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Items: 1 to 20 of 110


Function of the MAPK scaffold protein, Ste5, requires a cryptic PH domain.

Garrenton LS, Young SL, Thorner J.

Genes Dev. 2006 Jul 15;20(14):1946-58.


Nucleus-specific and cell cycle-regulated degradation of mitogen-activated protein kinase scaffold protein Ste5 contributes to the control of signaling competence.

Garrenton LS, Braunwarth A, Irniger S, Hurt E, K├╝nzler M, Thorner J.

Mol Cell Biol. 2009 Jan;29(2):582-601. doi: 10.1128/MCB.01019-08. Epub 2008 Nov 10.


Dual role for membrane localization in yeast MAP kinase cascade activation and its contribution to signaling fidelity.

Lamson RE, Takahashi S, Winters MJ, Pryciak PM.

Curr Biol. 2006 Mar 21;16(6):618-23.


Structural determinants of the specificity of a membrane binding domain of the scaffold protein Ste5 of budding yeast: implications in signaling by the scaffold protein in MAPK pathway.

Bhunia A, Mohanram H, Bhattacharjya S.

Biochim Biophys Acta. 2012 May;1818(5):1250-60. doi: 10.1016/j.bbamem.2012.01.008. Epub 2012 Jan 20.


Cdc24 regulates nuclear shuttling and recruitment of the Ste5 scaffold to a heterotrimeric G protein in Saccharomyces cerevisiae.

Wang Y, Chen W, Simpson DM, Elion EA.

J Biol Chem. 2005 Apr 1;280(13):13084-96. Epub 2005 Jan 18.


The shuttling scaffold model for prevention of yeast pheromone pathway misactivation.

Singh AP, Andries E, Edwards JS, Steinberg S.

Bull Math Biol. 2012 Dec;74(12):2861-74. doi: 10.1007/s11538-012-9785-2. Epub 2012 Oct 27.


Ste5 RING-H2 domain: role in Ste4-promoted oligomerization for yeast pheromone signaling.

Inouye C, Dhillon N, Thorner J.

Science. 1997 Oct 3;278(5335):103-6.


A mechanism for cell-cycle regulation of MAP kinase signaling in a yeast differentiation pathway.

Strickfaden SC, Winters MJ, Ben-Ari G, Lamson RE, Tyers M, Pryciak PM.

Cell. 2007 Feb 9;128(3):519-31.


Counteractive control of polarized morphogenesis during mating by mitogen-activated protein kinase Fus3 and G1 cyclin-dependent kinase.

Yu L, Qi M, Sheff MA, Elion EA.

Mol Biol Cell. 2008 Apr;19(4):1739-52. doi: 10.1091/mbc.E07-08-0757. Epub 2008 Feb 6.


Persistent activation by constitutive Ste7 promotes Kss1-mediated invasive growth but fails to support Fus3-dependent mating in yeast.

Maleri S, Ge Q, Hackett EA, Wang Y, Dohlman HG, Errede B.

Mol Cell Biol. 2004 Oct;24(20):9221-38.


Formin-induced actin cables are required for polarized recruitment of the Ste5 scaffold and high level activation of MAPK Fus3.

Qi M, Elion EA.

J Cell Sci. 2005 Jul 1;118(Pt 13):2837-48. Epub 2005 Jun 16. Erratum in: J Cell Sci. 2007 Feb 15;120(Pt 4):712.


Pheromone-induced anisotropy in yeast plasma membrane phosphatidylinositol-4,5-bisphosphate distribution is required for MAPK signaling.

Garrenton LS, Stefan CJ, McMurray MA, Emr SD, Thorner J.

Proc Natl Acad Sci U S A. 2010 Jun 29;107(26):11805-10. doi: 10.1073/pnas.1005817107. Epub 2010 Jun 14.


The Ste5p scaffold.

Elion EA.

J Cell Sci. 2001 Nov;114(Pt 22):3967-78. Review.

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