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Items: 1 to 20 of 102

1.

Partially adenosine deaminase-deficient mice develop pulmonary fibrosis in association with adenosine elevations.

Chunn JL, Mohsenin A, Young HW, Lee CG, Elias JA, Kellems RE, Blackburn MR.

Am J Physiol Lung Cell Mol Physiol. 2006 Mar;290(3):L579-87. Epub 2005 Oct 28.

2.

Adenosine-dependent pulmonary fibrosis in adenosine deaminase-deficient mice.

Chunn JL, Molina JG, Mi T, Xia Y, Kellems RE, Blackburn MR.

J Immunol. 2005 Aug 1;175(3):1937-46.

3.

Adenosine-dependent airway inflammation and hyperresponsiveness in partially adenosine deaminase-deficient mice.

Chunn JL, Young HW, Banerjee SK, Colasurdo GN, Blackburn MR.

J Immunol. 2001 Oct 15;167(8):4676-85.

4.

Adenosine metabolism and murine strain-specific IL-4-induced inflammation, emphysema, and fibrosis.

Ma B, Blackburn MR, Lee CG, Homer RJ, Liu W, Flavell RA, Boyden L, Lifton RP, Sun CX, Young HW, Elias JA.

J Clin Invest. 2006 May;116(5):1274-83.

5.

Genetic removal of the A2A adenosine receptor enhances pulmonary inflammation, mucin production, and angiogenesis in adenosine deaminase-deficient mice.

Mohsenin A, Mi T, Xia Y, Kellems RE, Chen JF, Blackburn MR.

Am J Physiol Lung Cell Mol Physiol. 2007 Sep;293(3):L753-61. Epub 2007 Jun 29.

6.

Smad3 null mice develop airspace enlargement and are resistant to TGF-beta-mediated pulmonary fibrosis.

Bonniaud P, Kolb M, Galt T, Robertson J, Robbins C, Stampfli M, Lavery C, Margetts PJ, Roberts AB, Gauldie J.

J Immunol. 2004 Aug 1;173(3):2099-108.

7.

Role of A2B adenosine receptor signaling in adenosine-dependent pulmonary inflammation and injury.

Sun CX, Zhong H, Mohsenin A, Morschl E, Chunn JL, Molina JG, Belardinelli L, Zeng D, Blackburn MR.

J Clin Invest. 2006 Aug;116(8):2173-2182.

8.

A3 adenosine receptor signaling contributes to airway inflammation and mucus production in adenosine deaminase-deficient mice.

Young HW, Molina JG, Dimina D, Zhong H, Jacobson M, Chan LN, Chan TS, Lee JJ, Blackburn MR.

J Immunol. 2004 Jul 15;173(2):1380-9.

9.

IL-11 receptor alpha in the pathogenesis of IL-13-induced inflammation and remodeling.

Chen Q, Rabach L, Noble P, Zheng T, Lee CG, Homer RJ, Elias JA.

J Immunol. 2005 Feb 15;174(4):2305-13.

10.

Adenosine-mediated mast cell degranulation in adenosine deaminase-deficient mice.

Zhong H, Chunn JL, Volmer JB, Fozard JR, Blackburn MR.

J Pharmacol Exp Ther. 2001 Aug;298(2):433-40.

11.

Corticosteroids prevent myofibroblast accumulation and airway remodeling in mice.

Miller M, Cho JY, McElwain K, McElwain S, Shim JY, Manni M, Baek JS, Broide DH.

Am J Physiol Lung Cell Mol Physiol. 2006 Jan;290(1):L162-9.

12.

Enhanced CXCL1 production and angiogenesis in adenosine-mediated lung disease.

Mohsenin A, Burdick MD, Molina JG, Keane MP, Blackburn MR.

FASEB J. 2007 Apr;21(4):1026-36. Epub 2007 Jan 16.

PMID:
17227950
13.

Metabolic consequences of adenosine deaminase deficiency in mice are associated with defects in alveogenesis, pulmonary inflammation, and airway obstruction.

Blackburn MR, Volmer JB, Thrasher JL, Zhong H, Crosby JR, Lee JJ, Kellems RE.

J Exp Med. 2000 Jul 17;192(2):159-70.

14.

Transforming growth factor-beta receptor type 1 (TGFbetaRI) kinase activity but not p38 activation is required for TGFbetaRI-induced myofibroblast differentiation and profibrotic gene expression.

Kapoun AM, Gaspar NJ, Wang Y, Damm D, Liu YW, O'young G, Quon D, Lam A, Munson K, Tran TT, Ma JY, Murphy A, Dugar S, Chakravarty S, Protter AA, Wen FQ, Liu X, Rennard SI, Higgins LS.

Mol Pharmacol. 2006 Aug;70(2):518-31. Epub 2006 May 17.

15.
16.

Adenosine deaminase deficiency: metabolic basis of immune deficiency and pulmonary inflammation.

Blackburn MR, Kellems RE.

Adv Immunol. 2005;86:1-41. Review.

PMID:
15705418
17.

Mice lacking cystathionine beta synthase have lung fibrosis and air space enlargement.

Hamelet J, Maurin N, Fulchiron R, Delabar JM, Janel N.

Exp Mol Pathol. 2007 Oct;83(2):249-53. Epub 2007 May 6.

PMID:
17543941
18.

Interleukin-6 contributes to inflammation and remodeling in a model of adenosine mediated lung injury.

Pedroza M, Schneider DJ, Karmouty-Quintana H, Coote J, Shaw S, Corrigan R, Molina JG, Alcorn JL, Galas D, Gelinas R, Blackburn MR.

PLoS One. 2011;6(7):e22667. doi: 10.1371/journal.pone.0022667. Epub 2011 Jul 25.

19.

Inhibition of allergen-induced airway remodeling in Smad 3-deficient mice.

Le AV, Cho JY, Miller M, McElwain S, Golgotiu K, Broide DH.

J Immunol. 2007 Jun 1;178(11):7310-6.

20.

The latent form of TGFbeta(1) is induced by TNFalpha through an ERK specific pathway and is activated by asbestos-derived reactive oxygen species in vitro and in vivo.

Sullivan DE, Ferris M, Pociask D, Brody AR.

J Immunotoxicol. 2008 Apr;5(2):145-9. doi: 10.1080/15476910802085822.

PMID:
18569384

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