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Items: 1 to 20 of 42

1.

Novel arylpyrazole compounds selectively modulate glucocorticoid receptor regulatory activity.

Wang JC, Shah N, Pantoja C, Meijsing SH, Ho JD, Scanlan TS, Yamamoto KR.

Genes Dev. 2006 Mar 15;20(6):689-99.

2.

Differential in vivo effects on target pathways of a novel arylpyrazole glucocorticoid receptor modulator compared with prednisolone.

Roohk DJ, Varady KA, Turner SM, Emson CL, Gelling RW, Shankaran M, Lindwall G, Shipp LE, Scanlan TS, Wang JC, Hellerstein MK.

J Pharmacol Exp Ther. 2010 Apr;333(1):281-9. doi: 10.1124/jpet.109.162487. Epub 2010 Jan 11.

3.

Repression of TNF-alpha-induced IL-8 expression by the glucocorticoid receptor-beta involves inhibition of histone H4 acetylation.

Kim SH, Kim DH, Lavender P, Seo JH, Kim YS, Park JS, Kwak SJ, Jee YK.

Exp Mol Med. 2009 May 31;41(5):297-306. doi: 10.3858/emm.2009.41.5.033.

4.

Defective glucocorticoid receptor nuclear translocation and altered histone acetylation patterns in glucocorticoid-resistant patients.

Matthews JG, Ito K, Barnes PJ, Adcock IM.

J Allergy Clin Immunol. 2004 Jun;113(6):1100-8.

PMID:
15208591
6.

Chromatin immunoprecipitation scanning identifies glucocorticoid receptor binding regions in the proximal promoter of a ubiquitously expressed glucocorticoid target gene in brain.

van der Laan S, Sarabdjitsingh RA, Van Batenburg MF, Lachize SB, Li H, Dijkmans TF, Vreugdenhil E, de Kloet ER, Meijer OC.

J Neurochem. 2008 Sep;106(6):2515-23. doi: 10.1111/j.1471-4159.2008.05575.x. Epub 2008 Jul 15.

7.

Genomic analyses of transcription factor binding, histone acetylation, and gene expression reveal mechanistically distinct classes of estrogen-regulated promoters.

Kininis M, Chen BS, Diehl AG, Isaacs GD, Zhang T, Siepel AC, Clark AG, Kraus WL.

Mol Cell Biol. 2007 Jul;27(14):5090-104. Epub 2007 May 21.

9.

Autoregulation of human relaxin-2 gene expression critically involves relaxin and glucocorticoid receptor binding to glucocorticoid response half-sites in the relaxin-2 promoter.

Dschietzig T, Bartsch C, Wessler S, Baumann G, Stangl K.

Regul Pept. 2009 Jun 5;155(1-3):163-73. doi: 10.1016/j.regpep.2009.03.001. Epub 2009 Mar 14.

PMID:
19289144
10.

Developmental and hormonal regulation of progesterone receptor A-form expression in female mouse lung in vivo: interaction with glucocorticoid receptors.

Shao R, Egecioglu E, Weijdegård B, Ljungström K, Ling C, Fernandez-Rodriguez J, Billig H.

J Endocrinol. 2006 Sep;190(3):857-70.

11.

Ligand structural motifs can decouple glucocorticoid receptor transcriptional activation from target promoter occupancy.

Blind RD, Pineda-Torra I, Xu Y, Xu HE, Garabedian MJ.

Biochem Biophys Res Commun. 2012 Apr 20;420(4):839-44. doi: 10.1016/j.bbrc.2012.03.084. Epub 2012 Mar 23.

12.

Ligand-selective transactivation and transrepression via the glucocorticoid receptor: role of cofactor interaction.

Ronacher K, Hadley K, Avenant C, Stubsrud E, Simons SS Jr, Louw A, Hapgood JP.

Mol Cell Endocrinol. 2009 Feb 27;299(2):219-31. doi: 10.1016/j.mce.2008.10.008. Epub 2008 Oct 19.

PMID:
19007848
13.

Enhancement of ligand-dependent down-regulation of glucocorticoid receptor by lipopolysaccharide.

Hirasawa N, Yashima K, Ishihara K.

Life Sci. 2009 Oct 7;85(15-16):578-85. doi: 10.1016/j.lfs.2009.08.012. Epub 2009 Sep 2.

PMID:
19729027
14.

Ligand-based gene expression profiling reveals novel roles of glucocorticoid receptor in cardiac metabolism.

Yoshikawa N, Nagasaki M, Sano M, Tokudome S, Ueno K, Shimizu N, Imoto S, Miyano S, Suematsu M, Fukuda K, Morimoto C, Tanaka H.

Am J Physiol Endocrinol Metab. 2009 Jun;296(6):E1363-73. doi: 10.1152/ajpendo.90767.2008. Epub 2009 Mar 17.

15.

Glucocorticoid-induced alternative promoter usage for a novel 5' variant of granzyme A.

Ruike Y, Katsuma S, Hirasawa A, Tsujimoto G.

J Hum Genet. 2007;52(2):172-8. Epub 2006 Dec 19.

PMID:
17180578
16.

Molecular mechanisms for corticotropin-releasing hormone gene repression by glucocorticoid in BE(2)C neuronal cell line.

Yamamori E, Iwasaki Y, Taguchi T, Nishiyama M, Yoshida M, Asai M, Oiso Y, Itoi K, Kambayashi M, Hashimoto K.

Mol Cell Endocrinol. 2007 Jan 29;264(1-2):142-8. Epub 2006 Dec 13.

PMID:
17169483
17.

Histone acetylation characterizes chromatin presetting by NF1 and Oct1 and enhances glucocorticoid receptor binding to the MMTV promoter.

Astrand C, Belikov S, Wrange O.

Exp Cell Res. 2009 Sep 10;315(15):2604-15. doi: 10.1016/j.yexcr.2009.05.012. Epub 2009 May 20.

PMID:
19463811
18.

Reduction of glucocorticoid receptor ligand binding by the 11-beta hydroxysteroid dehydrogenase type 2 inhibitor, Thiram.

Garbrecht MR, Krozowski ZS, Snyder JM, Schmidt TJ.

Steroids. 2006 Oct;71(10):895-901. Epub 2006 Jul 18.

PMID:
16857225
19.

Glucocorticoids and tumor necrosis factor-alpha synergize to induce absorption by the epithelial sodium channel in the colon.

Bergann T, Zeissig S, Fromm A, Richter JF, Fromm M, Schulzke JD.

Gastroenterology. 2009 Mar;136(3):933-42. doi: 10.1053/j.gastro.2008.12.008. Epub 2008 Dec 10.

PMID:
19185581
20.

Selective glucocorticoid receptor ligands.

Cole TJ, Mollard R.

Med Chem. 2007 Sep;3(5):494-506.

PMID:
17897077

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