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Items: 1 to 20 of 132


The HIV-1 Vpr and glucocorticoid receptor complex is a gain-of-function interaction that prevents the nuclear localization of PARP-1.

Muthumani K, Choo AY, Zong WX, Madesh M, Hwang DS, Premkumar A, Thieu KP, Emmanuel J, Kumar S, Thompson CB, Weiner DB.

Nat Cell Biol. 2006 Feb;8(2):170-9. Epub 2006 Jan 22. Erratum in: Nat Cell Biol. 2006 Mar;8(3):299.


Poly(ADP-ribose) polymerase-1 is a determining factor in Crm1-mediated nuclear export and retention of p65 NF-kappa B upon TLR4 stimulation.

Zerfaoui M, Errami Y, Naura AS, Suzuki Y, Kim H, Ju J, Liu T, Hans CP, Kim JG, Abd Elmageed ZY, Koochekpour S, Catling A, Boulares AH.

J Immunol. 2010 Aug 1;185(3):1894-902. doi: 10.4049/jimmunol.1000646. Epub 2010 Jul 7.


The glucocorticoid receptor type II complex is a target of the HIV-1 vpr gene product.

Refaeli Y, Levy DN, Weiner DB.

Proc Natl Acad Sci U S A. 1995 Apr 11;92(8):3621-5.


Characterization of mechanisms involved in transrepression of NF-kappa B by activated glucocorticoid receptors.

Scheinman RI, Gualberto A, Jewell CM, Cidlowski JA, Baldwin AS Jr.

Mol Cell Biol. 1995 Feb;15(2):943-53.


Structure-functional analysis of human immunodeficiency virus type 1 (HIV-1) Vpr: role of leucine residues on Vpr-mediated transactivation and virus replication.

Thotala D, Schafer EA, Tungaturthi PK, Majumder B, Janket ML, Wagner M, Srinivasan A, Watkins S, Ayyavoo V.

Virology. 2004 Oct 10;328(1):89-100. Erratum in: Virology. 2005 Feb 20;332(2):691.


Critical role of the automodification of poly(ADP-ribose) polymerase-1 in nuclear factor-kappaB-dependent gene expression in primary cultured mouse glial cells.

Nakajima H, Nagaso H, Kakui N, Ishikawa M, Hiranuma T, Hoshiko S.

J Biol Chem. 2004 Oct 8;279(41):42774-86. Epub 2004 Aug 9.


Carboxyl terminus of hVIP/mov34 is critical for HIV-1-Vpr interaction and glucocorticoid-mediated signaling.

Ramanathan MP, Curley E 3rd, Su M, Chambers JA, Weiner DB.

J Biol Chem. 2002 Dec 6;277(49):47854-60. Epub 2002 Sep 16.


NF-kappaB signalling is inhibited by glucocorticoid receptor and STAT6 via distinct mechanisms.

Nelson G, Wilde GJ, Spiller DG, Kennedy SM, Ray DW, Sullivan E, Unitt JF, White MR.

J Cell Sci. 2003 Jun 15;116(Pt 12):2495-503. Epub 2003 May 6.


Resistance to endotoxic shock as a consequence of defective NF-kappaB activation in poly (ADP-ribose) polymerase-1 deficient mice.

Oliver FJ, Ménissier-de Murcia J, Nacci C, Decker P, Andriantsitohaina R, Muller S, de la Rubia G, Stoclet JC, de Murcia G.

EMBO J. 1999 Aug 16;18(16):4446-54.


The progestin-only contraceptive medroxyprogesterone acetate, but not norethisterone acetate, enhances HIV-1 Vpr-mediated apoptosis in human CD4+ T cells through the glucocorticoid receptor.

Tomasicchio M, Avenant C, Du Toit A, Ray RM, Hapgood JP.

PLoS One. 2013 May 3;8(5):e62895. doi: 10.1371/journal.pone.0062895. Print 2013.


Acetylation of poly(ADP-ribose) polymerase-1 by p300/CREB-binding protein regulates coactivation of NF-kappaB-dependent transcription.

Hassa PO, Haenni SS, Buerki C, Meier NI, Lane WS, Owen H, Gersbach M, Imhof R, Hottiger MO.

J Biol Chem. 2005 Dec 9;280(49):40450-64. Epub 2005 Oct 4.


Lipopolysaccharide activates ERK-PARP-1-RelA pathway and promotes nuclear factor-κB transcription in murine macrophages.

Liu L, Ke Y, Jiang X, He F, Pan L, Xu L, Zeng X, Ba X.

Hum Immunol. 2012 May;73(5):439-47. doi: 10.1016/j.humimm.2012.02.002. Epub 2012 Feb 21.


Transcriptional coactivation of nuclear factor-kappaB-dependent gene expression by p300 is regulated by poly(ADP)-ribose polymerase-1.

Hassa PO, Buerki C, Lombardi C, Imhof R, Hottiger MO.

J Biol Chem. 2003 Nov 14;278(46):45145-53. Epub 2003 Sep 5.


Synthetic Vpr protein activates activator protein-1, c-Jun N-terminal kinase, and NF-kappaB and stimulates HIV-1 transcription in promonocytic cells and primary macrophages.

Varin A, Decrion AZ, Sabbah E, Quivy V, Sire J, Van Lint C, Roques BP, Aggarwal BB, Herbein G.

J Biol Chem. 2005 Dec 30;280(52):42557-67. Epub 2005 Oct 21.

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