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Tbx1 expression in pharyngeal epithelia is necessary for pharyngeal arch artery development.

Zhang Z, Cerrato F, Xu H, Vitelli F, Morishima M, Vincentz J, Furuta Y, Ma L, Martin JF, Baldini A, Lindsay E.

Development. 2005 Dec;132(23):5307-15. Erratum in: Development. 2005;132(24):5614.


A genetic link between Tbx1 and fibroblast growth factor signaling.

Vitelli F, Taddei I, Morishima M, Meyers EN, Lindsay EA, Baldini A.

Development. 2002 Oct;129(19):4605-11.


Tbx1 haploinsufficieny in the DiGeorge syndrome region causes aortic arch defects in mice.

Lindsay EA, Vitelli F, Su H, Morishima M, Huynh T, Pramparo T, Jurecic V, Ogunrinu G, Sutherland HF, Scambler PJ, Bradley A, Baldini A.

Nature. 2001 Mar 1;410(6824):97-101.


Inactivation of Tbx1 in the pharyngeal endoderm results in 22q11DS malformations.

Arnold JS, Werling U, Braunstein EM, Liao J, Nowotschin S, Edelmann W, Hebert JM, Morrow BE.

Development. 2006 Mar;133(5):977-87. Epub 2006 Feb 1.


Tbx1 mutation causes multiple cardiovascular defects and disrupts neural crest and cranial nerve migratory pathways.

Vitelli F, Morishima M, Taddei I, Lindsay EA, Baldini A.

Hum Mol Genet. 2002 Apr 15;11(8):915-22.


Cre-mediated excision of Fgf8 in the Tbx1 expression domain reveals a critical role for Fgf8 in cardiovascular development in the mouse.

Brown CB, Wenning JM, Lu MM, Epstein DJ, Meyers EN, Epstein JA.

Dev Biol. 2004 Mar 1;267(1):190-202. Erratum in: Dev Biol. 2004 Jul 1;271(1):223.


The 22q11 deletion syndrome candidate gene Tbx1 determines thyroid size and positioning.

Fagman H, Liao J, Westerlund J, Andersson L, Morrow BE, Nilsson M.

Hum Mol Genet. 2007 Feb 1;16(3):276-85. Epub 2006 Dec 12.


Dissection of Tbx1 and Fgf interactions in mouse models of 22q11DS suggests functional redundancy.

Aggarwal VS, Liao J, Bondarev A, Schimmang T, Lewandoski M, Locker J, Shanske A, Campione M, Morrow BE.

Hum Mol Genet. 2006 Nov 1;15(21):3219-28. Epub 2006 Sep 25.


Ece1 and Tbx1 define distinct pathways to aortic arch morphogenesis.

Morishima M, Yanagisawa H, Yanagisawa M, Baldini A.

Dev Dyn. 2003 Sep;228(1):95-104.


Microarray analysis detects differentially expressed genes in the pharyngeal region of mice lacking Tbx1.

Ivins S, Lammerts van Beuren K, Roberts C, James C, Lindsay E, Baldini A, Ataliotis P, Scambler PJ.

Dev Biol. 2005 Sep 15;285(2):554-69.


The del22q11.2 candidate gene Tbx1 regulates branchiomeric myogenesis.

Kelly RG, Jerome-Majewska LA, Papaioannou VE.

Hum Mol Genet. 2004 Nov 15;13(22):2829-40. Epub 2004 Sep 22.


22q11 deletion syndrome: a role for TBX1 in pharyngeal and cardiovascular development.

Scambler PJ.

Pediatr Cardiol. 2010 Apr;31(3):378-90. doi: 10.1007/s00246-009-9613-0. Review.


Ripply3, a Tbx1 repressor, is required for development of the pharyngeal apparatus and its derivatives in mice.

Okubo T, Kawamura A, Takahashi J, Yagi H, Morishima M, Matsuoka R, Takada S.

Development. 2011 Jan;138(2):339-48. doi: 10.1242/dev.054056.


Tbx1 controls cardiac neural crest cell migration during arch artery development by regulating Gbx2 expression in the pharyngeal ectoderm.

Calmont A, Ivins S, Van Bueren KL, Papangeli I, Kyriakopoulou V, Andrews WD, Martin JF, Moon AM, Illingworth EA, Basson MA, Scambler PJ.

Development. 2009 Sep;136(18):3173-83. doi: 10.1242/dev.028902.


Tbx1 is regulated by tissue-specific forkhead proteins through a common Sonic hedgehog-responsive enhancer.

Yamagishi H, Maeda J, Hu T, McAnally J, Conway SJ, Kume T, Meyers EN, Yamagishi C, Srivastava D.

Genes Dev. 2003 Jan 15;17(2):269-81.


Inactivation of Bmp4 from the Tbx1 expression domain causes abnormal pharyngeal arch artery and cardiac outflow tract remodeling.

Nie X, Brown CB, Wang Q, Jiao K.

Cells Tissues Organs. 2011;193(6):393-403. doi: 10.1159/000321170. Epub 2010 Dec 1.


Tbx1 regulation of myogenic differentiation in the limb and cranial mesoderm.

Dastjerdi A, Robson L, Walker R, Hadley J, Zhang Z, Rodriguez-Niedenf├╝hr M, Ataliotis P, Baldini A, Scambler P, Francis-West P.

Dev Dyn. 2007 Feb;236(2):353-63.


Tbx1 regulates fibroblast growth factors in the anterior heart field through a reinforcing autoregulatory loop involving forkhead transcription factors.

Hu T, Yamagishi H, Maeda J, McAnally J, Yamagishi C, Srivastava D.

Development. 2004 Nov;131(21):5491-502. Epub 2004 Oct 6.


Fgf15 is required for proper morphogenesis of the mouse cardiac outflow tract.

Vincentz JW, McWhirter JR, Murre C, Baldini A, Furuta Y.

Genesis. 2005 Apr;41(4):192-201.


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