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16357012,17311893,18510711,16219667,12954596,19625692,21463259,15186996,19141681,18238811,15161924,17478525,16670153,22030855,16464906,9566999,15647392,12464674,20484014,17179390,15383373,22653277,11934665,20006584,19138173,22967501,15132977,12864744,15449958,10913024,16203972,16925851,27941154,10422724,15515015,12067844,9710806,17374701,25103967,9344464,11073569,12479588,17264223,23039229,12079850,11912554,21041527,27507552,19448712,23031491,15814607,17170203,11329295,9693125,12540388,22928974,20837491,2166437,23537026,19429947,25713059,12611761,17234801,15140757,15677504,18081885,23902784,10856709,18772848,10909961,10651636,9349840,23221957,9546638,11432762,24558043,3977825,27647415,22584574,22028411,16198626,32295037,23519231,16718359,19088769,27827305,11090589,25259652,25766930,12864750,1227502,24469765,11788383,11052958,18359285,12826662,20237302,9611159,10212840,30635360,16030063,29221849,10721894,8141397,15220187,10710500,24350597,19675275,9142886,22463611,28035013,18349111,12864739,27806984,11739099,23548615,21442160,12206997,23545469,22071161,21541677,26056297,9781332,9886945,8013751,7487941,24845952,15669760,10623482,27399985,2009609,20962926,11409158,17904092,9781331,9655768,16904672,35101729,31788014,18974364,15496455,27685008,20352092,11595663,20117238,7572222,27892502,11814524,26164228,3569293,31906370,21596918,29232696,22923231,1356769,15579906,12706342,11551846,22982985,14602787,6319070,20682693,16753149,15208282,11356163,12079837,11681722,3361755,30168279,25261498,9843740,12540837,8566378,20333349,3927008,19017764,30111574,16868746,22938691,11790778,23139350,23426616,18292295,8216240,25398709,7760380,12800100,31161881,15592483,19056573,2316720,10995775,25965390,10092622,15155715,22078938,14694205,32543943,35044230,11551858,9390963,28419197,12626325,18937505,17331998,21816445,16984983,31973165,25670828,25163918,29401600,16651524,8638703,19228984,22890711,28676454,9725814,25070011,23287371,20103701,10950823,19073774,3311010,29626373,4076518,24503477,27337034,7066363,2055826,11736689,12565845,26156967,2558099,12351641,31112997,30975900,9546635,26226763,23525500,10799533,9053394,10759584,6615873,24858472,34562114,19448717,24625643,12618083,3122591,30935113,26245899,19675136,3210537,25845660,26486368,18416593,23512741,18511526,33675111,10544243,12089210,8335590,11120668,22127648,31589831,7448619,33903888,11595646,26475290,12351456,8313432,11915935,10367719,14732484,17034771,8435437,5722681,11579177,19808840,28547918,29037265,28158621,9277379,12231658,19396472,12969881,15191896,10976758,28830979,10923628,30204501,33770195,30218613,30933285,10409247,8941640,23036730,10407779,17548828,26995156,23673156,27730694,23818692,25213552,9950796,17456847,30219858,14740222,19258660,12458396,11742827,21681225,24815572,9781330,11141076,1141213,16899801,7734439,8872662,11751291,31097541,22547424,22322067,25091629,21153644,15577262,7929825,26638980,35955635,12218742,9781329,19245653,27195673,22235293,11991847,18247111,3119934,32985255,6212234,18059611,26000608,3197828,30363008,497040,20363655,22976767,28150475,28251664,1998535,9893016,25054452,24791920,15238213,11959683,6592996,11009433,2564395,10801831,9781322,25363063,1936236,33464721,26546819,6284242,19448703,11713642,10448533,19553674,12915209,9572831,3210541,12969874,7767092,32369416,26416973,5096516,23873132,29844861,14748718,12672928,15516711,9140901,15897321,32102800,25277110,3520914,30912279,12096068,28580772,21289287,11286278,17761175,24905907,16541201,27941349,24488024,30043752,2593489,22022213,8085267,11133888,12086953,23047988,8610095,23463651,9931175,10638339,8806937,34610308,24368672,638156,27488889,21592121,833674,17431090,438852,14622442,9497160,1407693,22527602,32812929,18214656,32562386,36615118,19369366,9788250,28090559,29980534,23785078,31866205,12530530,34350838,31652245,9680378,24374928,20023206,508289,24984811,18396088,29663395,8857706,32055177,31584947,22457744,20032466,22735180,26995462,28883917,7159410,22223579,12761301,29513564,29240609,26830498,17303684,28526781,35138177,22271865,12052217,6225030,15002531,30924938,20634953,28854364,6891604,12464664,33937992,36722264,12739165,11158934,23967116,21659500,2501584,21900644,14729862,173805,8523423,21085477,16799133,37053180,8475892,11880112,32796254,10827346,10919968,31305240,32255679,1945750,17558605,21888528,24253653,33570804,18639661,21934122,24128929,29204295,22898252,27401086,11028683,34220709,18948552,34436463,12062187,7412506,17451602,27757385,2732662,35991116,24632837,29949755,8997224,16930355,11399900,25741892,6618942,31990577,24232030,8958141,28955844,35362801,6246475,3428477,2251266,14970749,36917141,12224819,31240159,34706104,29317762,36111143,36408830,19423832,33099002,19924273,2973105,36732635,22096123,25318747,21210569,1568268,26923548,31309577,33559031,34945671,34408664,6142097,36979708,15547301,21210568,668914,29590556,4441743,25484869,24970143,26185606,31320983,34947924,22816722,32850342,32608126,31279855,8359429,24424908,21383874,36693836,26059033,12108259,36346511,28150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Mitochondrial long chain fatty acid oxidation, fatty acid translocase/CD36 content and carnitine palmitoyltransferase I activity in human skeletal muscle during aerobic exercise.

