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Items: 1 to 20 of 100

1.

Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradation.

Mansell A, Smith R, Doyle SL, Gray P, Fenner JE, Crack PJ, Nicholson SE, Hilton DJ, O'Neill LA, Hertzog PJ.

Nat Immunol. 2006 Feb;7(2):148-55. Epub 2006 Jan 15.

PMID:
16415872
2.

Mal-function of TLRs by SOCS.

Kobayashi T, Takaesu G, Yoshimura A.

Nat Immunol. 2006 Feb;7(2):123-4. No abstract available.

PMID:
16424886
3.

Structural evaluation of BTK and PKCδ mediated phosphorylation of MAL at positions Tyr86 and Tyr106.

Paracha RZ, Ali A, Ahmad J, Hussain R, Niazi U, Muhammad SA.

Comput Biol Chem. 2014 Aug;51:22-35. doi: 10.1016/j.compbiolchem.2014.04.001. Epub 2014 Apr 20.

PMID:
24840642
4.

TLR3-mediated IFN-β gene induction is negatively regulated by the TLR adaptor MyD88 adaptor-like.

Siednienko J, Halle A, Nagpal K, Golenbock DT, Miggin SM.

Eur J Immunol. 2010 Nov;40(11):3150-60. doi: 10.1002/eji.201040547. Epub 2010 Oct 19.

5.

Suppressor of cytokine signaling (SOCS) proteins indirectly regulate toll-like receptor signaling in innate immune cells.

Baetz A, Frey M, Heeg K, Dalpke AH.

J Biol Chem. 2004 Dec 24;279(52):54708-15. Epub 2004 Oct 18.

6.

IRAK1 and IRAK4 promote phosphorylation, ubiquitination, and degradation of MyD88 adaptor-like (Mal).

Dunne A, Carpenter S, Brikos C, Gray P, Strelow A, Wesche H, Morrice N, O'Neill LA.

J Biol Chem. 2010 Jun 11;285(24):18276-82. doi: 10.1074/jbc.M109.098137. Epub 2010 Apr 16. Erratum in: J Biol Chem. 2016 Nov 18;291(47):24802.

7.

Innate immune responses to endosymbiotic Wolbachia bacteria in Brugia malayi and Onchocerca volvulus are dependent on TLR2, TLR6, MyD88, and Mal, but not TLR4, TRIF, or TRAM.

Hise AG, Daehnel K, Gillette-Ferguson I, Cho E, McGarry HF, Taylor MJ, Golenbock DT, Fitzgerald KA, Kazura JW, Pearlman E.

J Immunol. 2007 Jan 15;178(2):1068-76.

8.

Tyrosine phosphorylation of MyD88 adapter-like (Mal) is critical for signal transduction and blocked in endotoxin tolerance.

Piao W, Song C, Chen H, Wahl LM, Fitzgerald KA, O'Neill LA, Medvedev AE.

J Biol Chem. 2008 Feb 8;283(6):3109-19. Epub 2007 Dec 10.

9.

In silico approach to inhibition of signaling pathways of Toll-like receptors 2 and 4 by ST2L.

Basith S, Manavalan B, Govindaraj RG, Choi S.

PLoS One. 2011;6(8):e23989. doi: 10.1371/journal.pone.0023989. Epub 2011 Aug 29.

10.

MyD88 adapter-like (Mal) is phosphorylated by Bruton's tyrosine kinase during TLR2 and TLR4 signal transduction.

Gray P, Dunne A, Brikos C, Jefferies CA, Doyle SL, O'Neill LA.

J Biol Chem. 2006 Apr 14;281(15):10489-95. Epub 2006 Jan 26. Erratum in: J Biol Chem. 2016 Dec 9;291(50):26240.

11.

The hepatitis B e antigen (HBeAg) targets and suppresses activation of the toll-like receptor signaling pathway.

Lang T, Lo C, Skinner N, Locarnini S, Visvanathan K, Mansell A.

J Hepatol. 2011 Oct;55(4):762-9. doi: 10.1016/j.jhep.2010.12.042. Epub 2011 Feb 18.

PMID:
21334391
12.

MyD88 adapter-like (Mal)/TIRAP interaction with TRAF6 is critical for TLR2- and TLR4-mediated NF-kappaB proinflammatory responses.

Verstak B, Nagpal K, Bottomley SP, Golenbock DT, Hertzog PJ, Mansell A.

J Biol Chem. 2009 Sep 4;284(36):24192-203. doi: 10.1074/jbc.M109.023044. Epub 2009 Jul 10.

13.

Herpes simplex virus immediate-early ICP0 protein inhibits Toll-like receptor 2-dependent inflammatory responses and NF-kappaB signaling.

van Lint AL, Murawski MR, Goodbody RE, Severa M, Fitzgerald KA, Finberg RW, Knipe DM, Kurt-Jones EA.

J Virol. 2010 Oct;84(20):10802-11. doi: 10.1128/JVI.00063-10. Epub 2010 Aug 4.

14.

Phagosomal retention of Francisella tularensis results in TIRAP/Mal-independent TLR2 signaling.

Cole LE, Laird MH, Seekatz A, Santiago A, Jiang Z, Barry E, Shirey KA, Fitzgerald KA, Vogel SN.

J Leukoc Biol. 2010 Feb;87(2):275-81. doi: 10.1189/jlb.0909619. Epub 2009 Nov 4.

15.

MAPPIT analysis of early Toll-like receptor signalling events.

Ulrichts P, Tavernier J.

Immunol Lett. 2008 Mar 15;116(2):141-8. doi: 10.1016/j.imlet.2007.11.026. Epub 2008 Jan 7. Review.

PMID:
18221795
16.

A novel negative regulator for IL-1 receptor and Toll-like receptor 4.

Liew FY, Liu H, Xu D.

Immunol Lett. 2005 Jan 15;96(1):27-31. Review.

PMID:
15585304
17.

Toll-like receptor signal transduction and the tailoring of innate immunity: a role for Mal?

O'Neill LA.

Trends Immunol. 2002 Jun;23(6):296-300. Review.

PMID:
12072368
18.

Lactobacillus casei MYL01 modulates the proinflammatory state induced by ethanol in an in vitro model.

Chiu YH, Tsai JJ, Lin SL, Lin MY.

J Dairy Sci. 2014;97(4):2009-16. doi: 10.3168/jds.2013-7514. Epub 2014 Jan 31.

PMID:
24485689
19.

Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction.

Fitzgerald KA, Palsson-McDermott EM, Bowie AG, Jefferies CA, Mansell AS, Brady G, Brint E, Dunne A, Gray P, Harte MT, McMurray D, Smith DE, Sims JE, Bird TA, O'Neill LA.

Nature. 2001 Sep 6;413(6851):78-83.

PMID:
11544529
20.

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