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Items: 1 to 20 of 95

1.

Virtual and biomolecular screening converge on a selective agonist for GPR30.

Bologa CG, Revankar CM, Young SM, Edwards BS, Arterburn JB, Kiselyov AS, Parker MA, Tkachenko SE, Savchuck NP, Sklar LA, Oprea TI, Prossnitz ER.

Nat Chem Biol. 2006 Apr;2(4):207-12. Epub 2006 Mar 5.

PMID:
16520733
2.

Synthetic estrogen derivatives demonstrate the functionality of intracellular GPR30.

Revankar CM, Mitchell HD, Field AS, Burai R, Corona C, Ramesh C, Sklar LA, Arterburn JB, Prossnitz ER.

ACS Chem Biol. 2007 Aug 17;2(8):536-44. Epub 2007 Jul 27.

PMID:
17655271
3.

A transmembrane intracellular estrogen receptor mediates rapid cell signaling.

Revankar CM, Cimino DF, Sklar LA, Arterburn JB, Prossnitz ER.

Science. 2005 Mar 11;307(5715):1625-30. Epub 2005 Feb 10.

4.

GPR30: a novel therapeutic target in estrogen-related disease.

Prossnitz ER, Sklar LA, Oprea TI, Arterburn JB.

Trends Pharmacol Sci. 2008 Mar;29(3):116-23. doi: 10.1016/j.tips.2008.01.001. Epub 2008 Feb 11.

PMID:
18262661
5.

G protein-coupled receptor 30 (GPR30) mediates gene expression changes and growth response to 17beta-estradiol and selective GPR30 ligand G-1 in ovarian cancer cells.

Albanito L, Madeo A, Lappano R, Vivacqua A, Rago V, Carpino A, Oprea TI, Prossnitz ER, Musti AM, Andò S, Maggiolini M.

Cancer Res. 2007 Feb 15;67(4):1859-66.

6.

A new membrane G protein-coupled receptor (GPR30) is involved in the cardiac effects of 17beta-estradiol in the male rat.

Filice E, Recchia AG, Pellegrino D, Angelone T, Maggiolini M, Cerra MC.

J Physiol Pharmacol. 2009 Dec;60(4):3-10.

7.

GPR30: a seven-transmembrane-spanning estrogen receptor that triggers EGF release.

Filardo EJ, Thomas P.

Trends Endocrinol Metab. 2005 Oct;16(8):362-7. Review.

PMID:
16125968
8.

Identification of ligands with bicyclic scaffolds provides insights into mechanisms of estrogen receptor subtype selectivity.

Hsieh RW, Rajan SS, Sharma SK, Guo Y, DeSombre ER, Mrksich M, Greene GL.

J Biol Chem. 2006 Jun 30;281(26):17909-19. Epub 2006 Apr 28.

10.

What does an orphan G-protein-coupled receptor have to do with estrogen?

Rae JM, Johnson MD.

Breast Cancer Res. 2005;7(6):243-4. Epub 2005 Sep 29.

11.

Evaluation of ligand selectivity using reporter cell lines stably expressing estrogen receptor alpha or beta.

Escande A, Pillon A, Servant N, Cravedi JP, Larrea F, Muhn P, Nicolas JC, Cavaillès V, Balaguer P.

Biochem Pharmacol. 2006 May 14;71(10):1459-69. Epub 2006 Mar 22.

PMID:
16554039
12.

A critical review of fundamental controversies in the field of GPR30 research.

Langer G, Bader B, Meoli L, Isensee J, Delbeck M, Noppinger PR, Otto C.

Steroids. 2010 Aug-Sep;75(8-9):603-10. doi: 10.1016/j.steroids.2009.12.006. Epub 2009 Dec 23. Review.

PMID:
20034504
13.

G protein-coupled receptor 30 localizes to the endoplasmic reticulum and is not activated by estradiol.

Otto C, Rohde-Schulz B, Schwarz G, Fuchs I, Klewer M, Brittain D, Langer G, Bader B, Prelle K, Nubbemeyer R, Fritzemeier KH.

Endocrinology. 2008 Oct;149(10):4846-56. doi: 10.1210/en.2008-0269. Epub 2008 Jun 19.

PMID:
18566127
14.

The unfolding stories of GPR30, a new membrane-bound estrogen receptor.

Maggiolini M, Picard D.

J Endocrinol. 2010 Feb;204(2):105-14. doi: 10.1677/JOE-09-0242. Epub 2009 Sep 18. Review.

15.

In vivo effects of a GPR30 antagonist.

Dennis MK, Burai R, Ramesh C, Petrie WK, Alcon SN, Nayak TK, Bologa CG, Leitao A, Brailoiu E, Deliu E, Dun NJ, Sklar LA, Hathaway HJ, Arterburn JB, Oprea TI, Prossnitz ER.

Nat Chem Biol. 2009 Jun;5(6):421-7. doi: 10.1038/nchembio.168.

16.

G protein-coupled receptor 30 is an estrogen receptor in the plasma membrane.

Funakoshi T, Yanai A, Shinoda K, Kawano MM, Mizukami Y.

Biochem Biophys Res Commun. 2006 Aug 4;346(3):904-10. Epub 2006 Jun 9.

PMID:
16780796
17.

Estrogen receptor beta: an overview and update.

Zhao C, Dahlman-Wright K, Gustafsson JA.

Nucl Recept Signal. 2008 Feb 1;6:e003. doi: 10.1621/nrs.06003. Review.

18.

Association of the membrane estrogen receptor, GPR30, with breast tumor metastasis and transactivation of the epidermal growth factor receptor.

Filardo EJ, Quinn JA, Sabo E.

Steroids. 2008 Oct;73(9-10):870-3. doi: 10.1016/j.steroids.2007.12.025. Epub 2008 Jan 3. Review.

PMID:
18289622
19.

Computational insights into the mechanism of ligand unbinding and selectivity of estrogen receptors.

Shen J, Li W, Liu G, Tang Y, Jiang H.

J Phys Chem B. 2009 Jul 30;113(30):10436-44. doi: 10.1021/jp903785h.

PMID:
19583238
20.

Synthesis and binding affinity to human alpha and beta estrogen receptors of various 7-hydroxycoumarins substituted at 4- and 3,4- positions.

Kirkiacharian S, Lormier AT, Chidiack H, Bouchoux F, Cérède E.

Farmaco. 2004 Dec;59(12):981-6.

PMID:
15598433

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