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Items: 1 to 20 of 130

1.

Both early and delayed treatment with melanocortin 4 receptor-stimulating melanocortins produces neuroprotection in cerebral ischemia.

Giuliani D, Mioni C, Altavilla D, Leone S, Bazzani C, Minutoli L, Bitto A, Cainazzo MM, Marini H, Zaffe D, Botticelli AR, Pizzala R, Savio M, Necchi D, Schiöth HB, Bertolini A, Squadrito F, Guarini S.

Endocrinology. 2006 Mar;147(3):1126-35. Epub 2005 Oct 27.

PMID:
16254026
2.

Broad therapeutic treatment window of [Nle(4), D-Phe(7)]alpha-melanocyte-stimulating hormone for long-lasting protection against ischemic stroke, in Mongolian gerbils.

Giuliani D, Leone S, Mioni C, Bazzani C, Zaffe D, Botticelli AR, Altavilla D, Galantucci M, Minutoli L, Bitto A, Squadrito F, Guarini S.

Eur J Pharmacol. 2006 May 24;538(1-3):48-56. Epub 2006 Mar 24.

PMID:
16647700
3.

Melanocortin MC₄ receptor agonists counteract late inflammatory and apoptotic responses and improve neuronal functionality after cerebral ischemia.

Spaccapelo L, Bitto A, Galantucci M, Ottani A, Irrera N, Minutoli L, Altavilla D, Novellino E, Grieco P, Zaffe D, Squadrito F, Giuliani D, Guarini S.

Eur J Pharmacol. 2011 Nov 30;670(2-3):479-86. doi: 10.1016/j.ejphar.2011.09.015. Epub 2011 Sep 21.

PMID:
21946115
4.

Treatment of cerebral ischemia with melanocortins acting at MC4 receptors induces marked neurogenesis and long-lasting functional recovery.

Giuliani D, Zaffe D, Ottani A, Spaccapelo L, Galantucci M, Minutoli L, Bitto A, Irrera N, Contri M, Altavilla D, Botticelli AR, Squadrito F, Guarini S.

Acta Neuropathol. 2011 Oct;122(4):443-53. doi: 10.1007/s00401-011-0873-4. Epub 2011 Sep 17.

PMID:
21927944
5.

Functional recovery after delayed treatment of ischemic stroke with melanocortins is associated with overexpression of the activity-dependent gene Zif268.

Giuliani D, Ottani A, Minutoli L, Stefano VD, Galantucci M, Bitto A, Zaffe D, Altavilla D, Botticelli AR, Squadrito F, Guarini S.

Brain Behav Immun. 2009 Aug;23(6):844-50. doi: 10.1016/j.bbi.2009.03.009. Epub 2009 Apr 5.

PMID:
19345727
6.

Neuroprotection in focal cerebral ischemia owing to delayed treatment with melanocortins.

Giuliani D, Ottani A, Mioni C, Bazzani C, Galantucci M, Minutoli L, Bitto A, Zaffe D, Botticelli AR, Squadrito F, Guarini S.

Eur J Pharmacol. 2007 Sep 10;570(1-3):57-65. Epub 2007 Jun 5.

PMID:
17588564
7.

Melanocortins protect against brain damage and counteract cognitive decline in a transgenic mouse model of moderate Alzheimer׳s disease.

Giuliani D, Galantucci M, Neri L, Canalini F, Calevro A, Bitto A, Ottani A, Vandini E, Sena P, Sandrini M, Squadrito F, Zaffe D, Guarini S.

Eur J Pharmacol. 2014 Oct 5;740:144-50. doi: 10.1016/j.ejphar.2014.06.063. Epub 2014 Jul 15.

PMID:
25034807
8.

Up-regulation of the canonical Wnt-3A and Sonic hedgehog signaling underlies melanocortin-induced neurogenesis after cerebral ischemia.

Spaccapelo L, Galantucci M, Neri L, Contri M, Pizzala R, D'Amico R, Ottani A, Sandrini M, Zaffe D, Giuliani D, Guarini S.

Eur J Pharmacol. 2013 May 5;707(1-3):78-86. doi: 10.1016/j.ejphar.2013.03.030. Epub 2013 Mar 25.

PMID:
23535605
9.

Melanocortins defend their territory: multifaceted neuroprotection in cerebral ischemia.

