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Items: 1 to 20 of 60

1.

INSULIN-A PROBABLE GROSS MOLECULAR STRUCTURE.

Einstein JR, McGavin AS, Low BW.

Proc Natl Acad Sci U S A. 1963 Jan;49(1):74-81. No abstract available.

2.

INSULIN-GROSS MOLECULAR STRUCTURE: TRIAL-AND-ERROR STUDIES USING TRANSFORM AND PATTERSON FUNCTION TECHNIQUES.

McGavin AS, Einstein JR, Low BW.

Proc Natl Acad Sci U S A. 1962 Dec;48(12):2150-7. No abstract available.

3.

NMR structure of biosynthetic engineered human insulin monomer B31(Lys)-B32(Arg) in water/acetonitrile solution. Comparison with the solution structure of native human insulin monomer.

Bocian W, Borowicz P, Mikołajczyk J, Sitkowski J, Tarnowska A, Bednarek E, Głabski T, Tejchman-Małecka B, Bogiel M, Kozerski L.

Biopolymers. 2008 Oct;89(10):820-30. doi: 10.1002/bip.21018.

PMID:
18491415
4.

Structure of the insulin receptor ectodomain reveals a folded-over conformation.

McKern NM, Lawrence MC, Streltsov VA, Lou MZ, Adams TE, Lovrecz GO, Elleman TC, Richards KM, Bentley JD, Pilling PA, Hoyne PA, Cartledge KA, Pham TM, Lewis JL, Sankovich SE, Stoichevska V, Da Silva E, Robinson CP, Frenkel MJ, Sparrow LG, Fernley RT, Epa VC, Ward CW.

Nature. 2006 Sep 14;443(7108):218-21. Epub 2006 Sep 6.

PMID:
16957736
5.

Crystal structure of visfatin/pre-B cell colony-enhancing factor 1/nicotinamide phosphoribosyltransferase, free and in complex with the anti-cancer agent FK-866.

Kim MK, Lee JH, Kim H, Park SJ, Kim SH, Kang GB, Lee YS, Kim JB, Kim KK, Suh SW, Eom SH.

J Mol Biol. 2006 Sep 8;362(1):66-77. Epub 2006 Aug 9.

PMID:
16901503
6.

Structure and molecular dynamics simulation of archaeal prefoldin: the molecular mechanism for binding and recognition of nonnative substrate proteins.

Ohtaki A, Kida H, Miyata Y, Ide N, Yonezawa A, Arakawa T, Iizuka R, Noguchi K, Kita A, Odaka M, Miki K, Yohda M.

J Mol Biol. 2008 Feb 29;376(4):1130-41. doi: 10.1016/j.jmb.2007.12.010. Epub 2007 Dec 8.

PMID:
18201719
7.

Molecular mechanisms of differential intracellular signaling from the insulin receptor.

Jensen M, De Meyts P.

Vitam Horm. 2009;80:51-75. doi: 10.1016/S0083-6729(08)00603-1. Review.

PMID:
19251034
8.

A conserved histidine in insulin is required for the foldability of human proinsulin: structure and function of an ALAB5 analog.

Hua QX, Liu M, Hu SQ, Jia W, Arvan P, Weiss MA.

J Biol Chem. 2006 Aug 25;281(34):24889-99. Epub 2006 May 25.

9.

The N-terminal subdomain of insulin-like growth factor (IGF) binding protein 6. Structure and interaction with IGFs.

Chandrashekaran IR, Yao S, Wang CC, Bansal PS, Alewood PF, Forbes BE, Wallace JC, Bach LA, Norton RS.

Biochemistry. 2007 Mar 20;46(11):3065-74. Epub 2007 Feb 17.

PMID:
17305365
10.

Solution structure of ectodomains of the insulin receptor family: the ectodomain of the type 1 insulin-like growth factor receptor displays asymmetry of ligand binding accompanied by limited conformational change.

Whitten AE, Smith BJ, Menting JG, Margetts MB, McKern NM, Lovrecz GO, Adams TE, Richards K, Bentley JD, Trewhella J, Ward CW, Lawrence MC.

J Mol Biol. 2009 Dec 18;394(5):878-92. doi: 10.1016/j.jmb.2009.10.011. Epub 2009 Oct 14.

PMID:
19835884
11.

The sequence determinant causing different folding behaviors of insulin and insulin-like growth factor-1.

Huang QL, Zhao J, Tang YH, Shao SQ, Xu GJ, Feng YM.

Biochemistry. 2007 Jan 9;46(1):218-24.

PMID:
17198392
12.

The probable molecular association in liquid D-1-propanol through neutron diffraction.

Sahoo A, Sarkar S, Bhagat V, Joarder RN.

J Phys Chem A. 2009 Apr 30;113(17):5160-2. doi: 10.1021/jp8107717.

PMID:
19385682
13.

Crystal structure of ultralente--a microcrystalline insulin suspension.

Wagner A, Diez J, Schulze-Briese C, Schluckebier G.

Proteins. 2009 Mar;74(4):1018-27. doi: 10.1002/prot.22213.

PMID:
18767151
15.

Design, synthesis and pharmacological evaluation of cyclic mimetics of the insulin-like peptide 3 (INSL3) B-chain.

Shabanpoor F, Bathgate RA, Hossain MA, Giannakis E, Wade JD, Hughes RA.

J Pept Sci. 2007 Feb;13(2):113-20.

PMID:
17120268
16.

Structure of human insulin-like peptide 5 and characterization of conserved hydrogen bonds and electrostatic interactions within the relaxin framework.

Haugaard-Jönsson LM, Hossain MA, Daly NL, Craik DJ, Wade JD, Rosengren KJ.

Biochem J. 2009 May 1;419(3):619-27. doi: 10.1042/BJ20082353.

PMID:
19178384
17.

Transfection of insulin-secreting cell line and rat islets by functional polymeric gene vector.

Kang HC, Bae YH.

Biomaterials. 2009 May;30(14):2837-45. doi: 10.1016/j.biomaterials.2009.01.035. Epub 2009 Feb 5.

PMID:
19200594
18.

5-Substituted isophthalamides as insulin receptor sensitizers.

Robinson L, Bajjalieh S, Cairns N, Lum RT, Macsata RW, Manchem VP, Park SJ, Rao S, Schow SR, Shi S, Spevak WR.

Bioorg Med Chem Lett. 2008 Jun 15;18(12):3492-4. doi: 10.1016/j.bmcl.2008.05.031. Epub 2008 May 15.

PMID:
18513965
19.

Targeting insulin-like growth factor 1 receptor in sarcomas.

Scotlandi K, Picci P.

Curr Opin Oncol. 2008 Jul;20(4):419-27. doi: 10.1097/CCO.0b013e328302edab. Review.

PMID:
18525338
20.

Insulin receptor structure and its implications for the IGF-1 receptor.

Lawrence MC, McKern NM, Ward CW.

Curr Opin Struct Biol. 2007 Dec;17(6):699-705. Epub 2007 Sep 11. Review.

PMID:
17851071

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