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Items: 1 to 20 of 114

1.

Regulation of muscle growth by multiple ligands signaling through activin type II receptors.

Lee SJ, Reed LA, Davies MV, Girgenrath S, Goad ME, Tomkinson KN, Wright JF, Barker C, Ehrmantraut G, Holmstrom J, Trowell B, Gertz B, Jiang MS, Sebald SM, Matzuk M, Li E, Liang LF, Quattlebaum E, Stotish RL, Wolfman NM.

Proc Natl Acad Sci U S A. 2005 Dec 13;102(50):18117-22. Epub 2005 Dec 5.

2.

Role of satellite cells versus myofibers in muscle hypertrophy induced by inhibition of the myostatin/activin signaling pathway.

Lee SJ, Huynh TV, Lee YS, Sebald SM, Wilcox-Adelman SA, Iwamori N, Lepper C, Matzuk MM, Fan CM.

Proc Natl Acad Sci U S A. 2012 Aug 28;109(35):E2353-60. doi: 10.1073/pnas.1206410109. Epub 2012 Aug 6.

3.

Blockade of activin type II receptors with a dual anti-ActRIIA/IIB antibody is critical to promote maximal skeletal muscle hypertrophy.

Morvan F, Rondeau JM, Zou C, Minetti G, Scheufler C, Scharenberg M, Jacobi C, Brebbia P, Ritter V, Toussaint G, Koelbing C, Leber X, Schilb A, Witte F, Lehmann S, Koch E, Geisse S, Glass DJ, Lach-Trifilieff E.

Proc Natl Acad Sci U S A. 2017 Nov 21;114(47):12448-12453. doi: 10.1073/pnas.1707925114. Epub 2017 Nov 6.

4.

Regulation of body mass growth through activin type IIB receptor in teleost fish.

Carpio Y, Acosta J, Morales R, Santisteban Y, Sanch├ęz A, Estrada MP.

Gen Comp Endocrinol. 2009 Jan 15;160(2):158-67. doi: 10.1016/j.ygcen.2008.11.009. Epub 2008 Nov 24.

PMID:
19056390
5.

Activin receptor type 2A (ACVR2A) functions directly in osteoblasts as a negative regulator of bone mass.

Goh BC, Singhal V, Herrera AJ, Tomlinson RE, Kim S, Faugere MC, Germain-Lee EL, Clemens TL, Lee SJ, DiGirolamo DJ.

J Biol Chem. 2017 Aug 18;292(33):13809-13822. doi: 10.1074/jbc.M117.782128. Epub 2017 Jun 28.

6.

A soluble activin receptor type IIB does not improve blood glucose in streptozotocin-treated mice.

Wang Q, Guo T, Portas J, McPherron AC.

Int J Biol Sci. 2015 Jan 5;11(2):199-208. doi: 10.7150/ijbs.10430. eCollection 2015.

7.

Myostatin, activin receptor IIb, and follistatin-like-3 gene expression are altered in adipose tissue and skeletal muscle of obese mice.

Allen DL, Cleary AS, Speaker KJ, Lindsay SF, Uyenishi J, Reed JM, Madden MC, Mehan RS.

Am J Physiol Endocrinol Metab. 2008 May;294(5):E918-27. doi: 10.1152/ajpendo.00798.2007. Epub 2008 Mar 11.

8.

Regulation of myostatin activity and muscle growth.

Lee SJ, McPherron AC.

Proc Natl Acad Sci U S A. 2001 Jul 31;98(16):9306-11. Epub 2001 Jul 17.

9.

Proteomic identification and functional validation of activins and bone morphogenetic protein 11 as candidate novel muscle mass regulators.

Souza TA, Chen X, Guo Y, Sava P, Zhang J, Hill JJ, Yaworsky PJ, Qiu Y.

Mol Endocrinol. 2008 Dec;22(12):2689-702. doi: 10.1210/me.2008-0290. Epub 2008 Oct 16.

10.

Gene expression profiling of skeletal muscles treated with a soluble activin type IIB receptor.