Tatro JB.

Endocrinology. 2006 Mar;147(3):1122-5. No abstract available.

PMID:
16481482
11.

NDP-α-MSH induces intense neurogenesis and cognitive recovery in Alzheimer transgenic mice through activation of melanocortin MC4 receptors.

Giuliani D, Neri L, Canalini F, Calevro A, Ottani A, Vandini E, Sena P, Zaffe D, Guarini S.

Mol Cell Neurosci. 2015 Jul;67:13-21. doi: 10.1016/j.mcn.2015.05.004. Epub 2015 May 21.

PMID:
26003413
12.

Asp10 in Lys-gamma2-MSH determines selective activation of the melanocortin MC3 receptor.

Oosterom J, Burbach JP, Gispen WH, Adan RA.

Eur J Pharmacol. 1998 Jul 31;354(1):R9-11.

PMID:
9726642
13.

Melanocortins and cardiovascular regulation.

Versteeg DH, Van Bergen P, Adan RA, De Wildt DJ.

Eur J Pharmacol. 1998 Oct 30;360(1):1-14. Review.

PMID:
9845266
14.

Melanocortins protect against progression of Alzheimer's disease in triple-transgenic mice by targeting multiple pathophysiological pathways.

Giuliani D, Bitto A, Galantucci M, Zaffe D, Ottani A, Irrera N, Neri L, Cavallini GM, Altavilla D, Botticelli AR, Squadrito F, Guarini S.

Neurobiol Aging. 2014 Mar;35(3):537-47. doi: 10.1016/j.neurobiolaging.2013.08.030. Epub 2013 Oct 1.

PMID:
24094579
15.

Anxiety-like behavior induced by IL-1beta is modulated by alpha-MSH through central melanocortin-4 receptors.

Cragnolini AB, Schiöth HB, Scimonelli TN.

Peptides. 2006 Jun;27(6):1451-6. Epub 2005 Dec 1.

PMID:
16325304
16.

Selective melanocortin MC4 receptor agonists reverse haemorrhagic shock and prevent multiple organ damage.

Giuliani D, Mioni C, Bazzani C, Zaffe D, Botticelli AR, Capolongo S, Sabba A, Galantucci M, Iannone A, Grieco P, Novellino E, Colombo G, Tomasi A, Catania A, Guarini S.

Br J Pharmacol. 2007 Mar;150(5):595-603. Epub 2007 Jan 22.

17.

Characterization of melanocortin receptor ligands on cloned brain melanocortin receptors and on grooming behavior in the rat.

Adan RA, Szklarczyk AW, Oosterom J, Brakkee JH, Nijenhuis WA, Schaaper WM, Meloen RH, Gispen WH.

Eur J Pharmacol. 1999 Aug 13;378(3):249-58.

PMID:
10493100
18.

Further evidence that melanocortins prevent myocardial reperfusion injury by activating melanocortin MC3 receptors.

Mioni C, Giuliani D, Cainazzo MM, Leone S, Bazzani C, Grieco P, Novellino E, Tomasi A, Bertolini A, Guarini S.

Eur J Pharmacol. 2003 Sep 23;477(3):227-34. Erratum in: Eur J Pharmacol. 2004 Feb 20;486(2):237. Iannone C [corrected to Iannone A].

PMID:
14522361
19.

Vagus nerve mediates the protective effects of melanocortins against cerebral and systemic damage after ischemic stroke.

Ottani A, Giuliani D, Mioni C, Galantucci M, Minutoli L, Bitto A, Altavilla D, Zaffe D, Botticelli AR, Squadrito F, Guarini S.

J Cereb Blood Flow Metab. 2009 Mar;29(3):512-23. doi: 10.1038/jcbfm.2008.140. Epub 2008 Nov 19.

PMID:
19018269
20.

Multiple beneficial effects of melanocortin MC4 receptor agonists in experimental neurodegenerative disorders: Therapeutic perspectives.

Giuliani D, Ottani A, Neri L, Zaffe D, Grieco P, Jochem J, Cavallini GM, Catania A, Guarini S.

Prog Neurobiol. 2017 Jan;148:40-56. doi: 10.1016/j.pneurobio.2016.11.004. Epub 2016 Dec 1. Review.

PMID:
27916623

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