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Items: 1 to 20 of 133


Physical and functional interactions of the cytomegalovirus US6 glycoprotein with the transporter associated with antigen processing.

Halenius A, Momburg F, Reinhard H, Bauer D, Lobigs M, Hengel H.

J Biol Chem. 2006 Mar 3;281(9):5383-90. Epub 2005 Dec 15.


Head-head/tail-tail relative orientation of the pore-forming domains of the heterodimeric ABC transporter TAP.

Vos JC, Reits EA, Wojcik-Jacobs E, Neefjes J.

Curr Biol. 2000 Jan 13;10(1):1-7.


Biogenesis of functional antigenic peptide transporter TAP requires assembly of pre-existing TAP1 with newly synthesized TAP2.

Keusekotten K, Leonhardt RM, Ehses S, Knittler MR.

J Biol Chem. 2006 Jun 30;281(26):17545-51. Epub 2006 Apr 19.


Structural and Functional Dissection of the Human Cytomegalovirus Immune Evasion Protein US6.

Dugan GE, Hewitt EW.

J Virol. 2008 Apr;82(7):3271-82. doi: 10.1128/JVI.01705-07. Epub 2008 Jan 16.


The varicellovirus UL49.5 protein blocks the transporter associated with antigen processing (TAP) by inhibiting essential conformational transitions in the 6+6 transmembrane TAP core complex.

Verweij MC, Koppers-Lalic D, Loch S, Klauschies F, de la Salle H, Quinten E, Lehner PJ, Mulder A, Knittler MR, Tampé R, Koch J, Ressing ME, Wiertz EJ.

J Immunol. 2008 Oct 1;181(7):4894-907.


Tapasin interacts with the membrane-spanning domains of both TAP subunits and enhances the structural stability of TAP1 x TAP2 Complexes.

Raghuraman G, Lapinski PE, Raghavan M.

J Biol Chem. 2002 Nov 1;277(44):41786-94. Epub 2002 Sep 3.


The ER-luminal domain of the HCMV glycoprotein US6 inhibits peptide translocation by TAP.

Ahn K, Gruhler A, Galocha B, Jones TR, Wiertz EJ, Ploegh HL, Peterson PA, Yang Y, Früh K.

Immunity. 1997 May;6(5):613-21.


Functional role of C-terminal sequence elements in the transporter associated with antigen processing.

Ehses S, Leonhardt RM, Hansen G, Knittler MR.

J Immunol. 2005 Jan 1;174(1):328-39.


The human cytomegalovirus gene product US6 inhibits ATP binding by TAP.

Hewitt EW, Gupta SS, Lehner PJ.

EMBO J. 2001 Feb 1;20(3):387-96.


Functional dissection of the transmembrane domains of the transporter associated with antigen processing (TAP).

Koch J, Guntrum R, Heintke S, Kyritsis C, Tampé R.

J Biol Chem. 2004 Mar 12;279(11):10142-7. Epub 2003 Dec 15.


Dependence of the localization and function of the human cytomegalovirus protein US6 on the transporter associated with antigen processing.

Dugan GE, Hewitt EW.

J Gen Virol. 2009 Sep;90(Pt 9):2234-8. doi: 10.1099/vir.0.012757-0. Epub 2009 May 13.


Identification of sequences in the human peptide transporter subunit TAP1 required for transporter associated with antigen processing (TAP) function.

Ritz U, Momburg F, Pircher HP, Strand D, Huber C, Seliger B.

Int Immunol. 2001 Jan;13(1):31-41.


Peptides induce ATP hydrolysis at both subunits of the transporter associated with antigen processing.

Chen M, Abele R, Tampé R.

J Biol Chem. 2003 Aug 8;278(32):29686-92. Epub 2003 May 30.

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