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Items: 1 to 20 of 133

1.

Inhibition of SIRT1 catalytic activity increases p53 acetylation but does not alter cell survival following DNA damage.

Solomon JM, Pasupuleti R, Xu L, McDonagh T, Curtis R, DiStefano PS, Huber LJ.

Mol Cell Biol. 2006 Jan;26(1):28-38.

2.

Measurement of the cellular deacetylase activity of SIRT1 on p53 via LanthaScreen® technology.

Robers MB, Loh C, Carlson CB, Yang H, Frey EA, Hermanson SB, Bi K.

Mol Biosyst. 2011 Jan;7(1):59-66. doi: 10.1039/c0mb00026d. Epub 2010 Oct 8.

PMID:
20931131
3.

Silent information regulator 2alpha, a longevity factor and class III histone deacetylase, is an essential endogenous apoptosis inhibitor in cardiac myocytes.

Alcendor RR, Kirshenbaum LA, Imai S, Vatner SF, Sadoshima J.

Circ Res. 2004 Nov 12;95(10):971-80. Epub 2004 Oct 14.

4.

HIPK2 modulates p53 activity towards pro-apoptotic transcription.

Puca R, Nardinocchi L, Sacchi A, Rechavi G, Givol D, D'Orazi G.

Mol Cancer. 2009 Oct 14;8:85. doi: 10.1186/1476-4598-8-85.

5.

Active regulator of SIRT1 cooperates with SIRT1 and facilitates suppression of p53 activity.

Kim EJ, Kho JH, Kang MR, Um SJ.

Mol Cell. 2007 Oct 26;28(2):277-90. Erratum in: Mol Cell. 2007 Nov 9;28(3):513.

6.

Necdin regulates p53 acetylation via Sirtuin1 to modulate DNA damage response in cortical neurons.

Hasegawa K, Yoshikawa K.

J Neurosci. 2008 Aug 27;28(35):8772-84. doi: 10.1523/JNEUROSCI.3052-08.2008.

7.

H2O2 accelerates cellular senescence by accumulation of acetylated p53 via decrease in the function of SIRT1 by NAD+ depletion.

Furukawa A, Tada-Oikawa S, Kawanishi S, Oikawa S.

Cell Physiol Biochem. 2007;20(1-4):45-54.

8.

Opposing effects of hMOF and SIRT1 on H4K16 acetylation and the sensitivity to the topoisomerase II inhibitor etoposide.

Hajji N, Wallenborg K, Vlachos P, Füllgrabe J, Hermanson O, Joseph B.

Oncogene. 2010 Apr 15;29(15):2192-204. doi: 10.1038/onc.2009.505. Epub 2010 Feb 1.

PMID:
20118981
9.

Inhibition of histone deacetylase increases cytotoxicity to anticancer drugs targeting DNA.

Kim MS, Blake M, Baek JH, Kohlhagen G, Pommier Y, Carrier F.

Cancer Res. 2003 Nov 1;63(21):7291-300.

10.
11.

Deacetylase inhibition in malignant melanomas: impact on cell cycle regulation and survival.

Flørenes VA, Skrede M, Jørgensen K, Nesland JM.

Melanoma Res. 2004 Jun;14(3):173-81.

PMID:
15179185
12.

Sirtinol, a class III HDAC inhibitor, induces apoptotic and autophagic cell death in MCF-7 human breast cancer cells.

Wang J, Kim TH, Ahn MY, Lee J, Jung JH, Choi WS, Lee BM, Yoon KS, Yoon S, Kim HS.

Int J Oncol. 2012 Sep;41(3):1101-9. doi: 10.3892/ijo.2012.1534. Epub 2012 Jun 26.

PMID:
22751989
13.

Sensitization to UV-induced apoptosis by the histone deacetylase inhibitor trichostatin A (TSA).

Kim MS, Baek JH, Chakravarty D, Sidransky D, Carrier F.

Exp Cell Res. 2005 May 15;306(1):94-102. Epub 2005 Mar 19.

PMID:
15878336
14.

Induction of PIG3 and NOXA through acetylation of p53 at 320 and 373 lysine residues as a mechanism for apoptotic cell death by histone deacetylase inhibitors.

Terui T, Murakami K, Takimoto R, Takahashi M, Takada K, Murakami T, Minami S, Matsunaga T, Takayama T, Kato J, Niitsu Y.

Cancer Res. 2003 Dec 15;63(24):8948-54.

16.

A novel chalcone polyphenol inhibits the deacetylase activity of SIRT1 and cell growth in HEK293T cells.

Kahyo T, Ichikawa S, Hatanaka T, Yamada MK, Setou M.

J Pharmacol Sci. 2008 Nov;108(3):364-71. Epub 2008 Nov 13.

17.

Histone deacetylase inhibitor-induced cellular apoptosis involves stanniocalcin-1 activation.

Law AY, Lai KP, Lui WC, Wan HT, Wong CK.

Exp Cell Res. 2008 Oct 1;314(16):2975-84. doi: 10.1016/j.yexcr.2008.07.002. Epub 2008 Jul 9.

PMID:
18652825
18.

HDAC gene expression in pancreatic tumor cell lines following treatment with the HDAC inhibitors panobinostat (LBH589) and trichostatine (TSA).

Mehdi O, Françoise S, Sofia CL, Urs G, Kevin Z, Bernard S, Igor S, Anabela CD, Dominique L, Eric M, Ali O.

Pancreatology. 2012 Mar-Apr;12(2):146-55. doi: 10.1016/j.pan.2012.02.013. Epub 2012 Feb 25.

PMID:
22487525
19.

The inhibitor of growth 1 (ING1) is involved in trichostatin A-induced apoptosis and caspase 3 signaling in p53-deficient glioblastoma cells.

Tamannai M, Farhangi S, Truss M, Sinn B, Wurm R, Bose P, Henze G, Riabowol K, von Deimling A, Tallen G.

Oncol Res. 2010;18(10):469-80.

PMID:
20681406
20.

Trichostatin A inhibits proliferation and induces expression of p21WAF and p27 in human brain tumor cell lines.

Wang ZM, Hu J, Zhou D, Xu ZY, Panasci LC, Chen ZP.

Ai Zheng. 2002 Oct;21(10):1100-5.

PMID:
12508652

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