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Items: 1 to 20 of 337

1.

Crystal structure and site 1 binding energetics of human placental lactogen.

Walsh ST, Kossiakoff AA.

J Mol Biol. 2006 May 5;358(3):773-84. Epub 2006 Mar 2.

PMID:
16546209
2.

Mutational analysis and protein engineering of receptor-binding determinants in human placental lactogen.

Lowman HB, Cunningham BC, Wells JA.

J Biol Chem. 1991 Jun 15;266(17):10982-8.

4.

The X-ray structure of a growth hormone-prolactin receptor complex.

Somers W, Ultsch M, De Vos AM, Kossiakoff AA.

Nature. 1994 Dec 1;372(6505):478-81.

PMID:
7984244
6.

Shotgun alanine scanning shows that growth hormone can bind productively to its receptor through a drastically minimized interface.

Kouadio JL, Horn JR, Pal G, Kossiakoff AA.

J Biol Chem. 2005 Jul 8;280(27):25524-32. Epub 2005 Apr 26.

7.

Structural and functional analysis of the 1:1 growth hormone:receptor complex reveals the molecular basis for receptor affinity.

Clackson T, Ultsch MH, Wells JA, de Vos AM.

J Mol Biol. 1998 Apr 17;277(5):1111-28.

PMID:
9571026
9.

Ternary complex between placental lactogen and the extracellular domain of the prolactin receptor.

Elkins PA, Christinger HW, Sandowski Y, Sakal E, Gertler A, de Vos AM, Kossiakoff AA.

Nat Struct Biol. 2000 Sep;7(9):808-15.

PMID:
10966654
11.

The molecular basis for growth hormone-receptor interactions.

Wells JA, Cunningham BC, Fuh G, Lowman HB, Bass SH, Mulkerrin MG, Ultsch M, deVos AM.

Recent Prog Horm Res. 1993;48:253-75. Review.

PMID:
8441850
12.

The roles of placental growth hormone and placental lactogen in the regulation of human fetal growth and development.

Handwerger S, Freemark M.

J Pediatr Endocrinol Metab. 2000 Apr;13(4):343-56. Review.

PMID:
10776988
13.

High-resolution epitope mapping of hGH-receptor interactions by alanine-scanning mutagenesis.

Cunningham BC, Wells JA.

Science. 1989 Jun 2;244(4908):1081-5.

PMID:
2471267
14.

Affinity maturation of human growth hormone by monovalent phage display.

Lowman HB, Wells JA.

J Mol Biol. 1993 Dec 5;234(3):564-78.

PMID:
8254660
15.

Structural and mutational analysis of affinity-inert contact residues at the growth hormone-receptor interface.

Pearce KH Jr, Ultsch MH, Kelley RF, de Vos AM, Wells JA.

Biochemistry. 1996 Aug 13;35(32):10300-7.

PMID:
8756685
16.

Determination of the energetics governing the regulatory step in growth hormone-induced receptor homodimerization.

Bernat B, Pal G, Sun M, Kossiakoff AA.

Proc Natl Acad Sci U S A. 2003 Feb 4;100(3):952-7. Epub 2003 Jan 27.

17.

Computational detection of the binding-site hot spot at the remodeled human growth hormone-receptor interface.

Verkhivker GM, Bouzida D, Gehlhaar DK, Rejto PA, Freer ST, Rose PW.

Proteins. 2003 Nov 1;53(2):201-19.

PMID:
14517972
18.

Comparison of a structural and a functional epitope.

Cunningham BC, Wells JA.

J Mol Biol. 1993 Dec 5;234(3):554-63. Erratum in: J Mol Biol 1994 Apr 8;237(4):513.

PMID:
7504735
20.

Functional domains of human growth hormone necessary for the adipogenic activity of hGH/hPL chimeric molecules.

Juárez-Aguilar E, Castro-Muñozledo F, Guerra-Rodríguez NE, Reséndez-Pérez D, Martínez-Rodríguez HG, Barrera-Saldaña HA, Kuri-Harcuch W.

J Cell Sci. 1999 Sep;112 Pt 18:3127-35.

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