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The Polycomb group protein EZH2 impairs DNA repair in breast epithelial cells.

Zeidler M, Varambally S, Cao Q, Chinnaiyan AM, Ferguson DO, Merajver SD, Kleer CG.

Neoplasia. 2005 Nov;7(11):1011-9.


The Polycomb group protein Enhancer of Zeste 2: its links to DNA repair and breast cancer.

Zeidler M, Kleer CG.

J Mol Histol. 2006 Sep;37(5-7):219-23. Review.


EZH2 promotes expansion of breast tumor initiating cells through activation of RAF1-β-catenin signaling.

Chang CJ, Yang JY, Xia W, Chen CT, Xie X, Chao CH, Woodward WA, Hsu JM, Hortobagyi GN, Hung MC.

Cancer Cell. 2011 Jan 18;19(1):86-100. doi: 10.1016/j.ccr.2010.10.035.


EZH2-mediated epigenetic repression of DNA repair in promoting breast tumor initiating cells.

Stefansson OA, Esteller M.

Breast Cancer Res. 2011 May 25;13(3):309. doi: 10.1186/bcr2871.


Polycomb group protein enhancer of zeste 2 is an oncogene that promotes the neoplastic transformation of a benign prostatic epithelial cell line.

Karanikolas BD, Figueiredo ML, Wu L.

Mol Cancer Res. 2009 Sep;7(9):1456-65. doi: 10.1158/1541-7786.MCR-09-0121.


Enhancer of zeste homolog 2 downregulates E-cadherin by mediating histone H3 methylation in gastric cancer cells.

Fujii S, Ochiai A.

Cancer Sci. 2008 Apr;99(4):738-46. doi: 10.1111/j.1349-7006.2008.00743.x.


EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells.

Kleer CG, Cao Q, Varambally S, Shen R, Ota I, Tomlins SA, Ghosh D, Sewalt RG, Otte AP, Hayes DF, Sabel MS, Livant D, Weiss SJ, Rubin MA, Chinnaiyan AM.

Proc Natl Acad Sci U S A. 2003 Sep 30;100(20):11606-11.


Interactions involving the Rad51 paralogs Rad51C and XRCC3 in human cells.

Wiese C, Collins DW, Albala JS, Thompson LH, Kronenberg A, Schild D.

Nucleic Acids Res. 2002 Feb 15;30(4):1001-8.


Integration of estrogen and Wnt signaling circuits by the polycomb group protein EZH2 in breast cancer cells.

Shi B, Liang J, Yang X, Wang Y, Zhao Y, Wu H, Sun L, Zhang Y, Chen Y, Li R, Zhang Y, Hong M, Shang Y.

Mol Cell Biol. 2007 Jul;27(14):5105-19.


Involvement of Rad51C in two distinct protein complexes of Rad51 paralogs in human cells.

Liu N, Schild D, Thelen MP, Thompson LH.

Nucleic Acids Res. 2002 Feb 15;30(4):1009-15.


Context-specific regulation of NF-κB target gene expression by EZH2 in breast cancers.

Lee ST, Li Z, Wu Z, Aau M, Guan P, Karuturi RK, Liou YC, Yu Q.

Mol Cell. 2011 Sep 2;43(5):798-810. doi: 10.1016/j.molcel.2011.08.011.


Complex formation by the human Rad51B and Rad51C DNA repair proteins and their activities in vitro.

Lio YC, Mazin AV, Kowalczykowski SC, Chen DJ.

J Biol Chem. 2003 Jan 24;278(4):2469-78.


Histone deacetylase inhibitors deplete enhancer of zeste 2 and associated polycomb repressive complex 2 proteins in human acute leukemia cells.

Fiskus W, Pranpat M, Balasis M, Herger B, Rao R, Chinnaiyan A, Atadja P, Bhalla K.

Mol Cancer Ther. 2006 Dec;5(12):3096-104.


The Arabidopsis RAD51 paralogs RAD51B, RAD51D and XRCC2 play partially redundant roles in somatic DNA repair and gene regulation.

Wang Y, Xiao R, Wang H, Cheng Z, Li W, Zhu G, Wang Y, Ma H.

New Phytol. 2014 Jan;201(1):292-304. doi: 10.1111/nph.12498.


Increased expression of the polycomb group gene, EZH2, in transitional cell carcinoma of the bladder.

Raman JD, Mongan NP, Tickoo SK, Boorjian SA, Scherr DS, Gudas LJ.

Clin Cancer Res. 2005 Dec 15;11(24 Pt 1):8570-6.


Xrcc3 is recruited to DNA double strand breaks early and independent of Rad51.

Forget AL, Bennett BT, Knight KL.

J Cell Biochem. 2004 Oct 15;93(3):429-36.


Expression changes in EZH2, but not in BMI-1, SIRT1, DNMT1 or DNMT3B are associated with DNA methylation changes in prostate cancer.

Hoffmann MJ, Engers R, Florl AR, Otte AP, Muller M, Schulz WA.

Cancer Biol Ther. 2007 Sep;6(9):1403-12.


Expression levels of the EZH2 polycomb transcriptional repressor correlate with aggressiveness and invasive potential of bladder carcinomas.

Weikert S, Christoph F, Köllermann J, Müller M, Schrader M, Miller K, Krause H.

Int J Mol Med. 2005 Aug;16(2):349-53.


A novel repressive E2F6 complex containing the polycomb group protein, EPC1, that interacts with EZH2 in a proliferation-specific manner.

Attwooll C, Oddi S, Cartwright P, Prosperini E, Agger K, Steensgaard P, Wagener C, Sardet C, Moroni MC, Helin K.

J Biol Chem. 2005 Jan 14;280(2):1199-208.


EZH2 regulates the transcription of estrogen-responsive genes through association with REA, an estrogen receptor corepressor.

Hwang C, Giri VN, Wilkinson JC, Wright CW, Wilkinson AS, Cooney KA, Duckett CS.

Breast Cancer Res Treat. 2008 Jan;107(2):235-42.


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