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Items: 1 to 20 of 75

1.

The valosin-containing protein (VCP) is a target of Akt signaling required for cell survival.

Vandermoere F, El Yazidi-Belkoura I, Slomianny C, Demont Y, Bidaux G, Adriaenssens E, Lemoine J, Hondermarck H.

J Biol Chem. 2006 May 19;281(20):14307-13. Epub 2006 Mar 21.

2.

Proteomics exploration reveals that actin is a signaling target of the kinase Akt.

Vandermoere F, El Yazidi-Belkoura I, Demont Y, Slomianny C, Antol J, Lemoine J, Hondermarck H.

Mol Cell Proteomics. 2007 Jan;6(1):114-24. Epub 2006 Nov 4.

3.

Filamin A is a novel caveolin-1-dependent target in IGF-I-stimulated cancer cell migration.

Ravid D, Chuderland D, Landsman L, Lavie Y, Reich R, Liscovitch M.

Exp Cell Res. 2008 Sep 10;314(15):2762-73. doi: 10.1016/j.yexcr.2008.06.004. Epub 2008 Jun 12.

PMID:
18598695
4.

Rictor and integrin-linked kinase interact and regulate Akt phosphorylation and cancer cell survival.

McDonald PC, Oloumi A, Mills J, Dobreva I, Maidan M, Gray V, Wederell ED, Bally MB, Foster LJ, Dedhar S.

Cancer Res. 2008 Mar 15;68(6):1618-24. doi: 10.1158/0008-5472.CAN-07-5869.

5.

Epidermal growth factor receptor regulates osteoclast differentiation and survival through cross-talking with RANK signaling.

Yi T, Lee HL, Cha JH, Ko SI, Kim HJ, Shin HI, Woo KM, Ryoo HM, Kim GS, Baek JH.

J Cell Physiol. 2008 Nov;217(2):409-22. doi: 10.1002/jcp.21511.

PMID:
18543257
6.

Suberoylanilide hydroxamic acid induces Akt-mediated phosphorylation of p300, which promotes acetylation and transcriptional activation of RelA/p65.

Liu Y, Denlinger CE, Rundall BK, Smith PW, Jones DR.

J Biol Chem. 2006 Oct 20;281(42):31359-68. Epub 2006 Aug 21.

7.

Parathyroid hormone-related protein induces cell survival in human renal cell carcinoma through the PI3K Akt pathway: evidence for a critical role for integrin-linked kinase and nuclear factor kappa B.

Agouni A, Sourbier C, Danilin S, Rothhut S, Lindner V, Jacqmin D, Helwig JJ, Lang H, Massfelder T.

Carcinogenesis. 2007 Sep;28(9):1893-901. Epub 2007 Apr 29.

PMID:
17468516
8.

Inactivation of NF-kappaB by 3,3'-diindolylmethane contributes to increased apoptosis induced by chemotherapeutic agent in breast cancer cells.

Rahman KM, Ali S, Aboukameel A, Sarkar SH, Wang Z, Philip PA, Sakr WA, Raz A.

Mol Cancer Ther. 2007 Oct;6(10):2757-65. Epub 2007 Oct 3.

9.

p97/valosin-containing protein (VCP) is highly modulated by phosphorylation and acetylation.

Mori-Konya C, Kato N, Maeda R, Yasuda K, Higashimae N, Noguchi M, Koike M, Kimura Y, Ohizumi H, Hori S, Kakizuka A.

Genes Cells. 2009 Apr;14(4):483-97. doi: 10.1111/j.1365-2443.2009.01286.x.

10.

Hsp27 regulates Akt activation and polymorphonuclear leukocyte apoptosis by scaffolding MK2 to Akt signal complex.

Wu R, Kausar H, Johnson P, Montoya-Durango DE, Merchant M, Rane MJ.

J Biol Chem. 2007 Jul 27;282(30):21598-608. Epub 2007 May 17.

11.

Pre-B-cell leukemia transcription factor 1 regulates expression of valosin-containing protein, a gene involved in cancer growth.

Qiu Y, Tomita Y, Zhang B, Nakamichi I, Morii E, Aozasa K.

Am J Pathol. 2007 Jan;170(1):152-9.

13.

IGF-1 activates hEAG K(+) channels through an Akt-dependent signaling pathway in breast cancer cells: role in cell proliferation.

Borowiec AS, Hague F, Harir N, Guénin S, Guerineau F, Gouilleux F, Roudbaraki M, Lassoued K, Ouadid-Ahidouch H.

J Cell Physiol. 2007 Sep;212(3):690-701.

PMID:
17520698
14.

Sensitization of TNF-induced cytotoxicity in lung cancer cells by concurrent suppression of the NF-kappaB and Akt pathways.

Wang X, Chen W, Lin Y.

Biochem Biophys Res Commun. 2007 Apr 13;355(3):807-12. Epub 2007 Feb 12.

PMID:
17316570
15.

2-Anilino-4-aryl-1,3-thiazole inhibitors of valosin-containing protein (VCP or p97).

Bursavich MG, Parker DP, Willardsen JA, Gao ZH, Davis T, Ostanin K, Robinson R, Peterson A, Cimbora DM, Zhu JF, Richards B.

Bioorg Med Chem Lett. 2010 Mar 1;20(5):1677-9. doi: 10.1016/j.bmcl.2010.01.058. Epub 2010 Jan 21.

PMID:
20137940
16.

Distinctive role of integrin-mediated adhesion in TNF-induced PKB/Akt and NF-kappaB activation and endothelial cell survival.

Bieler G, Hasmim M, Monnier Y, Imaizumi N, Ameyar M, Bamat J, Ponsonnet L, Chouaib S, Grell M, Goodman SL, Lejeune F, Rüegg C.

Oncogene. 2007 Aug 23;26(39):5722-32. Epub 2007 Mar 19.

PMID:
17369858
17.

NF-kappaB activates transcription of the RNA-binding factor HuR, via PI3K-AKT signaling, to promote gastric tumorigenesis.

Kang MJ, Ryu BK, Lee MG, Han J, Lee JH, Ha TK, Byun DS, Chae KS, Lee BH, Chun HS, Lee KY, Kim HJ, Chi SG.

Gastroenterology. 2008 Dec;135(6):2030-42, 2042.e1-3. doi: 10.1053/j.gastro.2008.08.009. Epub 2008 Aug 20.

PMID:
18824170
19.

Genetic deletion of PKR abrogates TNF-induced activation of IkappaBalpha kinase, JNK, Akt and cell proliferation but potentiates p44/p42 MAPK and p38 MAPK activation.

Takada Y, Ichikawa H, Pataer A, Swisher S, Aggarwal BB.

Oncogene. 2007 Feb 22;26(8):1201-12. Epub 2006 Aug 21.

PMID:
16924232
20.

A role for Akt in the rapid regulation of inflammatory and apoptotic pathways in mouse bladder.

Tamarkin FJ, Kang WS, Cohen JJ, Wheeler MA, Weiss RM.

Naunyn Schmiedebergs Arch Pharmacol. 2006 Aug;373(5):349-59. Epub 2006 Jul 11.

PMID:
16832691

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