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Zinc finger nucleases: custom-designed molecular scissors for genome engineering of plant and mammalian cells.

Durai S, Mani M, Kandavelou K, Wu J, Porteus MH, Chandrasegaran S.

Nucleic Acids Res. 2005 Oct 26;33(18):5978-90. Print 2005. Review.


Custom-designed zinc finger nucleases: what is next?

Wu J, Kandavelou K, Chandrasegaran S.

Cell Mol Life Sci. 2007 Nov;64(22):2933-44. Review.


Custom-designed molecular scissors for site-specific manipulation of the plant and mammalian genomes.

Kandavelou K, Chandrasegaran S.

Methods Mol Biol. 2009;544:617-36. doi: 10.1007/978-1-59745-483-4_40.


Creating designed zinc-finger nucleases with minimal cytotoxicity.

Ramalingam S, Kandavelou K, Rajenderan R, Chandrasegaran S.

J Mol Biol. 2011 Jan 21;405(3):630-41. doi: 10.1016/j.jmb.2010.10.043. Epub 2010 Nov 19.


A toolbox and procedural notes for characterizing novel zinc finger nucleases for genome editing in plant cells.

Tovkach A, Zeevi V, Tzfira T.

Plant J. 2009 Feb;57(4):747-57. doi: 10.1111/j.1365-313X.2008.03718.x. Epub 2008 Nov 24.


Genome editing with CompoZr custom zinc finger nucleases (ZFNs).

Hansen K, Coussens MJ, Sago J, Subramanian S, Gjoka M, Briner D.

J Vis Exp. 2012 Jun 14;(64):e3304. doi: 10.3791/3304.


Design, engineering, and characterization of zinc finger nucleases.

Mani M, Kandavelou K, Dy FJ, Durai S, Chandrasegaran S.

Biochem Biophys Res Commun. 2005 Sep 23;335(2):447-57.


Targeted gene addition to a predetermined site in the human genome using a ZFN-based nicking enzyme.

Wang J, Friedman G, Doyon Y, Wang NS, Li CJ, Miller JC, Hua KL, Yan JJ, Babiarz JE, Gregory PD, Holmes MC.

Genome Res. 2012 Jul;22(7):1316-26. doi: 10.1101/gr.122879.111. Epub 2012 Mar 20.


Autonomous zinc-finger nuclease pairs for targeted chromosomal deletion.

Söllü C, Pars K, Cornu TI, Thibodeau-Beganny S, Maeder ML, Joung JK, Heilbronn R, Cathomen T.

Nucleic Acids Res. 2010 Dec;38(22):8269-76. doi: 10.1093/nar/gkq720. Epub 2010 Aug 16.


Origins of Programmable Nucleases for Genome Engineering.

Chandrasegaran S, Carroll D.

J Mol Biol. 2016 Feb 27;428(5 Pt B):963-89. doi: 10.1016/j.jmb.2015.10.014. Epub 2015 Oct 23. Review.


Zinc Finger Nucleases: A new era for transgenic animals.

Swarthout JT, Raisinghani M, Cui X.

Ann Neurosci. 2011 Jan;18(1):25-8. doi: 10.5214/ans.0972.7531.1118109. Review.


An improved zinc-finger nuclease architecture for highly specific genome editing.

Miller JC, Holmes MC, Wang J, Guschin DY, Lee YL, Rupniewski I, Beausejour CM, Waite AJ, Wang NS, Kim KA, Gregory PD, Pabo CO, Rebar EJ.

Nat Biotechnol. 2007 Jul;25(7):778-85. Epub 2007 Jul 1.


Directed evolution of an enhanced and highly efficient FokI cleavage domain for zinc finger nucleases.

Guo J, Gaj T, Barbas CF 3rd.

J Mol Biol. 2010 Jul 2;400(1):96-107. doi: 10.1016/j.jmb.2010.04.060. Epub 2010 May 4.


Targeted genome editing in pluripotent stem cells using zinc-finger nucleases.

Bobis-Wozowicz S, Osiak A, Rahman SH, Cathomen T.

Methods. 2011 Apr;53(4):339-46. doi: 10.1016/j.ymeth.2010.12.019. Epub 2010 Dec 23.


Creating zinc finger nucleases to manipulate the genome in a site-specific manner using a modular-assembly approach.

Porteus M.

Cold Spring Harb Protoc. 2010 Dec 1;2010(12):pdb.top93. doi: 10.1101/pdb.top93.


Increasing frequencies of site-specific mutagenesis and gene targeting in Arabidopsis by manipulating DNA repair pathways.

Qi Y, Zhang Y, Zhang F, Baller JA, Cleland SC, Ryu Y, Starker CG, Voytas DF.

Genome Res. 2013 Mar;23(3):547-54. doi: 10.1101/gr.145557.112. Epub 2013 Jan 2.


Genome engineering with zinc-finger nucleases.

Carroll D.

Genetics. 2011 Aug;188(4):773-82. doi: 10.1534/genetics.111.131433. Review.


Targeting DNA double-strand breaks with TAL effector nucleases.

Christian M, Cermak T, Doyle EL, Schmidt C, Zhang F, Hummel A, Bogdanove AJ, Voytas DF.

Genetics. 2010 Oct;186(2):757-61. doi: 10.1534/genetics.110.120717. Epub 2010 Jul 26.


Targeted gene addition into a specified location in the human genome using designed zinc finger nucleases.

Moehle EA, Rock JM, Lee YL, Jouvenot Y, DeKelver RC, Gregory PD, Urnov FD, Holmes MC.

Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3055-60. Epub 2007 Feb 20. Erratum in: Proc Natl Acad Sci U S A. 2007 Apr 3;104(14):6090. Moehle, E A [corrected to Moehle, Erica A]; Rock, J M [corrected to Rock, Jeremy M]; Lee, Y L [corrected to Lee, Ya-Li]; Jouvenot, Y [corrected to Jouvenot, Yann]; Dekelver, R C [corrected to DeKelver, Russell C]; Gregory, P D [corrected to Gregory, Philip D]; Urnov, F D [corrected to Urnov, Fyodor D]; Holmes, M C [corrected to Holmes, Michael C].


ZFN-induced mutagenesis and gene-targeting in Arabidopsis through Agrobacterium-mediated floral dip transformation.

de Pater S, Neuteboom LW, Pinas JE, Hooykaas PJ, van der Zaal BJ.

Plant Biotechnol J. 2009 Oct;7(8):821-35. doi: 10.1111/j.1467-7652.2009.00446.x.

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