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Items: 1 to 20 of 93

1.

Inhibition of phosphatidylinositol-3-kinase causes increased sensitivity to radiation through a PKB-dependent mechanism.

Gottschalk AR, Doan A, Nakamura JL, Stokoe D, Haas-Kogan DA.

Int J Radiat Oncol Biol Phys. 2005 Nov 15;63(4):1221-7.

PMID:
16253776
2.

Inhibition of phosphatidylinositol-3-kinase causes cell death through a protein kinase B (PKB)-dependent mechanism and growth arrest through a PKB-independent mechanism.

Gottschalk AR, Doan A, Nakamura JL, Haas-Kogan DA, Stokoe D.

Int J Radiat Oncol Biol Phys. 2005 Mar 15;61(4):1183-8.

PMID:
15752900
3.

Long-term androgen-ablation causes increased resistance to PI3K/Akt pathway inhibition in prostate cancer cells.

Pfeil K, Eder IE, Putz T, Ramoner R, Culig Z, Ueberall F, Bartsch G, Klocker H.

Prostate. 2004 Feb 15;58(3):259-68.

PMID:
14743465
5.

Phosphatidylinositol 3-kinase inhibition by LY294002 radiosensitizes human cervical cancer cell lines.

Lee CM, Fuhrman CB, Planelles V, Peltier MR, Gaffney DK, Soisson AP, Dodson MK, Tolley HD, Green CL, Zempolich KA.

Clin Cancer Res. 2006 Jan 1;12(1):250-6.

6.

PKB/Akt mediates radiosensitization by the signaling inhibitor LY294002 in human malignant gliomas.

Nakamura JL, Karlsson A, Arvold ND, Gottschalk AR, Pieper RO, Stokoe D, Haas-Kogan DA.

J Neurooncol. 2005 Feb;71(3):215-22.

PMID:
15735908
8.

Phosphoinositide-3-kinase inhibition enhances radiosensitization of cervical cancer in vivo.

Liu Y, Cui B, Qiao Y, Zhang Y, Tian Y, Jiang J, Ma D, Kong B.

Int J Gynecol Cancer. 2011 Jan;21(1):100-5. doi: 10.1097/IGC.0b013e3182021bfd.

PMID:
21330835
9.

Regulation of protein kinase B activity by PTEN and SHIP2 in human prostate-derived cell lines.

Sharrard RM, Maitland NJ.

Cell Signal. 2007 Jan;19(1):129-38.

PMID:
16842970
10.

Inhibition of the phosphatidylinositol 3'-kinase pathway promotes autocrine Fas-induced death of phosphatase and tensin homologue-deficient prostate cancer cells.

Bertram J, Peacock JW, Tan C, Mui AL, Chung SW, Gleave ME, Dedhar S, Cox ME, Ong CJ.

Cancer Res. 2006 May 1;66(9):4781-8.

11.

The Akt-inhibitor Erufosine induces apoptotic cell death in prostate cancer cells and increases the short term effects of ionizing radiation.

Rudner J, Ruiner CE, Handrick R, Eibl HJ, Belka C, Jendrossek V.

Radiat Oncol. 2010 Nov 16;5:108. doi: 10.1186/1748-717X-5-108.

12.

Pro-survival function of Akt/protein kinase B in prostate cancer cells. Relationship with TRAIL resistance.

Thakkar H, Chen X, Tyan F, Gim S, Robinson H, Lee C, Pandey SK, Nwokorie C, Onwudiwe N, Srivastava RK.

J Biol Chem. 2001 Oct 19;276(42):38361-9. Retraction in: J Biol Chem. 2002 Aug 16;277(33):30408.

PMID:
11461904
13.

[Activation of phosphatidylinositol 3-kinase-protein kinase B (PI3K-PKB) induced by 17beta-estradiol in endometrial carcinoma cell (Ishikawa)].

Guo RX, Wei LH, Wang JL, Sun PM, Sun XL.

Zhonghua Fu Chan Ke Za Zhi. 2004 Jul;39(7):469-73. Chinese.

PMID:
15347471
14.

Selective inhibition of survival signal transduction pathways enhanced radiosensitivity in human esophageal cancer cell lines in vitro.

Akimoto T, Nonaka T, Harashima K, Ishikawa H, Sakurai H, Mitsuhashi N.

Anticancer Res. 2004 Mar-Apr;24(2B):811-9.

17.

Bcl-xL mediates a survival mechanism independent of the phosphoinositide 3-kinase/Akt pathway in prostate cancer cells.

Yang CC, Lin HP, Chen CS, Yang YT, Tseng PH, Rangnekar VM, Chen CS.

J Biol Chem. 2003 Jul 11;278(28):25872-8.

PMID:
12738789
18.
19.

Constitutively active Akt is an important regulator of TRAIL sensitivity in prostate cancer.

Chen X, Thakkar H, Tyan F, Gim S, Robinson H, Lee C, Pandey SK, Nwokorie C, Onwudiwe N, Srivastava RK.

Oncogene. 2001 Sep 20;20(42):6073-83.

20.

Role of the phosphatidylinositol 3'-kinase/PTEN/Akt kinase pathway in the overexpression of fatty acid synthase in LNCaP prostate cancer cells.

Van de Sande T, De Schrijver E, Heyns W, Verhoeven G, Swinnen JV.

Cancer Res. 2002 Feb 1;62(3):642-6.

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