Rahimov F, King OD, Warsing LC, Powell RE, Emerson CP Jr, Kunkel LM, Wagner KR.

Physiol Genomics. 2011 Apr 27;43(8):398-407. doi: 10.1152/physiolgenomics.00223.2010. Epub 2011 Jan 25.

11.

An antibody blocking activin type II receptors induces strong skeletal muscle hypertrophy and protects from atrophy.

Lach-Trifilieff E, Minetti GC, Sheppard K, Ibebunjo C, Feige JN, Hartmann S, Brachat S, Rivet H, Koelbing C, Morvan F, Hatakeyama S, Glass DJ.

Mol Cell Biol. 2014 Feb;34(4):606-18. doi: 10.1128/MCB.01307-13. Epub 2013 Dec 2.

12.

Acute inhibition of myostatin-family proteins preserves skeletal muscle in mouse models of cancer cachexia.

Benny Klimek ME, Aydogdu T, Link MJ, Pons M, Koniaris LG, Zimmers TA.

Biochem Biophys Res Commun. 2010 Jan 15;391(3):1548-54. doi: 10.1016/j.bbrc.2009.12.123. Epub 2009 Dec 28.

PMID:
20036643
13.

Muscle growth in teleost fish is regulated by factors utilizing the activin II B receptor.

Phelps MP, Jaffe IM, Bradley TM.

J Exp Biol. 2013 Oct 1;216(Pt 19):3742-50. doi: 10.1242/jeb.086660. Epub 2013 Jun 20.

14.

An activin mutant with disrupted ALK4 binding blocks signaling via type II receptors.

Harrison CA, Gray PC, Fischer WH, Donaldson C, Choe S, Vale W.

J Biol Chem. 2004 Jul 2;279(27):28036-44. Epub 2004 Apr 27.

15.

Activin IIB receptor blockade attenuates dystrophic pathology in a mouse model of Duchenne muscular dystrophy.

Morine KJ, Bish LT, Selsby JT, Gazzara JA, Pendrak K, Sleeper MM, Barton ER, Lee SJ, Sweeney HL.

Muscle Nerve. 2010 Nov;42(5):722-30. doi: 10.1002/mus.21743.

16.

Exercise restores decreased physical activity levels and increases markers of autophagy and oxidative capacity in myostatin/activin-blocked mdx mice.

Hulmi JJ, Oliveira BM, Silvennoinen M, Hoogaars WM, Pasternack A, Kainulainen H, Ritvos O.

Am J Physiol Endocrinol Metab. 2013 Jul 15;305(2):E171-82. doi: 10.1152/ajpendo.00065.2013. Epub 2013 May 21.

17.

The effects of a soluble activin type IIB receptor on obesity and insulin sensitivity.

Akpan I, Goncalves MD, Dhir R, Yin X, Pistilli EE, Bogdanovich S, Khurana TS, Ucran J, Lachey J, Ahima RS.

Int J Obes (Lond). 2009 Nov;33(11):1265-73. doi: 10.1038/ijo.2009.162. Epub 2009 Aug 11.

18.

Structural and functional characterizations of activin type 2B receptor (acvr2b) ortholog from the marine fish, gilthead sea bream, Sparus aurata: evidence for gene duplication of acvr2b in fish.

Funkenstein B, Krol E, Esterin E, Kim YS.

J Mol Endocrinol. 2012 Oct 10;49(3):175-92. doi: 10.1530/JME-12-0075. Print 2012 Dec.

PMID:
22911153
19.

Regulation of myostatin signaling by c-Jun N-terminal kinase in C2C12 cells.

Huang Z, Chen D, Zhang K, Yu B, Chen X, Meng J.

Cell Signal. 2007 Nov;19(11):2286-95. Epub 2007 Aug 8.

PMID:
17689926
20.

Effects of heavy resistance training on myostatin mRNA and protein expression.

Willoughby DS.

Med Sci Sports Exerc. 2004 Apr;36(4):574-82.

PMID:
15064583

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