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Items: 1 to 20 of 461

1.

The AID antibody diversification enzyme is regulated by protein kinase A phosphorylation.

Basu U, Chaudhuri J, Alpert C, Dutt S, Ranganath S, Li G, Schrum JP, Manis JP, Alt FW.

Nature. 2005 Nov 24;438(7067):508-11. Epub 2005 Oct 26.

PMID:
16251902
2.

Role of activation-induced deaminase protein kinase A phosphorylation sites in Ig gene conversion and somatic hypermutation.

Chatterji M, Unniraman S, McBride KM, Schatz DG.

J Immunol. 2007 Oct 15;179(8):5274-80.

3.

PKA-mediated phosphorylation regulates the function of activation-induced deaminase (AID) in B cells.

Pasqualucci L, Kitaura Y, Gu H, Dalla-Favera R.

Proc Natl Acad Sci U S A. 2006 Jan 10;103(2):395-400. Epub 2005 Dec 30.

4.

Replication protein A interacts with AID to promote deamination of somatic hypermutation targets.

Chaudhuri J, Khuong C, Alt FW.

Nature. 2004 Aug 26;430(7003):992-8. Epub 2004 Jul 25.

5.

Transcription-targeted DNA deamination by the AID antibody diversification enzyme.

Chaudhuri J, Tian M, Khuong C, Chua K, Pinaud E, Alt FW.

Nature. 2003 Apr 17;422(6933):726-30. Epub 2003 Apr 9.

PMID:
12692563
6.

Regulation of hypermutation by activation-induced cytidine deaminase phosphorylation.

McBride KM, Gazumyan A, Woo EM, Barreto VM, Robbiani DF, Chait BT, Nussenzweig MC.

Proc Natl Acad Sci U S A. 2006 Jun 6;103(23):8798-803. Epub 2006 May 24.

7.
8.

Separate domains of AID are required for somatic hypermutation and class-switch recombination.

Shinkura R, Ito S, Begum NA, Nagaoka H, Muramatsu M, Kinoshita K, Sakakibara Y, Hijikata H, Honjo T.

Nat Immunol. 2004 Jul;5(7):707-12. Epub 2004 Jun 13.

PMID:
15195091
9.

Integrity of the AID serine-38 phosphorylation site is critical for class switch recombination and somatic hypermutation in mice.

Cheng HL, Vuong BQ, Basu U, Franklin A, Schwer B, Astarita J, Phan RT, Datta A, Manis J, Alt FW, Chaudhuri J.

Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2717-22. doi: 10.1073/pnas.0812304106. Epub 2009 Feb 5. Erratum in: Proc Natl Acad Sci U S A. 2013 Apr 2;110(14):5731.

11.

Processive AID-catalysed cytosine deamination on single-stranded DNA simulates somatic hypermutation.

Pham P, Bransteitter R, Petruska J, Goodman MF.

Nature. 2003 Jul 3;424(6944):103-7. Epub 2003 Jun 18.

PMID:
12819663
12.

Evolution of class switch recombination function in fish activation-induced cytidine deaminase, AID.

Wakae K, Magor BG, Saunders H, Nagaoka H, Kawamura A, Kinoshita K, Honjo T, Muramatsu M.

Int Immunol. 2006 Jan;18(1):41-7. Epub 2005 Nov 15.

PMID:
16291656
13.

Evolution of phosphorylation-dependent regulation of activation-induced cytidine deaminase.

Basu U, Wang Y, Alt FW.

Mol Cell. 2008 Oct 24;32(2):285-91. doi: 10.1016/j.molcel.2008.08.019.

14.

Negative regulation of activation-induced cytidine deaminase in B cells.

Muto T, Okazaki IM, Yamada S, Tanaka Y, Kinoshita K, Muramatsu M, Nagaoka H, Honjo T.

Proc Natl Acad Sci U S A. 2006 Feb 21;103(8):2752-7. Epub 2006 Feb 13.

15.

Regulation of activation induced deaminase via phosphorylation.

Basu U, Chaudhuri J, Phan RT, Datta A, Alt FW.

Adv Exp Med Biol. 2007;596:129-37. Review.

PMID:
17338181
16.
17.

Activation-induced deaminase: light and dark sides.

de Yébenes VG, Ramiro AR.

Trends Mol Med. 2006 Sep;12(9):432-9. Epub 2006 Jul 24. Review.

PMID:
16861038
18.

The AID enzyme induces class switch recombination in fibroblasts.

Okazaki IM, Kinoshita K, Muramatsu M, Yoshikawa K, Honjo T.

Nature. 2002 Mar 21;416(6878):340-5. Epub 2002 Mar 3.

PMID:
11875397
19.

Target sequence accessibility limits activation-induced cytidine deaminase activity in primary mediastinal B-cell lymphoma.

Popov SW, Moldenhauer G, Wotschke B, Brüderlein S, Barth TF, Dorsch K, Ritz O, Möller P, Leithäuser F.

Cancer Res. 2007 Jul 15;67(14):6555-64.

20.

The C-terminal region of activation-induced cytidine deaminase is responsible for a recombination function other than DNA cleavage in class switch recombination.

Doi T, Kato L, Ito S, Shinkura R, Wei M, Nagaoka H, Wang J, Honjo T.

Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2758-63. doi: 10.1073/pnas.0813253106. Epub 2009 Feb 6.

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