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Items: 1 to 20 of 184

1.

Novel seizure phenotype and sleep disruptions in knock-in mice with hypersensitive alpha 4* nicotinic receptors.

Fonck C, Cohen BN, Nashmi R, Whiteaker P, Wagenaar DA, Rodrigues-Pinguet N, Deshpande P, McKinney S, Kwoh S, Munoz J, Labarca C, Collins AC, Marks MJ, Lester HA.

J Neurosci. 2005 Dec 7;25(49):11396-411.

2.

Alpha4* nicotinic receptors in preBotzinger complex mediate cholinergic/nicotinic modulation of respiratory rhythm.

Shao XM, Tan W, Xiu J, Puskar N, Fonck C, Lester HA, Feldman JL.

J Neurosci. 2008 Jan 9;28(2):519-28. doi: 10.1523/JNEUROSCI.3666-07.2008.

4.

Increased sensitivity to agonist-induced seizures, straub tail, and hippocampal theta rhythm in knock-in mice carrying hypersensitive alpha 4 nicotinic receptors.

Fonck C, Nashmi R, Deshpande P, Damaj MI, Marks MJ, Riedel A, Schwarz J, Collins AC, Labarca C, Lester HA.

J Neurosci. 2003 Apr 1;23(7):2582-90.

5.

Mice expressing the ADNFLE valine 287 leucine mutation of the Β2 nicotinic acetylcholine receptor subunit display increased sensitivity to acute nicotine administration and altered presynaptic nicotinic receptor function.

O'Neill HC, Laverty DC, Patzlaff NE, Cohen BN, Fonck C, McKinney S, McIntosh JM, Lindstrom JM, Lester HA, Grady SR, Marks MJ.

Pharmacol Biochem Behav. 2013 Jan;103(3):603-21. doi: 10.1016/j.pbb.2012.10.014. Epub 2012 Nov 1.

6.

Human nocturnal frontal lobe epilepsy: pharmocogenomic profiles of pathogenic nicotinic acetylcholine receptor beta-subunit mutations outside the ion channel pore.

Hoda JC, Gu W, Friedli M, Phillips HA, Bertrand S, Antonarakis SE, Goudie D, Roberts R, Scheffer IE, Marini C, Patel J, Berkovic SF, Mulley JC, Steinlein OK, Bertrand D.

Mol Pharmacol. 2008 Aug;74(2):379-91. doi: 10.1124/mol.107.044545. Epub 2008 May 2.

7.

Mutation (Ser284Leu) of neuronal nicotinic acetylcholine receptor alpha 4 subunit associated with frontal lobe epilepsy causes faster desensitization of the rat receptor expressed in oocytes.

Matsushima N, Hirose S, Iwata H, Fukuma G, Yonetani M, Nagayama C, Hamanaka W, Matsunaka Y, Ito M, Kaneko S, Mitsudome A, Sugiyama H.

Epilepsy Res. 2002 Feb;48(3):181-6.

PMID:
11904236
8.

CHRNB2 is the second acetylcholine receptor subunit associated with autosomal dominant nocturnal frontal lobe epilepsy.

Phillips HA, Favre I, Kirkpatrick M, Zuberi SM, Goudie D, Heron SE, Scheffer IE, Sutherland GR, Berkovic SF, Bertrand D, Mulley JC.

Am J Hum Genet. 2001 Jan;68(1):225-31. Epub 2000 Dec 5.

9.

Potential role of the alpha4 and alpha6 nicotinic receptor subunits in regulating nicotine-induced seizures.

Stitzel JA, Jimenez M, Marks MJ, Tritto T, Collins AC.

J Pharmacol Exp Ther. 2000 Apr;293(1):67-74.

10.
11.

Alpha 4 beta 2* nicotinic acetylcholine receptors modulate the effects of ethanol and nicotine on the acoustic startle response.

Owens JC, Balogh SA, McClure-Begley TD, Butt CM, Labarca C, Lester HA, Picciotto MR, Wehner JM, Collins AC.

Alcohol Clin Exp Res. 2003 Dec;27(12):1867-75.

PMID:
14691373
12.
13.

Expression changes in mouse brains following nicotine-induced seizures: the modulation of transcription factor networks.

Kedmi M, Orr-Urtreger A.

Physiol Genomics. 2007 Aug 20;30(3):242-52. Epub 2007 Apr 24.

PMID:
17456735
14.

Rats harboring S284L Chrna4 mutation show attenuation of synaptic and extrasynaptic GABAergic transmission and exhibit the nocturnal frontal lobe epilepsy phenotype.

Zhu G, Okada M, Yoshida S, Ueno S, Mori F, Takahara T, Saito R, Miura Y, Kishi A, Tomiyama M, Sato A, Kojima T, Fukuma G, Wakabayashi K, Hase K, Ohno H, Kijima H, Takano Y, Mitsudome A, Kaneko S, Hirose S.

J Neurosci. 2008 Nov 19;28(47):12465-76. doi: 10.1523/JNEUROSCI.2961-08.2008.

15.

The alpha3 and beta4 nicotinic acetylcholine receptor subunits are necessary for nicotine-induced seizures and hypolocomotion in mice.

Salas R, Cook KD, Bassetto L, De Biasi M.

Neuropharmacology. 2004 Sep;47(3):401-7. Erratum in: Neuropharmacology. 2004 Dec;47(7):1113.

PMID:
15275829
16.

Electroencephalographic characterisation of pentylenetetrazole-induced seizures in mice lacking the alpha 4 subunit of the neuronal nicotinic receptor.

McColl CD, Horne MK, Finkelstein DI, Wong JY, Berkovic SF, Drago J.

Neuropharmacology. 2003 Feb;44(2):234-43.

PMID:
12623222
17.

The role of the nicotinic acetylcholine receptors in sleep-related epilepsy.

Marini C, Guerrini R.

Biochem Pharmacol. 2007 Oct 15;74(8):1308-14. Epub 2007 Jun 23. Review.

PMID:
17662253
18.
19.

Genetic and pharmacological strategies identify a behavioral function of neuronal nicotinic receptors.

Stitzel JA, Lu Y, Jimenez M, Tritto T, Collins AC.

Behav Brain Res. 2000 Aug;113(1-2):57-64.

PMID:
10942032
20.

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