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Items: 1 to 20 of 125

1.

Making and breaking nucleic acids: two-Mg2+-ion catalysis and substrate specificity.

Yang W, Lee JY, Nowotny M.

Mol Cell. 2006 Apr 7;22(1):5-13. Review.

2.

Crystal structures of RNase H bound to an RNA/DNA hybrid: substrate specificity and metal-dependent catalysis.

Nowotny M, Gaidamakov SA, Crouch RJ, Yang W.

Cell. 2005 Jul 1;121(7):1005-16.

3.

Crystal structure of the catalytic core of an RNA-polymerase ribozyme.

Shechner DM, Grant RA, Bagby SC, Koldobskaya Y, Piccirilli JA, Bartel DP.

Science. 2009 Nov 27;326(5957):1271-5. doi: 10.1126/science.1174676.

4.

Hammerhead ribozymes: true metal or nucleobase catalysis? Where is the catalytic power from?

Leclerc F.

Molecules. 2010 Aug 6;15(8):5389-407. doi: 10.3390/molecules15085389.

5.

Getting a grip: polymerases and their substrate complexes.

Jäger J, Pata JD.

Curr Opin Struct Biol. 1999 Feb;9(1):21-8. Review.

PMID:
10047577
6.

Conservation of helical structure contributes to functional metal ion interactions in the catalytic domain of ribonuclease P RNA.

Kaye NM, Zahler NH, Christian EL, Harris ME.

J Mol Biol. 2002 Nov 29;324(3):429-42.

PMID:
12445779
7.

Structures of DNA and RNA polymerases and their interactions with nucleic acid substrates.

Arnold E, Ding J, Hughes SH, Hostomsky Z.

Curr Opin Struct Biol. 1995 Feb;5(1):27-38. Review.

PMID:
7539708
8.

Structural and catalytic roles for divalent magnesium in nucleic acid biochemistry.

Sreedhara A, Cowan JA.

Biometals. 2002 Sep;15(3):211-23. Review. No abstract available.

PMID:
12206388
9.

Iron mediates catalysis of nucleic acid processing enzymes: support for Fe(II) as a cofactor before the great oxidation event.

Okafor CD, Lanier KA, Petrov AS, Athavale SS, Bowman JC, Hud NV, Williams LD.

Nucleic Acids Res. 2017 Apr 20;45(7):3634-3642. doi: 10.1093/nar/gkx171.

10.

Magnesium is essential for formation of an active complex of a hammerhead ribozyme with its substrate: an investigation by NMR spectroscopy.

Orita M, Vinayak R, Andrus A, Takagi Y, Chiba A, Kaniwa H, Nishikawa F, Nishikawa S, Taira K.

Nucleic Acids Symp Ser. 1995;(34):219-20.

PMID:
8841630
11.

Creating RNA bulges: cleavage of RNA in RNA/DNA duplexes by metal ion catalysis.

Hüsken D, Goodall G, Blommers MJ, Jahnke W, Hall J, Häner R, Moser HE.

Biochemistry. 1996 Dec 24;35(51):16591-600.

PMID:
8987994
12.

Determination of catalytic parameters for hairpin ribozymes.

DeYoung MB, Siwkowski A, Hampel A.

Methods Mol Biol. 1997;74:209-20. No abstract available.

PMID:
9204436
13.

A core folding model for catalysis by the hammerhead ribozyme accounts for its extraordinary sensitivity to abasic mutations.

Peracchi A, Karpeisky A, Maloney L, Beigelman L, Herschlag D.

Biochemistry. 1998 Oct 20;37(42):14765-75.

PMID:
9778351
14.

Substitution of non-catalytic stem and loop regions of hammerhead ribozyme with DNA counterparts only increases KM without sacrificing the catalytic step (kcat): a way to improve substrate-specificity.

Shimayama T, Sawata S, Komiyama M, Takagi Y, Tanaka Y, Wada A, Sugimoto N, Rossi JJ, Nishikawa F, Nishikawa S, et al.

Nucleic Acids Symp Ser. 1992;(27):17-8.

PMID:
1283905
15.
17.

The C-terminal carboxy group of T7 RNA polymerase ensures efficient magnesium ion-dependent catalysis.

Lykke-Andersen J, Christiansen J.

Nucleic Acids Res. 1998 Dec 15;26(24):5630-5.

18.
20.

The involvement of the aspartate triad of the active center in all catalytic activities of multisubunit RNA polymerase.

Sosunov V, Zorov S, Sosunova E, Nikolaev A, Zakeyeva I, Bass I, Goldfarb A, Nikiforov V, Severinov K, Mustaev A.

Nucleic Acids Res. 2005 Jul 26;33(13):4202-11. Print 2005.

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