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Items: 1 to 20 of 181

1.

Modeling T cell antigen discrimination based on feedback control of digital ERK responses.

Altan-Bonnet G, Germain RN.

PLoS Biol. 2005 Nov;3(11):e356. Epub 2005 Oct 25.

2.

The dynamics of T cell receptor signaling: complex orchestration and the key roles of tempo and cooperation.

Germain RN, Stefanová I.

Annu Rev Immunol. 1999;17:467-522. Review.

PMID:
10358766
3.

TCR ligand discrimination is enforced by competing ERK positive and SHP-1 negative feedback pathways.

Stefanová I, Hemmer B, Vergelli M, Martin R, Biddison WE, Germain RN.

Nat Immunol. 2003 Mar;4(3):248-54. Epub 2003 Feb 10.

PMID:
12577055
4.

Involvement of the SHP-1 tyrosine phosphatase in regulation of T cell selection.

Zhang J, Somani AK, Yuen D, Yang Y, Love PE, Siminovitch KA.

J Immunol. 1999 Sep 15;163(6):3012-21.

5.

CD5 negatively regulates the T-cell antigen receptor signal transduction pathway: involvement of SH2-containing phosphotyrosine phosphatase SHP-1.

Perez-Villar JJ, Whitney GS, Bowen MA, Hewgill DH, Aruffo AA, Kanner SB.

Mol Cell Biol. 1999 Apr;19(4):2903-12.

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7.

CD22 is a functional ligand for SH2 domain-containing protein-tyrosine phosphatase-1 in primary T cells.

Sathish JG, Walters J, Luo JC, Johnson KG, Leroy FG, Brennan P, Kim KP, Gygi SP, Neel BG, Matthews RJ.

J Biol Chem. 2004 Nov 12;279(46):47783-91. Epub 2004 Sep 10.

8.

Docking protein Gab2 is phosphorylated by ZAP-70 and negatively regulates T cell receptor signaling by recruitment of inhibitory molecules.

Yamasaki S, Nishida K, Hibi M, Sakuma M, Shiina R, Takeuchi A, Ohnishi H, Hirano T, Saito T.

J Biol Chem. 2001 Nov 30;276(48):45175-83. Epub 2001 Sep 25.

11.

Active Ca2+/calmodulin-dependent protein kinase II gamma B impairs positive selection of T cells by modulating TCR signaling.

McGargill MA, Sharp LL, Bui JD, Hedrick SM, Calbo S.

J Immunol. 2005 Jul 15;175(2):656-64.

12.

TCR-dependent cell response is modulated by the timing of CD43 engagement.

Fierro NA, Pedraza-Alva G, Rosenstein Y.

J Immunol. 2006 Jun 15;176(12):7346-53.

13.

A THEMIS:SHP1 complex promotes T-cell survival.

Paster W, Bruger AM, Katsch K, Grégoire C, Roncagalli R, Fu G, Gascoigne NR, Nika K, Cohnen A, Feller SM, Simister PC, Molder KC, Cordoba SP, Dushek O, Malissen B, Acuto O.

EMBO J. 2015 Feb 3;34(3):393-409. doi: 10.15252/embj.201387725. Epub 2014 Dec 22.

14.

Contributions of the T cell receptor-associated CD3gamma-ITAM to thymocyte selection.

Haks MC, Pépin E, van den Brakel JH, Smeele SA, Belkowski SM, Kessels HW, Krimpenfort P, Kruisbeek AM.

J Exp Med. 2002 Jul 1;196(1):1-13.

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17.

Themis sets the signal threshold for positive and negative selection in T-cell development.

Fu G, Casas J, Rigaud S, Rybakin V, Lambolez F, Brzostek J, Hoerter JA, Paster W, Acuto O, Cheroutre H, Sauer K, Gascoigne NR.

Nature. 2013 Dec 19;504(7480):441-5. doi: 10.1038/nature12718. Epub 2013 Nov 13.

18.

Ectopic B-Raf expression enhances extracellular signal-regulated kinase (ERK) signaling in T cells and prevents antigen-presenting cell-induced anergy.

Dillon TJ, Karpitski V, Wetzel SA, Parker DC, Shaw AS, Stork PJ.

J Biol Chem. 2003 Sep 19;278(38):35940-9. Epub 2003 Jul 10.

19.

T cell receptor binding kinetics required for T cell activation depend on the density of cognate ligand on the antigen-presenting cell.

González PA, Carreño LJ, Coombs D, Mora JE, Palmieri E, Goldstein B, Nathenson SG, Kalergis AM.

Proc Natl Acad Sci U S A. 2005 Mar 29;102(13):4824-9. Epub 2005 Mar 16.

20.

T-cell receptor triggering is critically dependent on the dimensions of its peptide-MHC ligand.

Choudhuri K, Wiseman D, Brown MH, Gould K, van der Merwe PA.

Nature. 2005 Jul 28;436(7050):578-82.

PMID:
16049493

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