Holloway GP, Bezaire V, Heigenhauser GJ, Tandon NN, Glatz JF, Luiken JJ, Bonen A, Spriet LL. Holloway GP, et al. J Physiol. 2006 Feb 15;571(Pt 1):201-10. doi: 10.1113/jphysiol.2005.102178. Epub 2005 Dec 15. J Physiol. 2006. PMID: 16357012 Free PMC article.

Skeletal muscle mitochondrial FAT/CD36 content and palmitate oxidation are not decreased in obese women.

Holloway GP, Thrush AB, Heigenhauser GJ, Tandon NN, Dyck DJ, Bonen A, Spriet LL. Holloway GP, et al. Am J Physiol Endocrinol Metab. 2007 Jun;292(6):E1782-9. doi: 10.1152/ajpendo.00639.2006. Epub 2007 Feb 20. Am J Physiol Endocrinol Metab. 2007. PMID: 17311893 Free article.

Contribution of FAT/CD36 to the regulation of skeletal muscle fatty acid oxidation: an overview.

Holloway GP, Luiken JJ, Glatz JF, Spriet LL, Bonen A. Holloway GP, et al. Acta Physiol (Oxf). 2008 Dec;194(4):293-309. doi: 10.1111/j.1748-1716.2008.01878.x. Epub 2008 Jul 9. Acta Physiol (Oxf). 2008. PMID: 18510711 Review.

Identification of fatty acid translocase on human skeletal muscle mitochondrial membranes: essential role in fatty acid oxidation.

Bezaire V, Bruce CR, Heigenhauser GJ, Tandon NN, Glatz JF, Luiken JJ, Bonen A, Spriet LL. Bezaire V, et al. Am J Physiol Endocrinol Metab. 2006 Mar;290(3):E509-15. doi: 10.1152/ajpendo.00312.2005. Epub 2005 Oct 11. Am J Physiol Endocrinol Metab. 2006. PMID: 16219667 Free article.

Regulation of CPT I activity in intermyofibrillar and subsarcolemmal mitochondria from human and rat skeletal muscle.

Bezaire V, Heigenhauser GJ, Spriet LL. Bezaire V, et al. Am J Physiol Endocrinol Metab. 2004 Jan;286(1):E85-91. doi: 10.1152/ajpendo.00237.2003. Epub 2003 Sep 3. Am J Physiol Endocrinol Metab. 2004. PMID: 12954596 Free article. Clinical Trial.

FAT/CD36-null mice reveal that mitochondrial FAT/CD36 is required to upregulate mitochondrial fatty acid oxidation in contracting muscle.

Holloway GP, Jain SS, Bezaire V, Han XX, Glatz JF, Luiken JJ, Harper ME, Bonen A. Holloway GP, et al. Am J Physiol Regul Integr Comp Physiol. 2009 Oct;297(4):R960-7. doi: 10.1152/ajpregu.91021.2008. Epub 2009 Jul 22. Am J Physiol Regul Integr Comp Physiol. 2009. PMID: 19625692 Free article.

FAT/CD36 is located on the outer mitochondrial membrane, upstream of long-chain acyl-CoA synthetase, and regulates palmitate oxidation.

Smith BK, Jain SS, Rimbaud S, Dam A, Quadrilatero J, Ventura-Clapier R, Bonen A, Holloway GP. Smith BK, et al. Biochem J. 2011 Jul 1;437(1):125-34. doi: 10.1042/BJ20101861. Biochem J. 2011. PMID: 21463259

Regulation of plasma long-chain fatty acid oxidation in relation to uptake in human skeletal muscle during exercise.

Roepstorff C, Vistisen B, Roepstorff K, Kiens B. Roepstorff C, et al. Am J Physiol Endocrinol Metab. 2004 Oct;287(4):E696-705. doi: 10.1152/ajpendo.00001.2004. Epub 2004 Jun 8. Am J Physiol Endocrinol Metab. 2004. PMID: 15186996 Free article. Clinical Trial.

In obese rat muscle transport of palmitate is increased and is channeled to triacylglycerol storage despite an increase in mitochondrial palmitate oxidation.

Holloway GP, Benton CR, Mullen KL, Yoshida Y, Snook LA, Han XX, Glatz JF, Luiken JJ, Lally J, Dyck DJ, Bonen A. Holloway GP, et al. Am J Physiol Endocrinol Metab. 2009 Apr;296(4):E738-47. doi: 10.1152/ajpendo.90896.2008. Epub 2009 Jan 13. Am J Physiol Endocrinol Metab. 2009. PMID: 19141681 Free article.

Rosiglitazone increases fatty acid oxidation and fatty acid translocase (FAT/CD36) but not carnitine palmitoyltransferase I in rat muscle mitochondria.

Benton CR, Holloway GP, Campbell SE, Yoshida Y, Tandon NN, Glatz JF, Luiken JJ, Spriet LL, Bonen A. Benton CR, et al. J Physiol. 2008 Mar 15;586(6):1755-66. doi: 10.1113/jphysiol.2007.146563. Epub 2008 Jan 31. J Physiol. 2008. PMID: 18238811 Free PMC article.

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