Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 144


Molecular cloning, expression, and structural prediction of deoxyhypusine hydroxylase: a HEAT-repeat-containing metalloenzyme.

Park JH, Aravind L, Wolff EC, Kaevel J, Kim YS, Park MH.

Proc Natl Acad Sci U S A. 2006 Jan 3;103(1):51-6. Epub 2005 Dec 21.


A unique modification of the eukaryotic initiation factor 5A shows the presence of the complete hypusine pathway in Leishmania donovani.

Chawla B, Kumar RR, Tyagi N, Subramanian G, Srinivasan N, Park MH, Madhubala R.

PLoS One. 2012;7(3):e33138. doi: 10.1371/journal.pone.0033138. Epub 2012 Mar 16.


Deoxyhypusine hydroxylase is a Fe(II)-dependent, HEAT-repeat enzyme. Identification of amino acid residues critical for Fe(II) binding and catalysis [corrected].

Kim YS, Kang KR, Wolff EC, Bell JK, McPhie P, Park MH.

J Biol Chem. 2006 May 12;281(19):13217-25. Epub 2006 Mar 13. Erratum in: J Biol Chem. 2007 Apr 6;282(14):10840.


Production of active recombinant eIF5A: reconstitution in E.coli of eukaryotic hypusine modification of eIF5A by its coexpression with modifying enzymes.

Park JH, Dias CA, Lee SB, Valentini SR, Sokabe M, Fraser CS, Park MH.

Protein Eng Des Sel. 2011 Mar;24(3):301-9. doi: 10.1093/protein/gzq110. Epub 2010 Dec 2.


Posttranslational synthesis of hypusine: evolutionary progression and specificity of the hypusine modification.

Wolff EC, Kang KR, Kim YS, Park MH.

Amino Acids. 2007 Aug;33(2):341-50. Epub 2007 May 4. Review.


Molecular cloning and functional expression of bovine deoxyhypusine hydroxylase cDNA and homologs.

Huang JK, Cui Y, Chen CH, Clampitt D, Lin CT, Wen L.

Protein Expr Purif. 2007 Jul;54(1):126-33. Epub 2007 Feb 21.


Functional significance of eIF5A and its hypusine modification in eukaryotes.

Park MH, Nishimura K, Zanelli CF, Valentini SR.

Amino Acids. 2010 Feb;38(2):491-500. doi: 10.1007/s00726-009-0408-7. Epub 2009 Dec 8. Review.


Essential role of eIF5A-1 and deoxyhypusine synthase in mouse embryonic development.

Nishimura K, Lee SB, Park JH, Park MH.

Amino Acids. 2012 Feb;42(2-3):703-10. doi: 10.1007/s00726-011-0986-z. Epub 2011 Aug 18.


Deoxyhypusine hydroxylase from Plasmodium vivax, the neglected human malaria parasite: molecular cloning, expression and specific inhibition by the 5-LOX inhibitor zileuton.

Atemnkeng VA, Pink M, Schmitz-Spanke S, Wu XJ, Dong LL, Zhao KH, May C, Laufer S, Langer B, Kaiser A.

PLoS One. 2013;8(3):e58318. doi: 10.1371/journal.pone.0058318. Epub 2013 Mar 7.


Assay of deoxyhypusine hydroxylase activity.

Park JH, Wolff EC, Park MH.

Methods Mol Biol. 2011;720:207-16. doi: 10.1007/978-1-61779-034-8_13.


Completing the hypusine pathway in Plasmodium.

Frommholz D, Kusch P, Blavid R, Scheer H, Tu JM, Marcus K, Zhao KH, Atemnkeng V, Marciniak J, Kaiser AE.

FEBS J. 2009 Oct;276(20):5881-91. doi: 10.1111/j.1742-4658.2009.07272.x. Epub 2009 Sep 9.


Molecular cloning of bovine eIF5A and deoxyhypusine synthase cDNA.

Huang JK, Tsai S, Huang GH, Sershon VC, Alley AM, Wen L.

DNA Seq. 2004 Feb;15(1):26-32.


Mutational analyses of human eIF5A-1--identification of amino acid residues critical for eIF5A activity and hypusine modification.

Cano VS, Jeon GA, Johansson HE, Henderson CA, Park JH, Valentini SR, Hershey JW, Park MH.

FEBS J. 2008 Jan;275(1):44-58. Epub 2007 Dec 6.


Evidence for conformational changes in the yeast deoxyhypusine hydroxylase Lia1 upon iron displacement from its active site.

Cano VS, Medrano FJ, Park MH, Valentini SR.

Amino Acids. 2010 Feb;38(2):479-90. doi: 10.1007/s00726-009-0407-8. Epub 2009 Dec 3.


Higher activity of recombinant bovine deoxyhypusine synthase vs. human deoxyhypusine synthase.

Huang JK, Tsai S, Huang GH, Gowda PG, Walzer AM, Wen L.

Protein Expr Purif. 2004 May;35(1):32-8.


Identification and characterization of eukaryotic initiation factor 5A-2.

Clement PM, Henderson CA, Jenkins ZA, Smit-McBride Z, Wolff EC, Hershey JW, Park MH, Johansson HE.

Eur J Biochem. 2003 Nov;270(21):4254-63.


The Drosophila deoxyhypusine hydroxylase homologue nero and its target eIF5A are required for cell growth and the regulation of autophagy.

Patel PH, Costa-Mattioli M, Schulze KL, Bellen HJ.

J Cell Biol. 2009 Jun 29;185(7):1181-94. doi: 10.1083/jcb.200904161. Epub 2009 Jun 22.

Supplemental Content

Support Center