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Items: 1 to 20 of 194

1.

Modelling thymic HIV-1 Nef effects.

Stove V, Verhasselt B.

Curr HIV Res. 2006 Jan;4(1):57-64. Review.

PMID:
16454711
2.

HIV-1 Nef mutations abrogating downregulation of CD4 affect other Nef functions and show reduced pathogenicity in transgenic mice.

Hanna Z, Priceputu E, Hu C, Vincent P, Jolicoeur P.

Virology. 2006 Mar 1;346(1):40-52. Epub 2005 Nov 28.

3.
4.

Enhanced CD4 down-modulation by late stage HIV-1 nef alleles is associated with increased Env incorporation and viral replication.

Argañaraz ER, Schindler M, Kirchhoff F, Cortes MJ, Lama J.

J Biol Chem. 2003 Sep 5;278(36):33912-9. Epub 2003 Jun 19.

5.

In vivo analysis of Nef function.

Wei BL, Arora VK, Foster JL, Sodora DL, Garcia JV.

Curr HIV Res. 2003 Jan;1(1):41-50. Review.

PMID:
15043211
6.

Requirement of nef for HIV-1 infectivity is biased by the expression levels of Env in the virus-producing cells and CD4 in the target cells.

Tobiume M, Tokunaga K, Kiyokawa E, Takahoko M, Mochizuki N, Tatsumi M, Matsuda M.

Arch Virol. 2001;146(9):1739-51.

PMID:
11699959
7.

HIV- I Nef severely impairs thymocyte development and peripheral T-cell function by a CD4-independent mechanism.

Pennington DJ, Jenkins SA, Brady HJ, Miles CG, Dzierzak EA, Abraham DJ.

Genes Funct. 1997 Dec;1(5-6):321-35.

PMID:
17366702
9.

Functional characterization of HIV-1 Nef mutants in the context of viral infection.

Fackler OT, Moris A, Tibroni N, Giese SI, Glass B, Schwartz O, Kräusslich HG.

Virology. 2006 Aug 1;351(2):322-39. Epub 2006 May 8.

10.

Primary human immunodeficiency virus type 1 nef alleles show major differences in pathogenicity in transgenic mice.

Priceputu E, Hanna Z, Hu C, Simard MC, Vincent P, Wildum S, Schindler M, Kirchhoff F, Jolicoeur P.

J Virol. 2007 May;81(9):4677-93. Epub 2007 Feb 21.

12.

Endocytosis of major histocompatibility complex class I molecules is induced by the HIV-1 Nef protein.

Schwartz O, Maréchal V, Le Gall S, Lemonnier F, Heard JM.

Nat Med. 1996 Mar;2(3):338-42.

PMID:
8612235
13.

Biological roles of HIV Nef proteins. A minireview.

Cernescu C, Ruţă S.

Rev Roum Virol. 1992 Jan-Jun;43(1-2):95-100. Review.

PMID:
1288645
14.

Modulation of different human immunodeficiency virus type 1 Nef functions during progression to AIDS.

Carl S, Greenough TC, Krumbiegel M, Greenberg M, Skowronski J, Sullivan JL, Kirchhoff F.

J Virol. 2001 Apr;75(8):3657-65.

15.

Modulation of specific surface receptors and activation sensitization in primary resting CD4+ T lymphocytes by the Nef protein of HIV-1.

Keppler OT, Tibroni N, Venzke S, Rauch S, Fackler OT.

J Leukoc Biol. 2006 Mar;79(3):616-27. Epub 2005 Dec 19.

PMID:
16365153
16.
18.

Human immunodeficiency virus nef gene expression affects generation and function of human T cells, but not dendritic cells.

Verhasselt B, Naessens E, Verhofstede C, De Smedt M, Schollen S, Kerre T, Vanhecke D, Plum J.

Blood. 1999 Oct 15;94(8):2809-18.

19.

Activation of p21-activated kinase 2 and its association with Nef are conserved in murine cells but are not sufficient to induce an AIDS-like disease in CD4C/HIV transgenic mice.

Vincent P, Priceputu E, Kay D, Saksela K, Jolicoeur P, Hanna Z.

J Biol Chem. 2006 Mar 17;281(11):6940-54. Epub 2005 Dec 28.

20.

The effects of HIV-1 Nef on CD4 surface expression and viral infectivity in lymphoid cells are independent of rafts.

Sol-Foulon N, Esnault C, Percherancier Y, Porrot F, Metais-Cunha P, Bachelerie F, Schwartz O.

J Biol Chem. 2004 Jul 23;279(30):31398-408. Epub 2004 May 7.

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