Oellerich M, Kruis W, Reinshagen M, Schütz E.

Clin Chem. 2005 Dec;51(12):2282-8. Epub 2005 Oct 7. Erratum in: Clin Chem. 2006 Aug;52(8):1628. Schütz, Ekkehard [added].

7.

Allele frequency of thiopurine methyltransferase and inosine triphosphate pyrophosphatase gene polymorphisms in Korean patients with inflammatory bowel diseases.

Cheon JH, Kim JH, Kim BY, Kim SW, Hong SY, Eun CS, Hong SS, Byeon JS, Kim TI, Han DS, Yang SK, Lee KR, Kim WH.

Hepatogastroenterology. 2009 Mar-Apr;56(90):421-3.

PMID:
19579612
8.

Lack of association between the ITPA 94C>A polymorphism and adverse effects from azathioprine.

Gearry RB, Roberts RL, Barclay ML, Kennedy MA.

Pharmacogenetics. 2004 Nov;14(11):779-81.

PMID:
15564886
9.

A pharmacogenetics study of TPMT and ITPA genes detects a relationship with side effects and clinical response in patients with inflammatory bowel disease receiving Azathioprine.

Zabala-Fernández W, Barreiro-de Acosta M, Echarri A, Carpio D, Lorenzo A, Castro J, Martínez-Ares D, Pereira S, Martin-Granizo I, Corton M, Carracedo A, Barros F.

J Gastrointestin Liver Dis. 2011 Sep;20(3):247-53.

10.

Thiopurine methyltransferase gene polymorphisms in Chinese patients with inflammatory bowel disease.

Cao Q, Zhu Q, Shang Y, Gao M, Si J.

Digestion. 2009;79(1):58-63. doi: 10.1159/000205268. Epub 2009 Feb 28.

PMID:
19252404
11.

TPMT and ITPA genetic variants in Lithuanian inflammatory bowel disease patients: Prevalence and azathioprine-related side effects.

Steponaitiene R, Kupcinskas J, Survilaite S, Varkalaite G, Jonaitis L, Kiudelis G, Denapiene G, Valantinas J, Skieceviciene J, Kupcinskas L.

Adv Med Sci. 2016 Mar;61(1):135-40. doi: 10.1016/j.advms.2015.09.008. Epub 2015 Dec 10.

PMID:
26674571
12.

Thiopurine S-methyltransferase (TPMT) genotype does not predict adverse drug reactions to thiopurine drugs in patients with inflammatory bowel disease.

Gearry RB, Barclay ML, Burt MJ, Collett JA, Chapman BA, Roberts RL, Kennedy MA.

Aliment Pharmacol Ther. 2003 Aug 15;18(4):395-400.

13.

The impact of thiopurine s-methyltransferase polymorphism on azathioprine-induced myelotoxicity in renal transplant recipients.

Kurzawski M, Dziewanowski K, Gawrońska-Szklarz B, Domański L, Droździk M.

Ther Drug Monit. 2005 Aug;27(4):435-41.

PMID:
16044099
14.

Glutathione-S-transferase genotypes and the adverse effects of azathioprine in young patients with inflammatory bowel disease.

Stocco G, Martelossi S, Barabino A, Decorti G, Bartoli F, Montico M, Gotti A, Ventura A.

Inflamm Bowel Dis. 2007 Jan;13(1):57-64.

PMID:
17206640
15.

Correlation of genotypes for thiopurine methyltransferase and inosine triphosphate pyrophosphatase with long-term clinical outcomes in Korean patients with inflammatory bowel diseases during treatment with thiopurine drugs.

Jung YS, Cheon JH, Park JJ, Moon CM, Kim ES, Lee JH, Kim SW, Kim JH, Hong SP, Kim TI, Kim WH.

J Hum Genet. 2010 Feb;55(2):121-3. doi: 10.1038/jhg.2009.125. Epub 2009 Dec 4.

PMID:
19960028
16.

Azathioprine therapy and adverse drug reactions in patients with inflammatory bowel disease: impact of thiopurine S-methyltransferase polymorphism.

Schwab M, Schäffeler E, Marx C, Fischer C, Lang T, Behrens C, Gregor M, Eichelbaum M, Zanger UM, Kaskas BA.

Pharmacogenetics. 2002 Aug;12(6):429-36.

PMID:
12172211
17.

No induction of thiopurine methyltransferase during thiopurine treatment in inflammatory bowel disease.

Lindqvist M, Hindorf U, Almer S, Söderkvist P, Ström M, Hjortswang H, Peterson C.

Nucleosides Nucleotides Nucleic Acids. 2006;25(9-11):1033-7.

PMID:
17065060
18.

Should thiopurine methyltransferase genotypes and phenotypes be measured before thiopurine therapy in patients with inflammatory bowel disease?

Fangbin Z, Xiang G, Minhu C, Liang D, Feng X, Min H, Pinjin H.

Ther Drug Monit. 2012 Dec;34(6):695-701. doi: 10.1097/FTD.0b013e3182731925.

PMID:
23149442
19.

Association between inosine triphosphate pyrophosphohydrolase deficiency and azathioprine-related adverse drug reactions in the Chinese kidney transplant recipients.

Xiong H, Xin HW, Wu XC, Li Q, Xiong L, Yu AR.

Fundam Clin Pharmacol. 2010 Jun;24(3):393-400. doi: 10.1111/j.1472-8206.2009.00770.x. Epub 2009 Aug 13.

PMID:
19682085
20.

Prospective evaluation of the pharmacogenetics of azathioprine in the treatment of inflammatory bowel disease.

Ansari A, Arenas M, Greenfield SM, Morris D, Lindsay J, Gilshenan K, Smith M, Lewis C, Marinaki A, Duley J, Sanderson J.

Aliment Pharmacol Ther. 2008 Oct 15;28(8):973-83. doi: 10.1111/j.1365-2036.2008.03788.x.

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