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Items: 1 to 20 of 296

1.

The bacterial ribosome as a target for antibiotics.

Poehlsgaard J, Douthwaite S.

Nat Rev Microbiol. 2005 Nov;3(11):870-81. Review.

PMID:
16261170
2.

Macrolide antibiotic interaction and resistance on the bacterial ribosome.

Poehlsgaard J, Douthwaite S.

Curr Opin Investig Drugs. 2003 Feb;4(2):140-8. Review.

PMID:
12669373
3.

Macrolide antibiotics in the ribosome exit tunnel: species-specific binding and action.

Kannan K, Mankin AS.

Ann N Y Acad Sci. 2011 Dec;1241:33-47. doi: 10.1111/j.1749-6632.2011.06315.x. Review.

PMID:
22191525
4.

Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria.

Schlünzen F, Zarivach R, Harms J, Bashan A, Tocilj A, Albrecht R, Yonath A, Franceschi F.

Nature. 2001 Oct 25;413(6858):814-21.

PMID:
11677599
5.

The macrolide binding site on the bacterial ribosome.

Poehlsgaard J, Douthwaite S.

Curr Drug Targets Infect Disord. 2002 Mar;2(1):67-78. Review.

PMID:
12462154
6.

The bacterial ribosome, a promising focus for structure-based drug design.

Knowles DJ, Foloppe N, Matassova NB, Murchie AI.

Curr Opin Pharmacol. 2002 Oct;2(5):501-6. Review.

PMID:
12324250
7.
8.

Drugs targeting the ribosome.

Hermann T.

Curr Opin Struct Biol. 2005 Jun;15(3):355-66. Review.

PMID:
15919197
9.

Bacterial ribosomal subunit assembly is an antibiotic target.

Champney WS.

Curr Top Med Chem. 2003;3(9):929-47. Review.

PMID:
12678830
10.

Species-specific antibiotic-ribosome interactions: implications for drug development.

Wilson DN, Harms JM, Nierhaus KH, Schlünzen F, Fucini P.

Biol Chem. 2005 Dec;386(12):1239-52. Review.

PMID:
16336118
11.

Macrolide antibiotics: binding site, mechanism of action, resistance.

Gaynor M, Mankin AS.

Curr Top Med Chem. 2003;3(9):949-61. Review.

PMID:
12678831
12.
13.

Improving on nature: antibiotics that target the ribosome.

Sutcliffe JA.

Curr Opin Microbiol. 2005 Oct;8(5):534-42. Review.

PMID:
16111914
14.

Structural basis for aminoglycoside inhibition of bacterial ribosome recycling.

Borovinskaya MA, Pai RD, Zhang W, Schuwirth BS, Holton JM, Hirokawa G, Kaji H, Kaji A, Cate JH.

Nat Struct Mol Biol. 2007 Aug;14(8):727-32. Epub 2007 Jul 29.

PMID:
17660832
15.

Antibiotics targeting ribosomes: crystallographic studies.

Auerbach T, Bashan A, Harms J, Schluenzen F, Zarivach R, Bartels H, Agmon I, Kessler M, Pioletti M, Franceschi F, Yonath A.

Curr Drug Targets Infect Disord. 2002 Jun;2(2):169-86. Review. Erratum in: Curr Drug Targets Infect Disord. 2002 Dec;2(4):371, 373, and 375.

PMID:
12462147
16.

Binding and action of CEM-101, a new fluoroketolide antibiotic that inhibits protein synthesis.

Llano-Sotelo B, Dunkle J, Klepacki D, Zhang W, Fernandes P, Cate JH, Mankin AS.

Antimicrob Agents Chemother. 2010 Dec;54(12):4961-70. doi: 10.1128/AAC.00860-10. Epub 2010 Sep 20.

17.

The structural basis for the action of the antibiotics tetracycline, pactamycin, and hygromycin B on the 30S ribosomal subunit.

Brodersen DE, Clemons WM Jr, Carter AP, Morgan-Warren RJ, Wimberly BT, Ramakrishnan V.

Cell. 2000 Dec 22;103(7):1143-54.

18.

Molecular contacts between antibiotics and the 30S ribosomal particle.

Wirmer J, Westhof E.

Methods Enzymol. 2006;415:180-202.

PMID:
17116475
19.

Interplay between the ribosomal tunnel, nascent chain, and macrolides influences drug inhibition.

Starosta AL, Karpenko VV, Shishkina AV, Mikolajka A, Sumbatyan NV, Schluenzen F, Korshunova GA, Bogdanov AA, Wilson DN.

Chem Biol. 2010 May 28;17(5):504-14. doi: 10.1016/j.chembiol.2010.04.008.

20.

Components of the macrolide binding site on the ribosome.

Tejedor F, Ballesta JP.

J Antimicrob Chemother. 1985 Jul;16 Suppl A:53-62.

PMID:
4055551

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