Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 181

1.

Orphan GPCRs and their ligands.

Civelli O, Saito Y, Wang Z, Nothacker HP, Reinscheid RK.

Pharmacol Ther. 2006 Jun;110(3):525-32. Epub 2005 Nov 9. Review.

PMID:
16289308
2.

Do orphan G-protein-coupled receptors have ligand-independent functions? New insights from receptor heterodimers.

Levoye A, Dam J, Ayoub MA, Guillaume JL, Jockers R.

EMBO Rep. 2006 Nov;7(11):1094-8. Review.

3.

Alternative drug discovery approaches for orphan GPCRs.

Levoye A, Jockers R.

Drug Discov Today. 2008 Jan;13(1-2):52-8. doi: 10.1016/j.drudis.2007.09.011. Epub 2007 Nov 19. Review.

PMID:
18190864
4.
5.

Orphan G protein-coupled receptors: targets for new therapeutic interventions.

Lin SH, Civelli O.

Ann Med. 2004;36(3):204-14. Review.

PMID:
15181976
6.

Functional assays for identifying ligands at orphan G protein-coupled receptors.

Szekeres PG.

Receptors Channels. 2002;8(5-6):297-308. Review.

PMID:
12690957
7.

Ligand screening system using fusion proteins of G protein-coupled receptors with G protein alpha subunits.

Suga H, Haga T.

Neurochem Int. 2007 Jul-Sep;51(2-4):140-64. Epub 2007 Jun 19. Review.

PMID:
17659814
8.

[The effects of anesthetics on G-protein-coupled receptors].

Minami K, Uezono Y.

Masui. 2005 Feb;54(2):118-25. Review. Japanese.

PMID:
15747504
9.

Gq protein-coupled receptors as targets for anesthetics.

Minami K, Uezono Y.

Curr Pharm Des. 2006;12(15):1931-7. Review.

PMID:
16724958
10.

Novel G-protein-coupled receptor genes expressed in the brain: continued discovery of important therapeutic targets.

Lee DK, George SR, O'Dowd BF.

Expert Opin Ther Targets. 2002 Apr;6(2):185-202. Review.

PMID:
12223080
11.

Constitutively activated G protein-coupled receptors: a novel approach to CNS drug discovery.

Menzaghi F, Behan DP, Chalmers DT.

Curr Drug Targets CNS Neurol Disord. 2002 Feb;1(1):105-21. Review.

PMID:
12769637
12.

Heterodimerization of g protein-coupled receptors: specificity and functional significance.

Prinster SC, Hague C, Hall RA.

Pharmacol Rev. 2005 Sep;57(3):289-98. Review.

13.

Orphan G protein-coupled receptors and obesity.

Xu YL, Jackson VR, Civelli O.

Eur J Pharmacol. 2004 Oct 1;500(1-3):243-53. Review.

PMID:
15464037
14.

[GPCRs heterodimerization: a new way towards the discovery of function for the orphan receptors?].

Levoye A, Jockers R.

Med Sci (Paris). 2007 Aug-Sep;23(8-9):746-50. Review. French.

15.

Using silico methods predicting ligands for orphan GPCRs.

Jiang Z, Zhou Y.

Curr Protein Pept Sci. 2006 Oct;7(5):459-64. Review.

PMID:
17073696
16.

Cellular and molecular biology of orphan G protein-coupled receptors.

Oh DY, Kim K, Kwon HB, Seong JY.

Int Rev Cytol. 2006;252:163-218. Review.

PMID:
16984818
17.

An ultra-HTS process for the identification of small molecule modulators of orphan G-protein-coupled receptors.

Cacace A, Banks M, Spicer T, Civoli F, Watson J.

Drug Discov Today. 2003 Sep 1;8(17):785-92. Review.

PMID:
12946641
18.

GPCR deorphanizations: the novel, the known and the unexpected transmitters.

Civelli O.

Trends Pharmacol Sci. 2005 Jan;26(1):15-9. Review.

PMID:
15629200
20.

The identification of ligands at orphan G-protein coupled receptors.

Wise A, Jupe SC, Rees S.

Annu Rev Pharmacol Toxicol. 2004;44:43-66. Review.

PMID:
14744238

Supplemental Content

Support Center