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A posttranscriptional role for the yeast Paf1-RNA polymerase II complex is revealed by identification of primary targets.

Penheiter KL, Washburn TM, Porter SE, Hoffman MG, Jaehning JA.

Mol Cell. 2005 Oct 28;20(2):213-23.


From transcription to mRNA: PAF provides a new path.

Rosonina E, Manley JL.

Mol Cell. 2005 Oct 28;20(2):167-8. Review.


The Paf1 complex has functions independent of actively transcribing RNA polymerase II.

Mueller CL, Porter SE, Hoffman MG, Jaehning JA.

Mol Cell. 2004 May 21;14(4):447-56.


Direct interactions between the Paf1 complex and a cleavage and polyadenylation factor are revealed by dissociation of Paf1 from RNA polymerase II.

Nordick K, Hoffman MG, Betz JL, Jaehning JA.

Eukaryot Cell. 2008 Jul;7(7):1158-67. doi: 10.1128/EC.00434-07. Epub 2008 May 9.


Phenotypic analysis of Paf1/RNA polymerase II complex mutations reveals connections to cell cycle regulation, protein synthesis, and lipid and nucleic acid metabolism.

Betz JL, Chang M, Washburn TM, Porter SE, Mueller CL, Jaehning JA.

Mol Genet Genomics. 2002 Oct;268(2):272-85. Epub 2002 Sep 12.


The parafibromin tumor suppressor protein is part of a human Paf1 complex.

Rozenblatt-Rosen O, Hughes CM, Nannepaga SJ, Shanmugam KS, Copeland TD, Guszczynski T, Resau JH, Meyerson M.

Mol Cell Biol. 2005 Jan;25(2):612-20.


Ctr9, Rtf1, and Leo1 are components of the Paf1/RNA polymerase II complex.

Mueller CL, Jaehning JA.

Mol Cell Biol. 2002 Apr;22(7):1971-80.


Molecular evidence indicating that the yeast PAF complex is required for transcription elongation.

Rondón AG, Gallardo M, García-Rubio M, Aguilera A.

EMBO Rep. 2004 Jan;5(1):47-53.


The Paf1 complex: platform or player in RNA polymerase II transcription?

Jaehning JA.

Biochim Biophys Acta. 2010 May-Jun;1799(5-6):379-88. doi: 10.1016/j.bbagrm.2010.01.001. Epub 2010 Jan 12. Review.


The Paf1 complex promotes displacement of histones upon rapid induction of transcription by RNA polymerase II.

Marton HA, Desiderio S.

BMC Mol Biol. 2008 Jan 14;9:4. doi: 10.1186/1471-2199-9-4.


A Requirement for the Saccharomyces cerevisiae Paf1 complex in snoRNA 3' end formation.

Sheldon KE, Mauger DM, Arndt KM.

Mol Cell. 2005 Oct 28;20(2):225-36.


Depletion of trypanosome CTR9 leads to gene expression defects.

Ouna BA, Nyambega B, Manful T, Helbig C, Males M, Fadda A, Clayton C.

PLoS One. 2012;7(4):e34256. doi: 10.1371/journal.pone.0034256. Epub 2012 Apr 20.


Mutants of the Paf1 complex alter phenotypic expression of the yeast prion [PSI+].

Strawn LA, Lin CA, Tank EM, Osman MM, Simpson SA, True HL.

Mol Biol Cell. 2009 Apr;20(8):2229-41. doi: 10.1091/mbc.E08-08-0813. Epub 2009 Feb 18.


hCTR9, a component of Paf1 complex, participates in the transcription of interleukin 6-responsive genes through regulation of STAT3-DNA interactions.

Youn MY, Yoo HS, Kim MJ, Hwang SY, Choi Y, Desiderio SV, Yoo JY.

J Biol Chem. 2007 Nov 30;282(48):34727-34. Epub 2007 Oct 1.


The yeast Rat1 exonuclease promotes transcription termination by RNA polymerase II.

Kim M, Krogan NJ, Vasiljeva L, Rando OJ, Nedea E, Greenblatt JF, Buratowski S.

Nature. 2004 Nov 25;432(7016):517-22. Erratum in: Nature. 2005 Feb 10;433(7026):661.


The Paf1 complex physically and functionally associates with transcription elongation factors in vivo.

Squazzo SL, Costa PJ, Lindstrom DL, Kumer KE, Simic R, Jennings JL, Link AJ, Arndt KM, Hartzog GA.

EMBO J. 2002 Apr 2;21(7):1764-74.


A yeast heterogeneous nuclear ribonucleoprotein complex associated with RNA polymerase II.

Conrad NK, Wilson SM, Steinmetz EJ, Patturajan M, Brow DA, Swanson MS, Corden JL.

Genetics. 2000 Feb;154(2):557-71.


The Paf1 complex represses SER3 transcription in Saccharomyces cerevisiae by facilitating intergenic transcription-dependent nucleosome occupancy of the SER3 promoter.

Pruneski JA, Hainer SJ, Petrov KO, Martens JA.

Eukaryot Cell. 2011 Oct;10(10):1283-94. doi: 10.1128/EC.05141-11. Epub 2011 Aug 26.


Proteome analysis of a CTR9 deficient yeast strain suggests that Ctr9 has function(s) independent of the Paf1 complex.

Massoni-Laporte A, Perrot M, Ponger L, Boucherie H, Guieysse-Peugeot AL.

Biochim Biophys Acta. 2012 May;1824(5):759-68. doi: 10.1016/j.bbapap.2012.02.010. Epub 2012 Mar 8.


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