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Items: 1 to 20 of 99

1.

ERK1/2 mitogen-activated protein kinase selectively mediates IL-13-induced lung inflammation and remodeling in vivo.

Lee PJ, Zhang X, Shan P, Ma B, Lee CG, Homer RJ, Zhu Z, Rincon M, Mossman BT, Elias JA.

J Clin Invest. 2006 Jan;116(1):163-73. Epub 2005 Dec 22.

2.

Role of early growth response-1 (Egr-1) in interleukin-13-induced inflammation and remodeling.

Cho SJ, Kang MJ, Homer RJ, Kang HR, Zhang X, Lee PJ, Elias JA, Lee CG.

J Biol Chem. 2006 Mar 24;281(12):8161-8. Epub 2006 Jan 26.

3.

The C10/CCL6 chemokine and CCR1 play critical roles in the pathogenesis of IL-13-induced inflammation and remodeling.

Ma B, Zhu Z, Homer RJ, Gerard C, Strieter R, Elias JA.

J Immunol. 2004 Feb 1;172(3):1872-81.

4.

Corticosteroid and doxycycline suppress MMP-9 and inflammatory cytokine expression, MAPK activation in the corneal epithelium in experimental dry eye.

De Paiva CS, Corrales RM, Villarreal AL, Farley WJ, Li DQ, Stern ME, Pflugfelder SC.

Exp Eye Res. 2006 Sep;83(3):526-35. Epub 2006 Apr 27.

PMID:
16643899
5.

Transgenic overexpression of interleukin (IL)-10 in the lung causes mucus metaplasia, tissue inflammation, and airway remodeling via IL-13-dependent and -independent pathways.

Lee CG, Homer RJ, Cohn L, Link H, Jung S, Craft JE, Graham BS, Johnson TR, Elias JA.

J Biol Chem. 2002 Sep 20;277(38):35466-74. Epub 2002 Jul 9.

6.

IL-4 is a critical determinant in the generation of allergic inflammation initiated by a constitutively active Stat6.

Sehra S, Bruns HA, Ahyi AN, Nguyen ET, Schmidt NW, Michels EG, von Bülow GU, Kaplan MH.

J Immunol. 2008 Mar 1;180(5):3551-9.

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Mechanical stress-mediated Runx2 activation is dependent on Ras/ERK1/2 MAPK signaling in osteoblasts.

Kanno T, Takahashi T, Tsujisawa T, Ariyoshi W, Nishihara T.

J Cell Biochem. 2007 Aug 1;101(5):1266-77.

PMID:
17265428
10.

Phosphatase-mediated crosstalk control of ERK and p38 MAPK signaling in corneal epithelial cells.

Wang Z, Yang H, Tachado SD, Capó-Aponte JE, Bildin VN, Koziel H, Reinach PS.

Invest Ophthalmol Vis Sci. 2006 Dec;47(12):5267-75.

PMID:
17122112
11.

Sustained versus transient ERK1/2 signaling underlies the anti- and proapoptotic effects of oxidative stress in human RPE cells.

Glotin AL, Calipel A, Brossas JY, Faussat AM, Tréton J, Mascarelli F.

Invest Ophthalmol Vis Sci. 2006 Oct;47(10):4614-23.

PMID:
17003459
13.

Interleukin-1alpha stimulates proinflammatory cytokine expression in human cardiac myofibroblasts.

Turner NA, Das A, Warburton P, O'Regan DJ, Ball SG, Porter KE.

Am J Physiol Heart Circ Physiol. 2009 Sep;297(3):H1117-27. doi: 10.1152/ajpheart.00372.2009. Epub 2009 Jul 31.

14.

Genetic deletion of PKR abrogates TNF-induced activation of IkappaBalpha kinase, JNK, Akt and cell proliferation but potentiates p44/p42 MAPK and p38 MAPK activation.

Takada Y, Ichikawa H, Pataer A, Swisher S, Aggarwal BB.

Oncogene. 2007 Feb 22;26(8):1201-12. Epub 2006 Aug 21.

PMID:
16924232
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Prostaglandin E1 inhibits IL-6-induced MCP-1 expression by interfering specifically in IL-6-dependent ERK1/2, but not STAT3, activation.

Sobota RM, Müller PJ, Heinrich PC, Schaper F.

Biochem J. 2008 May 15;412(1):65-72. doi: 10.1042/BJ20071572.

PMID:
18271757
19.

Opposing actions of Stat1 and Stat6 on IL-13-induced up-regulation of early growth response-1 and platelet-derived growth factor ligands in pulmonary fibroblasts.

Ingram JL, Antao-Menezes A, Mangum JB, Lyght O, Lee PJ, Elias JA, Bonner JC.

J Immunol. 2006 Sep 15;177(6):4141-8.

20.

IL-18 is induced and IL-18 receptor alpha plays a critical role in the pathogenesis of cigarette smoke-induced pulmonary emphysema and inflammation.

Kang MJ, Homer RJ, Gallo A, Lee CG, Crothers KA, Cho SJ, Rochester C, Cain H, Chupp G, Yoon HJ, Elias JA.

J Immunol. 2007 Feb 1;178(3):1948-59.

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