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Items: 1 to 20 of 321

1.

Development of domain-selective angiotensin I-converting enzyme inhibitors.

Redelinghuys P, Nchinda AT, Sturrock ED.

Ann N Y Acad Sci. 2005 Nov;1056:160-75.

PMID:
16387685
2.

Roles of the two active sites of somatic angiotensin-converting enzyme in the cleavage of angiotensin I and bradykinin: insights from selective inhibitors.

Georgiadis D, Beau F, Czarny B, Cotton J, Yiotakis A, Dive V.

Circ Res. 2003 Jul 25;93(2):148-54. Epub 2003 Jun 12.

PMID:
12805239
3.

Structural determinants of RXPA380, a potent and highly selective inhibitor of the angiotensin-converting enzyme C-domain.

Georgiadis D, Cuniasse P, Cotton J, Yiotakis A, Dive V.

Biochemistry. 2004 Jun 29;43(25):8048-54.

PMID:
15209500
4.
5.

Simulated interactions between angiotensin-converting enzyme and substrate gonadotropin-releasing hormone: novel insights into domain selectivity.

Papakyriakou A, Spyroulias GA, Sturrock ED, Manessi-Zoupa E, Cordopatis P.

Biochemistry. 2007 Jul 31;46(30):8753-65. Epub 2007 Jul 3.

PMID:
17605472
6.

Crystal structure of the N domain of human somatic angiotensin I-converting enzyme provides a structural basis for domain-specific inhibitor design.

Corradi HR, Schwager SL, Nchinda AT, Sturrock ED, Acharya KR.

J Mol Biol. 2006 Mar 31;357(3):964-74. Epub 2006 Jan 31.

PMID:
16476442
7.

[Structure and function of angiotensin converting enzyme and its inhibitors].

Zhao Y, Xu C.

Sheng Wu Gong Cheng Xue Bao. 2008 Feb;24(2):171-6. Review. Chinese.

PMID:
18464595
8.

Structure of angiotensin I-converting enzyme.

Sturrock ED, Natesh R, van Rooyen JM, Acharya KR.

Cell Mol Life Sci. 2004 Nov;61(21):2677-86. Review.

PMID:
15549168
9.

Investigating the domain specificity of phosphinic inhibitors RXPA380 and RXP407 in angiotensin-converting enzyme.

Kröger WL, Douglas RG, O'Neill HG, Dive V, Sturrock ED.

Biochemistry. 2009 Sep 8;48(35):8405-12. doi: 10.1021/bi9011226.

PMID:
19658433
10.

Different contributions of the angiotensin-converting enzyme C-domain and N-domain in subjects with the angiotensin-converting enzyme II and DD genotype.

van Esch JH, van Gool JM, de Bruin RJ, Payne JR, Montgomery HE, Hectors M, Deinum J, Dive V, Jan Danser AH.

J Hypertens. 2008 Apr;26(4):706-13. doi: 10.1097/HJH.0b013e3282f465d2.

PMID:
18327080
11.

Novel ketomethylene inhibitors of angiotensin I-converting enzyme (ACE): inhibition and molecular modelling.

Redelinghuys P, Nchinda AT, Chibale K, Sturrock ED.

Biol Chem. 2006 Apr;387(4):461-6.

PMID:
16606345
12.

Positional-scanning combinatorial libraries of fluorescence resonance energy transfer peptides for defining substrate specificity of the angiotensin I-converting enzyme and development of selective C-domain substrates.

Bersanetti PA, Andrade MC, Casarini DE, Juliano MA, Nchinda AT, Sturrock ED, Juliano L, Carmona AK.

Biochemistry. 2004 Dec 21;43(50):15729-36.

PMID:
15595828
13.

Angiotensin-converting enzyme-2 (ACE2): comparative modeling of the active site, specificity requirements, and chloride dependence.

Guy JL, Jackson RM, Acharya KR, Sturrock ED, Hooper NM, Turner AJ.

Biochemistry. 2003 Nov 18;42(45):13185-92.

PMID:
14609329
14.

The two homologous domains of human angiotensin I-converting enzyme interact differently with competitive inhibitors.

Wei L, Clauser E, Alhenc-Gelas F, Corvol P.

J Biol Chem. 1992 Jul 5;267(19):13398-405.

15.
16.

Crystal structure of the human angiotensin-converting enzyme-lisinopril complex.

Natesh R, Schwager SL, Sturrock ED, Acharya KR.

Nature. 2003 Jan 30;421(6922):551-4. Epub 2003 Jan 19.

PMID:
12540854
17.

Angiotensin-converting enzyme-2: a molecular and cellular perspective.

Warner FJ, Smith AI, Hooper NM, Turner AJ.

Cell Mol Life Sci. 2004 Nov;61(21):2704-13. Review.

PMID:
15549171
18.

A computational approach to the study of the binding mode of dual ACE/NEP inhibitors.

Dimitropoulos N, Papakyriakou A, Dalkas GA, Sturrock ED, Spyroulias GA.

J Chem Inf Model. 2010 Mar 22;50(3):388-96. doi: 10.1021/ci9005047.

PMID:
20170101
19.
20.

The influence of angiotensin converting enzyme mutations on the kinetics and dynamics of N-domain selective inhibition.

Lubbe L, Sewell BT, Sturrock ED.

FEBS J. 2016 Nov;283(21):3941-3961. doi: 10.1111/febs.13900. Epub 2016 Oct 5.

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