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Items: 1 to 20 of 61

1.

Protein kinase Calpha and epsilon small-molecule targeted therapeutics: a new roadmap to two Holy Grails in drug discovery?

O'Brian CA, Chu F, Bornmann WG, Maxwell DS.

Expert Rev Anticancer Ther. 2006 Feb;6(2):175-86. Review.

PMID:
16445370
3.

Differential roles of PKCalpha and PKCepsilon in controlling the gene expression of Nox4 in human endothelial cells.

Xu H, Goettsch C, Xia N, Horke S, Morawietz H, Förstermann U, Li H.

Free Radic Biol Med. 2008 Apr 15;44(8):1656-67. doi: 10.1016/j.freeradbiomed.2008.01.023. Epub 2008 Feb 7.

PMID:
18291120
4.
5.

Angiotensin II activates p44/42 MAP kinase partly through PKCepsilon in H295R cells.

Lehoux JG, Lefebvre A.

Mol Cell Endocrinol. 2007 Feb;265-266:121-5. Epub 2007 Jan 9.

PMID:
17215072
6.

[The role of CPI-17 in vascular calcium sensitivity regulated by protein kinase Calpha and Cepsilon in rats with hemorrhagic shock].

Xu J, Yang GM, Li T, Ming J, Chen W, Liu LM.

Zhonghua Shao Shang Za Zhi. 2009 Jun;25(3):167-70. Chinese.

PMID:
19842549
7.

Selective Modulation of Protein Kinase C α over Protein Kinase C ε by Curcumin and Its Derivatives in CHO-K1 Cells.

Pany S, Majhi A, Das J.

Biochemistry. 2016 Apr 12;55(14):2135-43. doi: 10.1021/acs.biochem.6b00057. Epub 2016 Mar 25.

PMID:
26983836
8.

Protein kinase Calpha is involved in interferon regulatory factor 3 activation and type I interferon-beta synthesis.

Johnson J, Albarani V, Nguyen M, Goldman M, Willems F, Aksoy E.

J Biol Chem. 2007 May 18;282(20):15022-32. Epub 2007 Feb 12.

9.

The regulation of glycine transporter GLYT1 is mainly mediated by protein kinase Calpha in C6 glioma cells.

Morioka N, Abdin JM, Morita K, Kitayama T, Nakata Y, Dohi T.

Neurochem Int. 2008 Dec;53(6-8):248-54. doi: 10.1016/j.neuint.2008.08.002. Epub 2008 Aug 19.

PMID:
18778746
10.

The linoleic acid derivative DCP-LA selectively activates PKC-epsilon, possibly binding to the phosphatidylserine binding site.

Kanno T, Yamamoto H, Yaguchi T, Hi R, Mukasa T, Fujikawa H, Nagata T, Yamamoto S, Tanaka A, Nishizaki T.

J Lipid Res. 2006 Jun;47(6):1146-56. Epub 2006 Mar 6.

11.

Overexpression of PKCalpha is required to impart estradiol inhibition and tamoxifen-resistance in a T47D human breast cancer tumor model.

Lin X, Yu Y, Zhao H, Zhang Y, Manela J, Tonetti DA.

Carcinogenesis. 2006 Aug;27(8):1538-46. Epub 2006 Mar 2.

PMID:
16513679
12.

Feedlot dust stimulation of interleukin-6 and -8 requires protein kinase Cepsilon in human bronchial epithelial cells.

Wyatt TA, Slager RE, Devasure J, Auvermann BW, Mulhern ML, Von Essen S, Mathisen T, Floreani AA, Romberger DJ.

Am J Physiol Lung Cell Mol Physiol. 2007 Nov;293(5):L1163-70. Epub 2007 Aug 24.

13.

Protein kinase Cepsilon and development of squamous cell carcinoma, the nonmelanoma human skin cancer.

Verma AK, Wheeler DL, Aziz MH, Manoharan H.

Mol Carcinog. 2006 Jun;45(6):381-8. Review.

PMID:
16683253
14.

The last 10 amino acid residues beyond the hydrophobic motif are critical for the catalytic competence and function of protein kinase Calpha.

Yeong SS, Zhu Y, Smith D, Verma C, Lim WG, Tan BJ, Li QT, Cheung NS, Cai M, Zhu YZ, Zhou SF, Tan SL, Duan W.

J Biol Chem. 2006 Oct 13;281(41):30768-81. Epub 2006 Aug 8.

15.

Protein-protein interactions as targets for small-molecule therapeutics in cancer.

White AW, Westwell AD, Brahemi G.

Expert Rev Mol Med. 2008 Mar 19;10:e8. doi: 10.1017/S1462399408000641. Review.

PMID:
18353193
16.

Protein kinase Calpha and sphingosine 1-phosphate-dependent signaling in endothelial cell.

Thompson B, Ancellin N, Fernandez SM, Hla T, Sha'afi RI.

Prostaglandins Other Lipid Mediat. 2006 Jul;80(1-2):15-27. Epub 2006 Jul 7.

PMID:
16846783
17.

PKCepsilon is essential for gelsolin expression by histone deacetylase inhibitor apicidin in human cervix cancer cells.

Eun DW, Ahn SH, You JS, Park JW, Lee EK, Lee HN, Kang GM, Lee JC, Choi WS, Seo DW, Han JW.

Biochem Biophys Res Commun. 2007 Mar 16;354(3):769-75. Epub 2007 Jan 17.

PMID:
17257588
18.
19.

Protein kinase Cepsilon is important for migration of neuroblastoma cells.

Stensman H, Larsson C.

BMC Cancer. 2008 Dec 11;8:365. doi: 10.1186/1471-2407-8-365.

20.

A spatiotemporally coordinated cascade of protein kinase C activation controls isoform-selective translocation.

Collazos A, Diouf B, Guérineau NC, Quittau-Prévostel C, Peter M, Coudane F, Hollande F, Joubert D.

Mol Cell Biol. 2006 Mar;26(6):2247-61.

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