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FDG-PET imaging of pulmonary inflammation in healthy volunteers after airway instillation of endotoxin.

Chen DL, Rosenbluth DB, Mintun MA, Schuster DP.

J Appl Physiol (1985). 2006 May;100(5):1602-9. Epub 2006 Jan 19.


Positron emission tomography with [18F]fluorodeoxyglucose to evaluate neutrophil kinetics during acute lung injury.

Chen DL, Schuster DP.

Am J Physiol Lung Cell Mol Physiol. 2004 Apr;286(4):L834-40. Epub 2003 Dec 5.


[18F]fluorodeoxyglucose positron emission tomography for lung antiinflammatory response evaluation.

Chen DL, Bedient TJ, Kozlowski J, Rosenbluth DB, Isakow W, Ferkol TW, Thomas B, Mintun MA, Schuster DP, Walter MJ.

Am J Respir Crit Care Med. 2009 Sep 15;180(6):533-9. doi: 10.1164/rccm.200904-0501OC. Epub 2009 Jul 2.


Imaging pulmonary inducible nitric oxide synthase expression with PET.

Huang HJ, Isakow W, Byers DE, Engle JT, Griffin EA, Kemp D, Brody SL, Gropler RJ, Miller JP, Chu W, Zhou D, Pierce RA, Castro M, Mach RH, Chen DL.

J Nucl Med. 2015 Jan;56(1):76-81. doi: 10.2967/jnumed.114.146381. Epub 2014 Dec 18.


Quantifying pulmonary inflammation in cystic fibrosis with positron emission tomography.

Chen DL, Ferkol TW, Mintun MA, Pittman JE, Rosenbluth DB, Schuster DP.

Am J Respir Crit Care Med. 2006 Jun 15;173(12):1363-9. Epub 2006 Mar 16.


Mild endotoxemia during mechanical ventilation produces spatially heterogeneous pulmonary neutrophilic inflammation in sheep.

Costa EL, Musch G, Winkler T, Schroeder T, Harris RS, Jones HA, Venegas JG, Vidal Melo MF.

Anesthesiology. 2010 Mar;112(3):658-69. doi: 10.1097/ALN.0b013e3181cbd1d4.


Local inflammatory responses following bronchial endotoxin instillation in humans.

O'Grady NP, Preas HL, Pugin J, Fiuza C, Tropea M, Reda D, Banks SM, Suffredini AF.

Am J Respir Crit Care Med. 2001 Jun;163(7):1591-8.


Imaging pulmonary inflammation with positron emission tomography: a biomarker for drug development.

Chen DL, Schuster DP.

Mol Pharm. 2006 Sep-Oct;3(5):488-95. Review.


Glucose transporter-1 distribution in fibrotic lung disease: association with [¹⁸F]-2-fluoro-2-deoxyglucose-PET scan uptake, inflammation, and neovascularization.

El-Chemaly S, Malide D, Yao J, Nathan SD, Rosas IO, Gahl WA, Moss J, Gochuico BR.

Chest. 2013 Jun;143(6):1685-1691. doi: 10.1378/chest.12-1359.


The peroxisome proliferator-activated receptor agonist pioglitazone and 5-lipoxygenase inhibitor zileuton have no effect on lung inflammation in healthy volunteers by positron emission tomography in a single-blind placebo-controlled cohort study.

Chen DL, Huang HJ, Byers DE, Shifren A, Belikoff B, Engle JT, Arentson E, Kemp D, Phillips S, Scherrer DE, Fujiwara H, Spayd KJ, Brooks FJ, Pierce RA, Castro M, Isakow W.

PLoS One. 2018 Feb 7;13(2):e0191783. doi: 10.1371/journal.pone.0191783. eCollection 2018.


18F-FDG kinetics parameters depend on the mechanism of injury in early experimental acute respiratory distress syndrome.

de Prost N, Feng Y, Wellman T, Tucci MR, Costa EL, Musch G, Winkler T, Harris RS, Venegas JG, Chao W, Vidal Melo MF.

J Nucl Med. 2014 Nov;55(11):1871-7. doi: 10.2967/jnumed.114.140962. Epub 2014 Oct 6.


Analysis of 2-[Fluorine-18]-Fluoro-2-deoxy-D-glucose uptake kinetics in PET studies of pulmonary inflammation.

Schroeder T, Melo MF, Venegas JG.

Acad Radiol. 2011 Apr;18(4):418-23. doi: 10.1016/j.acra.2010.11.019. Epub 2011 Feb 3. Review.


Dexamethasone inhibits endotoxin-induced coagulopathy in human lungs.

Bartko J, Schoergenhofer C, Schwameis M, Buchtele N, Wojta J, Schabbauer G, Stiebellehner L, Jilma B.

J Thromb Haemost. 2016 Dec;14(12):2471-2477. doi: 10.1111/jth.13504. Epub 2016 Oct 24.


Imaging lung inflammation in a murine model of Pseudomonas infection: a positron emission tomography study.

Schuster DP, Kozlowski J, Hogue L.

Exp Lung Res. 2003 Jan-Feb;29(1):45-57.


Effects of surfactant depletion on regional pulmonary metabolic activity during mechanical ventilation.

de Prost N, Costa EL, Wellman T, Musch G, Winkler T, Tucci MR, Harris RS, Venegas JG, Vidal Melo MF.

J Appl Physiol (1985). 2011 Nov;111(5):1249-58. doi: 10.1152/japplphysiol.00311.2011. Epub 2011 Jul 28.


Micro-autoradiographic assessment of cell types contributing to 2-deoxy-2-[(18)F]fluoro-D-glucose uptake during ventilator-induced and endotoxemic lung injury.

Saha D, Takahashi K, de Prost N, Winkler T, Pinilla-Vera M, Baron RM, Vidal Melo MF.

Mol Imaging Biol. 2013 Feb;15(1):19-27. doi: 10.1007/s11307-012-0575-x.


Pulmonary FDG uptake without a CT counterpart - a pitfall in interpreting PET/CT images.

Schreiter N, Nogami M, Buchert R, Froeling V, Brenner W, Diekmann F.

Acta Radiol. 2011 Jun 1;52(5):513-5. doi: 10.1258/ar.2011.100448. Epub 2011 Mar 28.


Inter- and intrasubject variability of the inflammatory response to segmental endotoxin challenge in healthy volunteers.

Holz O, Tan L, Schaumann F, Müller M, Scholl D, Hidi R, McLeod A, Krug N, Hohlfeld JM.

Pulm Pharmacol Ther. 2015 Dec;35:50-9. doi: 10.1016/j.pupt.2015.10.011. Epub 2015 Nov 10.


Absolute quantification of regional cerebral glucose utilization in mice by 18F-FDG small animal PET scanning and 2-14C-DG autoradiography.

Toyama H, Ichise M, Liow JS, Modell KJ, Vines DC, Esaki T, Cook M, Seidel J, Sokoloff L, Green MV, Innis RB.

J Nucl Med. 2004 Aug;45(8):1398-405.

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