Similar articles for PMID: 16263722

Year	Number of Results
1995	1
1998	1
2000	5
2002	1
2003	5
2004	1
2005	10
2006	7
2007	6
2008	16
2009	16
2010	20
2011	30
2012	23
2013	21
2014	28
2015	12
2016	11
2017	5
2018	10
2019	9
2020	21
2021	19
2022	27
2023	9
2024	0

1

WNK1 regulates phosphorylation of cation-chloride-coupled cotransporters via the STE20-related kinases, SPAK and OSR1.

Moriguchi T, Urushiyama S, Hisamoto N, Iemura S, Uchida S, Natsume T, Matsumoto K, Shibuya H. Moriguchi T, et al. J Biol Chem. 2005 Dec 30;280(52):42685-93. doi: 10.1074/jbc.M510042200. Epub 2005 Oct 31. J Biol Chem. 2005. PMID: 16263722 Free article.

2

The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases.

Vitari AC, Deak M, Morrice NA, Alessi DR. Vitari AC, et al. Biochem J. 2005 Oct 1;391(Pt 1):17-24. doi: 10.1042/BJ20051180. Biochem J. 2005. PMID: 16083423 Free PMC article.

3

Functional interactions of the SPAK/OSR1 kinases with their upstream activator WNK1 and downstream substrate NKCC1.

Vitari AC, Thastrup J, Rafiqi FH, Deak M, Morrice NA, Karlsson HK, Alessi DR. Vitari AC, et al. Biochem J. 2006 Jul 1;397(1):223-31. doi: 10.1042/BJ20060220. Biochem J. 2006. PMID: 16669787 Free PMC article.

4

Activation of the thiazide-sensitive Na+-Cl- cotransporter by the WNK-regulated kinases SPAK and OSR1.

Richardson C, Rafiqi FH, Karlsson HK, Moleleki N, Vandewalle A, Campbell DG, Morrice NA, Alessi DR. Richardson C, et al. J Cell Sci. 2008 Mar 1;121(Pt 5):675-84. doi: 10.1242/jcs.025312. Epub 2008 Feb 12. J Cell Sci. 2008. PMID: 18270262

5

SPAK/OSR1 regulate NKCC1 and WNK activity: analysis of WNK isoform interactions and activation by T-loop trans-autophosphorylation.

Thastrup JO, Rafiqi FH, Vitari AC, Pozo-Guisado E, Deak M, Mehellou Y, Alessi DR. Thastrup JO, et al. Biochem J. 2012 Jan 1;441(1):325-37. doi: 10.1042/BJ20111879. Biochem J. 2012. PMID: 22032326 Free PMC article.

6

Interactions with WNK (with no lysine) family members regulate oxidative stress response 1 and ion co-transporter activity.

Sengupta S, Tu SW, Wedin K, Earnest S, Stippec S, Luby-Phelps K, Cobb MH. Sengupta S, et al. J Biol Chem. 2012 Nov 2;287(45):37868-79. doi: 10.1074/jbc.M112.398750. Epub 2012 Sep 18. J Biol Chem. 2012. PMID: 22989884 Free PMC article.

7

A novel Ste20-related proline/alanine-rich kinase (SPAK)-independent pathway involving calcium-binding protein 39 (Cab39) and serine threonine kinase with no lysine member 4 (WNK4) in the activation of Na-K-Cl cotransporters.

Ponce-Coria J, Markadieu N, Austin TM, Flammang L, Rios K, Welling PA, Delpire E. Ponce-Coria J, et al. J Biol Chem. 2014 Jun 20;289(25):17680-8. doi: 10.1074/jbc.M113.540518. Epub 2014 May 8. J Biol Chem. 2014. PMID: 24811174 Free PMC article.

8

WNK4 is indispensable for the pathogenesis of pseudohypoaldosteronism type II caused by mutant KLHL3.

Susa K, Sohara E, Takahashi D, Okado T, Rai T, Uchida S. Susa K, et al. Biochem Biophys Res Commun. 2017 Sep 23;491(3):727-732. doi: 10.1016/j.bbrc.2017.07.121. Epub 2017 Jul 22. Biochem Biophys Res Commun. 2017. PMID: 28743496

9

Effect of heterozygous deletion of WNK1 on the WNK-OSR1/ SPAK-NCC/NKCC1/NKCC2 signal cascade in the kidney and blood vessels.

Susa K, Kita S, Iwamoto T, Yang SS, Lin SH, Ohta A, Sohara E, Rai T, Sasaki S, Alessi DR, Uchida S. Susa K, et al. Clin Exp Nephrol. 2012 Aug;16(4):530-8. doi: 10.1007/s10157-012-0590-x. Clin Exp Nephrol. 2012. PMID: 22294159

10

Cation chloride cotransporters interact with the stress-related kinases Ste20-related proline-alanine-rich kinase (SPAK) and oxidative stress response 1 (OSR1).

Piechotta K, Lu J, Delpire E. Piechotta K, et al. J Biol Chem. 2002 Dec 27;277(52):50812-9. doi: 10.1074/jbc.M208108200. Epub 2002 Oct 16. J Biol Chem. 2002. PMID: 12386165 Free article.

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