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Items: 1 to 20 of 101

1.

Protein kinase WNK3 increases cell survival in a caspase-3-dependent pathway.

Veríssimo F, Silva E, Morris JD, Pepperkok R, Jordan P.

Oncogene. 2006 Jul 13;25(30):4172-82. Epub 2006 Feb 27.

PMID:
16501604
2.

Protein kinase WNK2 inhibits cell proliferation by negatively modulating the activation of MEK1/ERK1/2.

Moniz S, Veríssimo F, Matos P, Brazão R, Silva E, Kotelevets L, Chastre E, Gespach C, Jordan P.

Oncogene. 2007 Sep 6;26(41):6071-81. Epub 2007 Jul 30. Erratum in: Oncogene. 2008 Jan 3;27(1):155. Kotevelets, L [corrected to Kotelevets, L].

PMID:
17667937
3.

Tpl-2 induces apoptosis by promoting the assembly of protein complexes that contain caspase-9, the adapter protein Tvl-1, and procaspase-3.

Patriotis C, Russeva MG, Lin JH, Srinivasula SM, Markova DZ, Tsatsanis C, Makris A, Alnemri ES, Tsichlis PN.

J Cell Physiol. 2001 May;187(2):176-87.

PMID:
11267997
4.

WNK kinases: molecular regulators of integrated epithelial ion transport.

Kahle KT, Wilson FH, Lalioti M, Toka H, Qin H, Lifton RP.

Curr Opin Nephrol Hypertens. 2004 Sep;13(5):557-62. Review.

PMID:
15300163
5.

Mahanine inhibits growth and induces apoptosis in prostate cancer cells through the deactivation of Akt and activation of caspases.

Sinha S, Pal BC, Jagadeesh S, Banerjee PP, Bandyopadhaya A, Bhattacharya S.

Prostate. 2006 Sep 1;66(12):1257-65.

PMID:
16683271
6.

Intersectin links WNK kinases to endocytosis of ROMK1.

He G, Wang HR, Huang SK, Huang CL.

J Clin Invest. 2007 Apr;117(4):1078-87. Epub 2007 Mar 22.

7.

Properties of WNK1 and implications for other family members.

Lenertz LY, Lee BH, Min X, Xu BE, Wedin K, Earnest S, Goldsmith EJ, Cobb MH.

J Biol Chem. 2005 Jul 22;280(29):26653-8. Epub 2005 May 9.

8.

WNK kinases and essential hypertension.

Huang CL, Kuo E, Toto RD.

Curr Opin Nephrol Hypertens. 2008 Mar;17(2):133-7. doi: 10.1097/MNH.0b013e3282f4e4fd. Review.

PMID:
18277144
9.

Indomethacin induces apoptosis in 786-O renal cell carcinoma cells by activating mitogen-activated protein kinases and AKT.

Ou YC, Yang CR, Cheng CL, Raung SL, Hung YY, Chen CJ.

Eur J Pharmacol. 2007 Jun 1;563(1-3):49-60. Epub 2007 Feb 8.

PMID:
17341418
10.

Initiation of caspase-independent death in mouse mesangial cells by Cd2+: involvement of p38 kinase and CaMK-II.

Liu Y, Templeton DM.

J Cell Physiol. 2008 Nov;217(2):307-18. doi: 10.1002/jcp.21499.

PMID:
18506790
11.

SOK1 translocates from the Golgi to the nucleus upon chemical anoxia and induces apoptotic cell death.

Nogueira E, Fidalgo M, Molnar A, Kyriakis J, Force T, Zalvide J, Pombo CM.

J Biol Chem. 2008 Jun 6;283(23):16248-58. doi: 10.1074/jbc.M709724200. Epub 2008 Mar 25.

12.

Emerging roles for WNK kinases in cancer.

Moniz S, Jordan P.

Cell Mol Life Sci. 2010 Apr;67(8):1265-76. doi: 10.1007/s00018-010-0261-6. Epub 2010 Jan 22. Review.

PMID:
20094755
13.

Therapeutic hypothermia modulates TNFR1 signaling in the traumatized brain via early transient activation of the JNK pathway and suppression of XIAP cleavage.

Lotocki G, de Rivero Vaccari JP, Perez ER, Alonso OF, Curbelo K, Keane RW, Dietrich WD.

Eur J Neurosci. 2006 Oct;24(8):2283-90.

PMID:
17074049
14.

Human hypertension caused by mutations in WNK kinases.

Wilson FH, Disse-Nicodème S, Choate KA, Ishikawa K, Nelson-Williams C, Desitter I, Gunel M, Milford DV, Lipkin GW, Achard JM, Feely MP, Dussol B, Berland Y, Unwin RJ, Mayan H, Simon DB, Farfel Z, Jeunemaitre X, Lifton RP.

Science. 2001 Aug 10;293(5532):1107-12.

15.

WNK1: analysis of protein kinase structure, downstream targets, and potential roles in hypertension.

Xu BE, Lee BH, Min X, Lenertz L, Heise CJ, Stippec S, Goldsmith EJ, Cobb MH.

Cell Res. 2005 Jan;15(1):6-10. Review.

16.

Role of with-no-lysine [K] kinases in the pathogenesis of Gordon's syndrome.

Xie J, Craig L, Cobb MH, Huang CL.

Pediatr Nephrol. 2006 Sep;21(9):1231-6. Epub 2006 May 9. Review.

PMID:
16683163
17.

WNK kinases, a novel protein kinase subfamily in multi-cellular organisms.

Veríssimo F, Jordan P.

Oncogene. 2001 Sep 6;20(39):5562-9.

18.
19.

OSU-03012 promotes caspase-independent but PERK-, cathepsin B-, BID-, and AIF-dependent killing of transformed cells.

Yacoub A, Park MA, Hanna D, Hong Y, Mitchell C, Pandya AP, Harada H, Powis G, Chen CS, Koumenis C, Grant S, Dent P.

Mol Pharmacol. 2006 Aug;70(2):589-603. Epub 2006 Apr 18.

20.

Caspase-2 is activated at the CD95 death-inducing signaling complex in the course of CD95-induced apoptosis.

Lavrik IN, Golks A, Baumann S, Krammer PH.

Blood. 2006 Jul 15;108(2):559-65.

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