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Items: 1 to 20 of 111

1.

Helicobacter pylori CagA induces a transition from polarized to invasive phenotypes in MDCK cells.

Bagnoli F, Buti L, Tompkins L, Covacci A, Amieva MR.

Proc Natl Acad Sci U S A. 2005 Nov 8;102(45):16339-44.

2.

Helicobacter pylori CagA protein induces factors involved in the epithelial to mesenchymal transition (EMT) in infected gastric epithelial cells in an EPIYA- phosphorylation-dependent manner.

Sougleri IS, Papadakos KS, Zadik MP, Mavri-Vavagianni M, Mentis AF, Sgouras DN.

FEBS J. 2016 Jan;283(2):206-20. doi: 10.1111/febs.13592.

PMID:
26907789
3.

EPIYA motif is a membrane-targeting signal of Helicobacter pylori virulence factor CagA in mammalian cells.

Higashi H, Yokoyama K, Fujii Y, Ren S, Yuasa H, Saadat I, Murata-Kamiya N, Azuma T, Hatakeyama M.

J Biol Chem. 2005 Jun 17;280(24):23130-7.

PMID:
15831497
4.
5.

[Oncogenic mechanism of Helicobacter pylori].

Hatakeyama M.

Nihon Rinsho Meneki Gakkai Kaishi. 2008 Jun;31(3):132-40. Japanese.

PMID:
18587223
6.

Helicobacter pylori CagA -- a bacterial intruder conspiring gastric carcinogenesis.

Hatakeyama M.

Int J Cancer. 2006 Sep 15;119(6):1217-23. Review.

7.

Natural variant of the Helicobacter pylori CagA oncoprotein that lost the ability to interact with PAR1.

Hashi K, Murata-Kamiya N, Varon C, Mégraud F, Dominguez-Bello MG, Hatakeyama M.

Cancer Sci. 2014 Mar;105(3):245-51. doi: 10.1111/cas.12342.

8.

c-Src and c-Abl kinases control hierarchic phosphorylation and function of the CagA effector protein in Western and East Asian Helicobacter pylori strains.

Mueller D, Tegtmeyer N, Brandt S, Yamaoka Y, De Poire E, Sgouras D, Wessler S, Torres J, Smolka A, Backert S.

J Clin Invest. 2012 Apr;122(4):1553-66. doi: 10.1172/JCI61143.

9.

Interaction of CagA with Crk plays an important role in Helicobacter pylori-induced loss of gastric epithelial cell adhesion.

Suzuki M, Mimuro H, Suzuki T, Park M, Yamamoto T, Sasakawa C.

J Exp Med. 2005 Nov 7;202(9):1235-47.

10.

Structural basis and functional consequence of Helicobacter pylori CagA multimerization in cells.

Ren S, Higashi H, Lu H, Azuma T, Hatakeyama M.

J Biol Chem. 2006 Oct 27;281(43):32344-52.

PMID:
16954210
11.

Helicobacter pylori and gastric carcinogenesis.

Hatakeyama M.

J Gastroenterol. 2009;44(4):239-48. doi: 10.1007/s00535-009-0014-1. Review.

PMID:
19271114
12.

Presence of terminal EPIYA phosphorylation motifs in Helicobacter pylori CagA contributes to IL-8 secretion, irrespective of the number of repeats.

Papadakos KS, Sougleri IS, Mentis AF, Hatziloukas E, Sgouras DN.

PLoS One. 2013;8(2):e56291. doi: 10.1371/journal.pone.0056291.

13.

Helicobacter pylori CagA induces Ras-independent morphogenetic response through SHP-2 recruitment and activation.

Higashi H, Nakaya A, Tsutsumi R, Yokoyama K, Fujii Y, Ishikawa S, Higuchi M, Takahashi A, Kurashima Y, Teishikata Y, Tanaka S, Azuma T, Hatakeyama M.

J Biol Chem. 2004 Apr 23;279(17):17205-16.

PMID:
14963045
14.

Differential oncogenic potential of geographically distinct Helicobacter pylori CagA isoforms in mice.

Miura M, Ohnishi N, Tanaka S, Yanagiya K, Hatakeyama M.

Int J Cancer. 2009 Dec 1;125(11):2497-504. doi: 10.1002/ijc.24740.

15.

A specific A/T polymorphism in Western tyrosine phosphorylation B-motifs regulates Helicobacter pylori CagA epithelial cell interactions.

Zhang XS, Tegtmeyer N, Traube L, Jindal S, Perez-Perez G, Sticht H, Backert S, Blaser MJ.

PLoS Pathog. 2015 Feb 3;11(2):e1004621. doi: 10.1371/journal.ppat.1004621.

16.

A novel inhibitory domain of Helicobacter pylori protein CagA reduces CagA effects on host cell biology.

Pelz C, Steininger S, Weiss C, Coscia F, Vogelmann R.

J Biol Chem. 2011 Mar 18;286(11):8999-9008. doi: 10.1074/jbc.M110.166504.

17.

Helicobacter pylori generates cells with cancer stem cell properties via epithelial-mesenchymal transition-like changes.

Bessède E, Staedel C, Acuña Amador LA, Nguyen PH, Chambonnier L, Hatakeyama M, Belleannée G, Mégraud F, Varon C.

Oncogene. 2014 Aug 7;33(32):4123-31. doi: 10.1038/onc.2013.380.

PMID:
24096479
18.

Linking epithelial polarity and carcinogenesis by multitasking Helicobacter pylori virulence factor CagA.

Hatakeyama M.

Oncogene. 2008 Nov 24;27(55):7047-54. doi: 10.1038/onc.2008.353. Review.

PMID:
19029944
19.

[ Helicobacter pylori oncoprotein CagA and bacterial EPIYA effector family].

Hatakeyama M.

Seikagaku. 2014 Dec;86(6):744-54. Review. Japanese. No abstract available.

PMID:
25675812
20.

Helicobacter pylori CagA targets PAR1/MARK kinase to disrupt epithelial cell polarity.

Saadat I, Higashi H, Obuse C, Umeda M, Murata-Kamiya N, Saito Y, Lu H, Ohnishi N, Azuma T, Suzuki A, Ohno S, Hatakeyama M.

Nature. 2007 May 17;447(7142):330-3.

PMID:
17507984
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